lucky 88

Sowei 2025-01-12
Acoltremon is under clinical development by and currently in Phase III for Keratoconjunctivitis Sicca (Dry Eye). According to GlobalData, Phase III drugs for Keratoconjunctivitis Sicca (Dry Eye) have a 26% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. Acoltremon overview Acoltremon (AR-15512) is under development for the treatment of dry eye syndrome. It is administered through ophthalmic route as a solution. It acts by targeting TRPM8 receptor. It was also under development for vaginal dryness. Alcon overview is engaged in the development and manufacturing of devices in the field of ophthalmology. The company’s portfolio encompasses contact lenses and surgical products, including implantables, consumables and surgical equipment. The company’s products are indicated for the treatment of various conditions such as cataracts, glaucoma, retinal diseases and refractive errors. It conducts clinical trials to evaluate the safety and efficacy of its products for the prevention and cure of blindness and different eye diseases. ’s pipeline products are developed through collaboration with institutions, medical innovators, research advisors and academic thought leaders. The company has operations in the Americas, Europe, the Middle East, and Africa and Asia Pacific. is headquartered in Fribourg, Switzerland. For a complete picture of Acoltremon’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .lucky 88

NoneWASHINGTON (AP) — Special counsel Jack Smith moved to abandon two criminal cases against Donald Trump on Monday, acknowledging that Trump’s return to the White House will preclude attempts to federally prosecute him for retaining classified documents or trying to overturn his 2020 election defeat. The decision was inevitable, since longstanding Justice Department policy says sitting presidents cannot face criminal prosecution. Yet it was still a momentous finale to an unprecedented chapter in political and law enforcement history, as federal officials attempted to hold accountable a former president while he was simultaneously running for another term. In court filings, Smith's team emphasized that the move to abandon their prosecutions was not a reflection of the merit of the cases but a recognition of the legal shield that surrounds any commander in chief. “That prohibition is categorical and does not turn on the gravity of the crimes charged, the strength of the Government’s proof, or the merits of the prosecution, which the Government stands fully behind,” the prosecutors wrote in one of their filings. Smith’s team said it was leaving intact charges against two co-defendants in the classified documents case — Trump valet Walt Nauta and Mar-a-Lago property manager Carlos De Oliveira — because “no principle of temporary immunity applies to them.” Steven Cheung, Trump's incoming White House communications director, welcomed the decision to drop the prosecutions against the president-elect, describing it as a “major victory for the rule of law.” "The American People and President Trump want an immediate end to the political weaponization of our justice system and we look forward to uniting our country,” Cheung said in a statement. Trump has long described the investigations as politically motivated, and he has vowed to fire Smith as soon as he takes office in January. Now he will re-enter the White House free from criminal scrutiny by the government that he will lