Israeli drone strikes hit Kamal Adwan Hospital on Tuesday, wounding three medical staff at one of the few hospitals still partially operating in the northernmost part of Gaza , the facility’s director said. Dr. Hossam Abu Safiya said the drones were dropping bombs, spraying shrapnel at the hospital. There was no immediate comment from the Israeli military. In Lebanon, a tenuous ceasefire between Israel and Hezbollah has held despite Israeli forces carrying out several new drone and artillery strikes on Tuesday, killing a shepherd in the country's south. Israeli Prime Minister Benjamin Netanyahu vowed keep striking “with an iron fist” against perceived Hezbollah violations of the ceasefire. Hezbollah began launching rockets, drones and missiles into Israel last year in solidarity with Hamas militants who are fighting in the Gaza Strip. The war in Gaza began when Hamas-led militants stormed into southern Israel on Oct. 7, 2023, killing some 1,200 people, mostly civilians, and taking around 250 people hostage . Israel’s blistering retaliatory offensive has killed at least 44,500 Palestinians , more than half of them women and children, according to Gaza’s Health Ministry, which does not say how many of the dead were combatants. Israel says it has killed over 17,000 militants, without providing evidence. The war in Gaza has destroyed vast areas of the coastal enclave and displaced 90% of the population of 2.3 million, often multiple times . Here's the Latest: WASHINGTON — U.S. forces conducted a self-defense strike Tuesday in the vicinity of Mission Support Site Euphrates, a U.S. base in eastern Syria, against three truck-mounted multiple rocket launchers, a T-64 tank and mortars that Pentagon press secretary Maj. Gen. Pat Ryder said presented “a clear and imminent threat” to U.S. troops. The self-defense strike occurred after rockets and mortars were fired that landed in the vicinity of the base, Ryder said. The Pentagon is still assessing who was responsible for the attacks — that there are both Iranian-backed militias and Syrian military forces that operate in the area. Ryder said the attack was not connected to the offensive that is ongoing in Aleppo, where Syrian jihadi-led rebels have advanced and taken over the country’s capital city. The U.S. has about 900 troops in Syria to conduct missions to counter the Islamic Stage group. CAIRO — Israeli drone strikes hit the Kamal Adwan Hospital in northern Gaza on Tuesday, wounding three medical personnel, the facility’s director said. Dr. Hossam Abu Safiya said the drones were dropping bombs, spraying shrapnel at the hospital, located in the town of Beit Lahiya. There was no immediate comment from the Israeli military. In comments released by Gaza’s Health Ministry, Abu Safiya said one of the injured was in critical condition and was undergoing a complex surgery. “The situation has become extremely dangerous,” he said. “We are exhausted by the ongoing violence and atrocities.” Kamal Adwan Hospital has been struck multiple times over the past two months as Israeli forces have waged a fierce offensive in the area, saying they are rooting out Hamas militants who regrouped there. In October, Israeli forces raided the hospital, saying that militants were sheltering inside and arrested a number of people, including some staff. Hospital officials denied the claim. Abu Safiya was wounded in his thigh and back by an Israeli drone strike on the hospital last month. TEL AVIV, Israel — An Israeli court has ordered Prime Minister Benjamin Netanyahu to take the stand next week in his long-running corruption trial, ending a long series of delays. Netanyahu’s lawyers had filed multiple requests to put off the testimony, arguing first that the war in Gaza prevented him from properly preparing for his testimony, and later that his security could not be guaranteed in the court chamber. In Tuesday’s decision, judges in the Jerusalem district court said that following a security assessment, his testimony will be moved to the Tel Aviv district court. Israeli media said the session would take place in an underground chamber. His testimony in the trial, which began in 2020, is expected to begin on Dec. 10 and to last at least several weeks. Netanyahu is charged with fraud, breach of trust and accepting bribes in three separate scandals involving powerful media moguls and wealthy associates. He denies wrongdoing. NABATIYEH, Lebanon — In destroyed areas of southern Lebanon, residents clearing away rubble on Tuesday said they didn’t trust Israel to abide by the week-old ceasefire with Hezbollah. “The Israelis are breaching the ceasefire whenever they can because they are not committed,” said Hussein Badreddin, a vegetable seller in the southern city of Nabatiyeh, which was pummeled by Israeli airstrikes over several weeks. “This means that they (can) breach any resolution at any time.” Since it began last Wednesday, the U.S.- and French-brokered 60-day ceasefire has been rattled by near daily Israeli strikes, although Israel has been vague about the purported Hezbollah violations that prompted them. Imad Yassin, a trader who owns a clothing shop in Nabatiyeh, said Israel was constantly breaching the ceasefire because Israeli Prime Minister Benjamin Netanyahu wants to continue the displacement of residents of southern Lebanon. “The Israeli enemy was defeated and the truth is that he is trying to get revenge. Netanyahu is trying to displace us as citizens of southern Lebanon,” Yassin said. They spoke as bulldozers cleared streets strewn with rubble and debris from destroyed buildings. Electricians worked to fix power lines in an effort to restore electricity to the city. Both men were displaced by the war and returned to Nabatiyeh on Wednesday, the day the ceasefire went into effect. Yassin found his clothing shop had been destroyed. He said he would wait to see if the state will dispense compensation funds so that he can repair and reopen his business. GAZA CITY, Gaza Strip — Two separate Israeli airstrikes killed at least nine people in Gaza City on Tuesday, Palestinian medical authorities said. Six people, including two children, who were killed when an Israeli strike hit a school sheltering displaced people Tuesday afternoon in the Zaytoun neighborhood, according to the Health Ministry’s emergency services. A second strike hit a residential building in the Sabra neighborhood, killing at least three people, the services said. Israeli forces have almost completely isolated northernmost Gaza since early October, saying they’re fighting regrouped Hamas militants there. That has pushed some families south to Gaza City, while hundreds of thousands more live in the territory's center and south in squalid tent camps, where they rely on international aid. JERUSALEM — Israel's military confirmed it killed a senior member of Hezbollah responsible for coordinating with Syria's army on rearming and resupplying the Lebanese militant group. Syrian state media said a drone strike on Tuesday hit a car in a suburb of the capital Damascus, killing one person, without saying who was killed. Israel's military said he was Salman Nemer Jomaa, describing him as “Hezbollah’s representative to the Syrian military,” and that killing him “degrades both Hezbollah’s presence in Syria and Hezbollah’s ongoing force-building efforts.” Israel has carried out hundreds of strikes on targets inside government-controlled parts of war-torn Syria in recent years. Israel rarely acknowledges its actions in Syria, but it has said that it targets bases of Iran-allied militant groups. Iran supports both Hezbollah and the Syrian government of President Bashar Assad, which is currently fighting to push back jihadi-led insurgents who seized the country’s largest city of Aleppo . TUBAS, West Bank — Israeli soldiers opened fire inside a hospital in the occupied West Bank on Tuesday during a raid to seize the bodies of alleged militants targeted in earlier airstrikes, a Palestinian doctor working at the hospital told The Associated Press. Soldiers entered the Turkish Hospital complex in Tubas after the bodies of two Palestinians killed and one wounded in airstrikes in the northern West Bank on Tuesday were brought there, said Dr. Mahmoud Ghanam, who works in the hospital’s emergency department. The troops briefly handcuffed and arrested Ghanam and another doctor. “The army entered in a brutal way, and they were shooting inside the emergency department,” said Ghanam. “They handcuffed us and took me and my colleague.” The military confirmed that its troops were operating around the hospital searching for those targeted in the airstrikes, which they said had hit a militant cell near the Palestinian town of Al-Aqaba in the Jordan Valley. It denied that troops had entered the hospital building or fired gunshots inside. The soldiers left after learning that the wounded man had been transferred to another hospital, Ghanam said. The soldiers wanted to take the bodies of the two men killed in the strike, but the hospital’s manager refused to hand over the bodies, Ghanam said. Israeli raids on hospitals in the West Bank are rare but have grown more common since the start of the Israel-Hamas war. In Gaza, Israeli troops have systematically besieged, raided and damaged many hospitals. About 800 Palestinians have been killed by Israeli fire in the West Bank since Hamas’ Oct. 7, 2023 attack out of Gaza ignited the war there. Israel has carried out near-daily military raids in the West Bank that it says are aimed at preventing attacks on Israelis — attacks which have also been on the rise. Israel captured the West Bank, the Gaza Strip and east Jerusalem in the 1967 Mideast war. The Palestinians seek all three territories for an independent state. CAIRO — Palestinian officials say Fatah and Hamas are closing in on an agreement to appoint a committee of politically independent technocrats to administer the Gaza Strip after the war . It would effectively end Hamas’ rule and could help advance ceasefire talks with Israel. The rival factions have made several failed attempts to reconcile since Hamas seized power in Gaza in 2007. Israel has meanwhile ruled out any postwar role in Gaza for either Hamas or Fatah, which dominates the Western-backed Palestinian Authority . A Palestinian Authority official on Tuesday confirmed that a preliminary agreement had been reached following weeks of negotiations in Cairo. The official said the committee would have 12-15 members, most of them from Gaza. It would report to the Palestinian Authority, which is headquartered in the Israeli-occupied West Bank, and work with local and international parties to facilitate humanitarian assistance and reconstruction. A Hamas official said that Hamas and Fatah had agreed on the general terms but were still negotiating over some details and the individuals who would serve on the committee. The official said an agreement would be announced after a meeting of all Palestinian factions in Cairo, without providing a timeline. Both officials spoke on condition of anonymity because they were not authorized to brief media on the talks. There was no immediate comment from Israel. Israeli Prime Minister Benjamin Netanyahu has vowed to continue the war until Hamas is dismantled and scores of hostages are returned. He says Israel will maintain open-ended security control over Gaza , with civilian affairs administered by local Palestinians unaffiliated with the Palestinian Authority or Hamas. No Palestinians have publicly volunteered for such a role, and Hamas has threatened anyone who cooperates with the Israeli military. The United States has called for a revitalized Palestinian Authority to govern both the West Bank and Gaza ahead of eventual statehood. The Israeli government is opposed to Palestinian statehood. Associated Press writers Samy Magdy in Cairo and Josef Federman in Jerusalem contributed. NUSEIRAT REFUGEE CAMP, Gaza Strip — Palestinians lined up for bags of flour distributed by the U.N. in central Gaza on Tuesday morning, some of them for the first time in months amid a drop in food aid entering the territory. The U.N. agency for Palestinian refugees, known as UNRWA, gave out one 25-kilogram flour bag (55 pounds) to each family of 10 at a warehouse in the Nuseirat refugee camp, as well as further south in the city of Khan Younis. Jalal al-Shaer, among the dozens receiving flour at the Nuseirat warehouse, said the bag would last his family of 12 for only two or three days. “The situation for us is very difficult,” said another man in line, Hammad Moawad. “There is no flour, there is no food, prices are high ... We eat bread crumbs.” He said his family hadn’t received a flour allotment in five or six months. COGAT, the Israeli army body in charge of humanitarian affairs, said it facilitated entry of a shipment of 600 tons of flour on Sunday for the World Food Program. Still, the amount of aid Israel has allowed into Gaza since the beginning of October has been at nearly the lowest levels of the 15-month-old war. UNRWA’s senior emergency officer Louise Wateridge told The Associated Press that the flour bags being distributed Tuesday were not enough. “People are getting one bag of flour between an entire family and there is no certainty when they’ll receive the next food,” she said. Wateridge added that UNRWA has been struggling like other humanitarian agencies to provide much needed supplies across the Gaza Strip. The agency this week announced it was stopping delivering aid entering through the main crossing from Israel, Kerem Shalom, because its convoys were being robbed by gangs. UNRWA has blamed Israel in large part for the spread of lawlessness in Gaza. The International Criminal Court is seeking to arrest Israeli Prime Minister Benjamin Netanyahu and his former defense minister over accusations of using “starvation as a method of warfare” by restricting humanitarian aid into Gaza. Israel rejects the allegations and says it has been working hard to improve entry of aid. JERUSALEM — Israeli Prime Minister Benjamin Netanyahu says the war isn't over against Hezbollah and vowed to use "an iron fist" against the Lebanese militant group for any perceived violations of a week-old ceasefire. “At the moment we are in a ceasefire, I note — a ceasefire, not the end of the war," Netanyahu said at the start of the government meeting Tuesday. He said the military would retaliate for “any violation — minor or major.” Netanyahu also thanked U.S. President-elect Donald Trump for his recent demands for Hamas to release the remaining Israeli hostages in Gaza. Trump posted on social media Monday that if the hostages are not freed before he takes office in January there would be “HELL TO PAY.” Netanyahu convened Tuesday's meeting in northern Israel, where around 45,000 Israelis had been displaced by the war as of last week, according to the prime minister’s office. Netanyahu said the government was focused on getting them back in their homes and rehabilitating the area. BERLIN — German authorities have arrested a Lebanese man accused of being a member of Hezbollah and working for groups controlled by the militant organization in Germany. Federal prosecutors said the suspect, identified only as Fadel R. in line with German privacy rules, was arrested in the Hannover region on Tuesday. The man is suspected of membership in a foreign terrorist organization and is not accused of direct involvement in any violence. Prosecutors said he joined Hezbollah in the summer of 2008 or earlier and took part in leadership training courses in Lebanon. From 2009, he allegedly had leadership duties in two groups controlled by Hezbollah in the Hannover area, organizing appearances by preachers close to the militants. According to prosecutors, he was briefly a correspondent for a Hezbollah media outlet in 2017 and was tasked with coordinating building work at a mosque. Germany is a staunch ally of Israel. It is also home to a Lebanese immigrant community of more than 100,000. BEIRUT — The Lebanese army is looking for more recruits as it beefs up its presence in southern Lebanon after the Israel-Hezbollah ceasefire. Lebanon’s army is a respected national institution that kept to the sidelines during the nearly 14-month conflict. During an initial 60-day truce, thousands of Lebanese troops are supposed to deploy in southern Lebanon, where U.N. peacekeepers also have a presence. Hezbollah militants are to pull back from areas near the border as Israel withdraws its ground forces. The army said those interested in joining up have a one-month period to apply, starting Tuesday. The Lebanese army has about 80,000 troops, with around 5,000 of them deployed in the south. DAMASCUS, Syria — Syria’s state news agency says a drone strike hit a car in a suburb of the capital, Damascus, killing one person. The agency did not give further details or say who was killed. It said the attack occurred Tuesday on the road leading to the Damascus International Airport south of the city. The area is known to be home to members of Iran-backed militant groups. Israel is believed to have carried out a number of strikes in the area in recent months as it has battled Iran-backed Hezbollah in neighboring Lebanon. Israeli officials rarely acknowledge such strikes. JERUSALEM — Israel’s defense minister warned that if the shaky ceasefire with Hezbollah collapses, Israel will widen its strikes and target the Lebanese state itself. He spoke the day after Israel carried out a wave of airstrikes that killed nearly a dozen people. Those strikes came after the Lebanese militant group fired a volley of projectiles as a warning over what it said were previous Israeli violations. Speaking to troops on the northern border Tuesday, Defense Minister Israel Katz said any violations of the agreement would be met with “a maximum response and zero tolerance.” He said if the war resumes, Israel will widen its strikes beyond the areas where Hezbollah’s activities are concentrated, and “there will no longer be an exemption for the state of Lebanon.” During the 14-month conflict between Israel and Hezbollah, which came to an end last week with a ceasefire brokered by the United States and France, Israel largely refrained from striking critical infrastructure or the Lebanese armed forces, who kept to the sidelines . When Israeli strikes killed or wounded Lebanese soldiers, the Israeli military said it was accidental . The ceasefire agreement that took effect last week gives 60 days for Israel to withdraw its forces from Lebanon and for Hezbollah militants to relocate north of the Litani River. The buffer zone is to be patrolled by Lebanese armed forces and U.N. peacekeepers. Israel has carried out multiple strikes in recent days in response to what it says are violations by Hezbollah. Lebanon’s parliament speaker, Nabih Berri, accused Israel of violating the truce more than 50 times in recent days by launching airstrikes, demolishing homes near the border and violating Lebanon’s airspace. Berri, a Hezbollah ally, had helped mediate the ceasefire. JERUSALEM — Palestinian officials say an Israeli airstrike in the northern West Bank has killed two Palestinians. Israel’s military said it struck a militant cell near the town of Al-Aqaba, in the Jordan Valley. It did not immediately give more details. The Palestinian Health Ministry confirmed the two deaths and said a third person was moderately wounded. About 800 Palestinians have been killed by Israeli fire in the West Bank since Hamas’ Oct. 7, 2023 attack out of Gaza ignited the war there. Israel has carried out near-daily military raids in the West Bank that it says are aimed at preventing attacks on Israelis, which have also been on the rise. Israel captured the West Bank, the Gaza Strip and east Jerusalem in the 1967 Mideast war. The Palestinians want all three territories for an independent state. BEIRUT — Iran’s ambassador to Lebanon made his first public appearance in Beirut since he was wounded in an attack involving exploding pagers in mid-September. Mojtaba Amani, who returned to Lebanon over the weekend after undergoing treatment in Iran, visited on Tuesday the scene south of Beirut where Hezbollah leader Hassan Nasrallah was killed in an Israeli airstrike on Sept. 27. Speaking about the airstrike that destroyed six buildings and killed Nasrallah and others, Amani said Israel should get for its act “the highest medal for sabotage, terrorism, blood and killing civilians.” Amani suffered serious injuries in his face and hands when a pager he was holding exploded in mid-September. The device was one of about 3,000 pagers that exploded simultaneously, killing and wounding many Hezbollah members. A day after the pager attack, a similar attack struck walkie-talkies. In total, the explosions killed at least 37 people and wounded more than 3,000, many of them civilians. Last month, a spokesperson for the office of Israel’s Prime Minister Benjamin Netanyahu said the pager attack was approved by Netanyahu.The AP Top 25 college football poll is back every week throughout the season! Get the poll delivered straight to your inbox with AP Top 25 Poll Alerts. Sign up here . DELAND, Fla. (AP) — Luke Bailey threw for 204 yards and three touchdowns with only five incompletions and Drake eased by Stetson 49-10 on Saturday to secure a second straight outright Pioneer Football League title. Davion Cherwin rushed for 161 yards on 11 carries and scored two times for Drake. Jun Ahn and Luke Woodson also had rushing scores. Cherwin scored a 91-yard touchdown, the longest run in the PFL this season, to make it 21-7 early in the second quarter. Kemani Wilson made a diving interception at the Drake 25-yard line with just over two minutes left in the first half and seven plays later, Bailey found Hunter Johnson for a 24-yard touchdown to make it 28-10 at halftime. Drake defensive lineman Finn Claypool forced a fumble on the third play of the second half and his teammate recovered it. Then Bailey lofted a pass to Jaxon Laminack for a touchdown and a 35-10 lead. Drake (8-2, 7-1) was coming off a 29-20 loss to Morehead State to end a 17-game PFL winning streak — the longest active conference winning streak in the FCS. Stetson (2-9, 0-7) quarterback Brady Meitz was intercepted three times and Matt O’Connor had one of his four pass attempts intercepted. ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballsuper ace wild 。

NORAD's Santa tracker was Cold War morale boost. Now it attracts millions of kids'What are we doing': Zachary City Council considers restriction on residential developmentVERNON Kay has NEVER been asked to compete on Strictly Come Dancing in 20 years - despite being married to the host. The BBC Radio Two presenter says he's been missed off the wish list by BBC executives since its launch in 2004. Tess Daly co-hosted the show with Bruce Forsyth until 2013 before taking over his role alongside Claudia Winkleman . Despite this, Vernon has never been called up to be asked to appear on the dance show that's on most celebrities' bucket lists. Instead he will watch from home or in the audience at Elstree Studios where Strictly in filmed. Speaking exclusively to The Sun as part of EE's campaign to improve Christmas with its latest tech upgrade WiFi 7 technology, Vernon Kay told us: "If they asked me, I'd think about it - and then I'd say no. "Let's be honest, it's been 20 bloody years and I've still not had a phone call. "It's like, I'm right here! Hello! "Every now and then I'll bump into the BBC executives at Broadcasting House, so I think it's time I say 'hello, remember me'." The 50-year-old backed Chris McCausland to win before he became the first blind contestant to hold the glitterball trophy. Vernon said: "I think Dianne has been an absolute saint in the way she's allowed people to realise that you know having a disability isn't the be all end all. "Chris has done absolutely amazingly and Dianne had everyone in tears in the semi-final when she said, look, Chris hasn't seen other people dance. "He hasn't seen what he's accomplished, what he's achieved. He hasn't seen his own hand placement or footwork. "It just struck a cord and touched everyone in the studio. Tess was in tears and she had to really fight back tears when she did the next link to introduce the next dancer. "I think it just summed up everything Chris has achieved. "That's what Strictly is all about. Watching it makes you feel good. "When you strip it down, it's about dancing. Dancing is difficult, but when it's done well it looks amazing."

The 2024 season hasn’t finished. There are still conference championship games to play, an expanded College Football Playoff to look forward to and bowl season in the near future. However, the first important date for the 2025 season is here. “Signing day is the fourth, portal opens on the ninth,” coach Jedd Fisch said on Nov. 25. "I'm sure there's going to be a ton of discussions, and at that point in time we can really visit what it's going to look like in the future, what's the 2025 calendar year going to look like and what's this team going to look like moving forward." Fisch and the Huskies will have their first chance to sign high school recruits for the 2025 season when the three-day early signing period begins on Wednesday. Washington currently holds commitments from 28 high school football players from across the country, and 247Sports composite ratings ranks UW’s 2025 recruiting class No. 19 nationally. UW has 16 offensive recruits, 11 defensive prospects and one specialist committed. California is home to 11 of them, five are from Washington, three from Oregon, two from Arizona, while Alabama, Florida, Hawaii, Illinois, Maryland, North Dakota and Texas each have one representative. The Division I Council previously voted to eliminate the 25-player limit on football recruiting classes on Oct. 4, 2023. The limit was initially suspended for two years starting in 2021 because of questions surrounding the COVID-19 pandemic. Of course, this signing period is almost three weeks earlier than its past iterations. The Collegiate Commissioners Association, which oversees and administers the National Letter of Intent program, announced the change back in March. The early signing period was initially introduced in 2017. Moving the early signing period forward helped reduce the stress of an overcrowded December recruiting calendar. During the past few seasons, the early signing period and the transfer portal overlapped. This year, however, the early signing period will end on Friday, while the portal won’t officially open until Dec. 9. New dates aren’t the only changes to the early signing period. In October, the NCAA Division I Council announced the elimination of the NLI program, which was first established in 1964. Instead, high school recruits will sign aid agreements on Wednesday, which serve a similar purpose. The agreements bind players to their chosen school unless they officially enter the transfer portal, while also prohibiting recruitment communications with other programs. They also may contain contracts for revenue sharing, which the House v. NCAA settlement allows starting next season. Fifth-year linebacker Carson Bruener and junior running back Jonah Coleman earned third-team All-Big Ten honors when the conference announced its end-of-season awards on Tuesday. Bruener was a consensus selection by the coaches and the media. The Woodinville native and UW captain has 93 tackles, two tackles for a loss, a forced fumble, three interceptions, and five pass breakups during his final season in purple and gold. Bruener was an All-Pac-12 honorable mention in 2023. Coleman, who was chosen by the media, has 1,011 yards on 184 carries and 10 touchdowns in his debut season with Washington. He’s averaging 5.5 yards per attempt and 84.3 rushing yards per game. Coleman, who was an All-Pac-12 honorable mention at Arizona in 2023, also has 22 catches for 170 yards. The Big Ten coaches chose Ohio State’s TreVeyon Henderson instead of Coleman for the third-team running back spot, choosing the Washington running back as an honorable mention instead. Additionally, sophomore wide receiver Denzel Boston was a consensus All-Big Ten honorable mention. The coaches also selected senior tight end Keleki Latu, sixth-year linebacker Alphonzo Tuputala, senior defensive tackle Sebastian Valdez and senior cornerback Thaddeus Dixon as All-Big Ten honorable mentions. Oregon quarterback Dillon Gabriel was named the conference’s offensive player of the year, while Penn State edge rusher Abdul Carter was the defensive player of the year. Ohio State’s Jeremiah Smith earned freshman of the year honors while Indiana’s Curt Cignetti was named coach of the year by both the coaches and the media. Washington endured its second transfer portal defection on Tuesday, as junior edge rusher Maurice Heims announced he will depart the team after four years on Montlake. “Thank you for making the last four years here some of the best of my life,” Heims wrote in a post on his social media accounts. Heims, a 6-foot-5, 263-pound pass rusher from Hamburg, Germany, played in 30 games at Washington after arriving before the 2021 season. He registered nine tackles, two tackles for a loss and one sack. Heims was mostly a special-teams player this season. He has one season of eligibility remaining. “As a kid from Hamburg, Germany that was completely new to this beautiful sport and this city, you have made every moment amazing,” Heims wrote. “Whether win or loss, y’all have always had our back and you are what makes this place truly special.”Middle East latest: Israeli strikes on Gaza hospital wound 3, Netanyahu vows 'iron fist' in Lebanon

Crizanlizumab by Novartis for Chronic Kidney Disease (Chronic Renal Failure): Likelihood of ApprovalSilicon Valley minimum wage bump barely makes a dentThe Phase 1b trial (NCT05351502) is a clinical proof-of-concept trial that will assess the intratumoral administration of LV UNO in patients with unresectable cutaneous or subcutaneous histologically confirmed primary or metastatic lesions, who have shown disease progression or prolonged stable disease (≥ 12 weeks) after receiving a single agent anti-PD-1 containing treatment. The trial, which is expected to enroll up to 20 subjects, is designed to assess the preliminary efficacy of LV UNO by objective response rate (ORR) and duration of response (DOR) per RECIST v1.1 and secondarily immune-related response via iRECIST. Safety and tolerability of LV UNO in combination with anti-PD-1 therapy, as well as its potential to enhance the type, density, and distribution of immune cells within the tumor microenvironment will also be observed. Topline data from the Phase 1b portion of the study are anticipated in the second half of 2025. "We are excited to initiate the Phase 1b trial of LV UNO, a potentially groundbreaking solid tumor treatment approach, in combination with PD-1 inhibitors,” said Dr. Jedidiah Monson, Chief Medical Officer of Beyond Cancer. "In preclinical studies, a single dose of UNO has been shown to increase PD-L1 expression and improve overall survival in animal models compared to anti-PD-1 alone. Further, Phase 1a human data that demonstrated immune system activation were presented at ASCO's Key Opinion Leader Event held in June 2024. We look forward to the Phase 1b trial results to establish the basis of further investigation of UNO in combination with PD-1 inhibitors.” "The initiation of the Phase 1b trial represents a major step forward in our vision for personalized cancer treatment. We see UNO as a complementary therapy for future cancer treatment paradigms, particularly for patients with anti-PD-1 refractory or resistant disease, potentially offering more patients access to effective treatment,” stated Dr. Selena Chaisson, Chief Executive Officer, and Director of Beyond Cancer. About Nitric Oxide Nitric Oxide (NO) is a potent molecule, naturally synthesized in the human body, proven to play a critical role in a broad array of biological functions. In the airways, NO targets the vascular smooth muscle cells that surround the small resistance arteries in the lungs. Currently, exogenous inhaled NO is used in adult respiratory distress syndrome, post certain cardiac surgeries and persistent pulmonary hypertension of the newborn to treat hypoxemia. Additionally, NO is believed to play a key role in the innate immune system and in vitro studies suggest that NO possesses anti-microbial activity not only against common bacteria, including both gram-positive and gram-negative, but also against other diverse pathogens. About UNO Therapy for Solid Tumors Cancer is the second leading cause of death globally, with tumor metastases responsible for approximately 90% of all cancer-related deaths. Current cancer treatment modalities generally include chemotherapy, immunotherapy, radiation, and/or surgery. Ultra-high concentration Nitric Oxide (UNO) therapy is a completely new approach to preventing relapse or metastatic disease. In vitro murine data show that local tumor ablation with UNO stimulates an anti-tumor immune response in solid tumor cancer models. Beyond Cancer, Ltd. believes that UNO has the potential to prevent relapse or metastatic disease with as little as a single 5-minute treatment and with limited toxicity or off-target effects. About Beyond Cancer, Ltd. Beyond Cancer, Ltd. is a development-stage biopharmaceutical and medical device company utilizing ultra-high concentration nitric oxide (UNO) via a proprietary delivery platform to treat primary tumors and prevent metastatic disease. Nitric oxide at ultra-high concentrations has been reported to show anticancer properties and to potentially serve as a chemosensitizer and radiotherapy enhancer. A first-in-human study is underway in patients with solid tumors. Beyond Cancer is also conducting preclinical studies of UNO in multiple solid tumor models to inform additional treatment protocols. For more information, visit www.beyondcancer.com . Forward Looking Statements This press release contains "forward-looking statements” concerning the potential safety and efficacy of inhaled nitric oxide and the ultra-high concentration nitric oxide product candidate, as well as its therapeutic potential in a number of indications; and the potential impact on patients and anticipated benefits associated with inhaled nitric oxide and the ultra-high concentration nitric oxide product candidate. Forward-looking statements include statements about expectations, beliefs, or intentions regarding product offerings, business, results of operations, strategies or prospects. You can identify such forward-looking statements by the words "expects,” "plans,” "anticipates,” "believes” "expects,” "intends,” "looks forward,” "projects,” "goal,” "assumes,” "targets” and similar expressions and/or the use of future tense or conditional constructions (such as "will,” "may,” "could,” "should” and the like) and by the fact that these statements do not relate strictly to historical or current matters. Rather, forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to risks and uncertainties that could cause actual results to differ materially from any future results expressed or implied by the forward-looking statements. These forward-looking statements are only predictions and reflect views as of the date they are made with respect to future events and financial performance. Many factors could cause actual activities or results to differ materially from the activities and results anticipated in forward-looking statements, including risks related to the ability to raise additional capital; the timing and results of future pre-clinical studies and clinical trials concerning the ultra-high concentration nitric oxide product candidate; the potential that regulatory authorities, including the FDA and comparable non-U.S. regulatory authorities, may not grant or may delay approval for the ultra-high concentration nitric oxide product candidate; the approach to discover and develop novel drugs, which is unproven and may never lead to efficacious or marketable products; obtaining, maintaining and protecting intellectual property utilized by products; competition from others using similar technology and others developing products for similar uses; dependence on collaborators; and other risks, which may, in part, be identified and described in the "Risk Factors” section of Beyond Air, Inc.'s most recent Annual Report on Form 10-K and other of its filings with the Securities and Exchange Commission, all of which are available on Beyond Air, Inc.'s website. Beyond Cancer and Beyond Air undertake no obligation to update, and have no policy of updating or revising, these forward-looking statements, except as required by applicable law. CONTACTS: Corey Davis, PhD LifeSci Advisors, LLC [email protected] (212) 915-2577 Matt Johnson, Head of Corporate Development & Strategy Beyond Cancer, Ltd. [email protected]The intricate world of semiconductors has turned into a battleground for global influence, with China striving to assert its own might against Western dominance. Amid increasing U.S. pressures , China has unveiled a monumental plan, pouring $41 billion into its lithography sector to bolster its semiconductor capabilities. China’s ambition to become technologically independent is manifesting through strategic investments in its semiconductor industry, a journey it embarked on back in 2014. Spearheading these efforts is SMIC (Semiconductor Manufacturing International Corporation). This Chinese giant grapples with competing against ASML, the Dutch leader with a stronghold on cutting-edge photolithography technology. Photolithography is pivotal in cutting-edge chip production, and ASML’s EUV (Extreme Ultraviolet) equipment is crucial for creating chips at the extremely fine scale of 3 nanometers. Despite facing export curbs backed by the U.S., which significantly hampers China’s access to such advanced machinery, Beijing remains undeterred. Focusing on technology giants like SMIC, Hua Hong Semiconductor, Naura Technology Group, and Advanced Micro-Fabrication Equipment, China’s massive financial injection aims to develop its own advanced alternatives to ASML’s tools, though this endeavor is fraught with technical and time-related challenges. Last year, the debut of Huawei’s Mate 60 Pro, a smartphone boasting a domestically-made 5G processor, marked a symbolic victory for China against harsh international sanctions. However, as ASML accelerates toward its High-NA EUV systems, the next frontier in chip technology, the West continues to safeguard its technological lead. This clash over chip supremacy holds wide-reaching implications, influencing not only technological progress but also strategic autonomy and geopolitical power. The question remains whether China’s relentless investment can truly shift the balance of power in the semiconductor industry. Inside China’s Billion-Dollar Semiconductor Strategy: Can It Challenge Western Dominance? The global semiconductor industry is witnessing a significant tectonic shift as China intensifies efforts to boost its technological prowess against Western strongholds. With an ambitious push to achieve technological independence, China has announced an impressive $41 billion investment directed at its lithography sector, marking a serious commitment to strengthening its semiconductor capabilities. China’s Strategic Investment Path The push toward technological sovereignty has been a long-term goal for China, initially setting the wheels in motion in 2014. Leading the charge is SMIC (Semiconductor Manufacturing International Corporation), which faces formidable Western competitors like ASML, renowned for its cutting-edge photolithography technology essential for high-precision chip production. With photolithography playing a pivotal role in producing state-of-the-art chips, China’s quest to develop domestic alternatives to ASML’s EUV (Extreme Ultraviolet) technology is both strategic and challenging. Emerging Trends and Innovations China’s advancement in semiconductor capabilities is not just a matter of keeping pace with Western technology but also involves spurring innovation within its borders. Companies like Hua Hong Semiconductor, Naura Technology Group, and Advanced Micro-Fabrication Equipment are at the forefront of these efforts. Through this substantial financial injection, China aims to achieve milestones that could revolutionize its semiconductor industry, although the path is laden with technical and time-related hurdles. Pros and Cons of China’s Semiconductor Ambition – Pros: – Technological Sovereignty: Breaking free from Western technology dependency enhances China’s strategic autonomy. – Industrial Growth: Bolstering the semiconductor industry could lead to job creation and economic growth. – Innovation Drive: Encourages local innovation which might drive new technological breakthroughs. – Cons: – Export Curbs: Restrictions from the U.S. and its allies pose significant barriers to accessing the latest technology. – Technical Challenges: Developing alternatives to established technologies is both costly and time-consuming. – Global Tensions: Increasing focus on self-sufficiency could escalate geopolitical tensions, impacting international trade relations. Market and Technology Predictions The semiconductor arena is poised for transformative changes. While China’s relentless investment may not immediately dethrone Western dominance, it could lead to a more competitive, diverse, and dynamic market. A notable breakthrough in China’s lithography capabilities could potentially recalibrate the balance of power in global chip production. As Huawei’s Mate 60 Pro smartphone demonstrated, which featured a domestically-made 5G processor, there are signs of China’s growing confidence in overcoming international sanctions. Meanwhile, Western companies like ASML remain committed to advancing frontier technologies with their next-generation High-NA EUV systems, maintaining a technological lead in the immediate future. Security and Sustainability Aspects Increased self-reliance in semiconductor production not only strengthens national security but also encourages sustainable industry practices. By focusing on homegrown production, China potentially reduces the carbon footprint associated with global shipping and logistics of semiconductor components. Conclusion: The Path Ahead The semiconductor sector remains a battleground in the broader struggle for global technological leadership. Despite numerous challenges, China’s strategic approach and hefty investments signal a determined advance toward reshaping the semiconductor industry landscape. While the outcome of this investment remains to be seen, the possibility of China emerging as a formidable force in the semiconductor domain cannot be ignored. Readers interested in further information on this topic may explore leading technology analysis platforms or authoritative sources such as ASML and SMIC .

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Tech cooperation to continue under Trump govt: HuangAP Business SummaryBrief at 5:43 p.m. EST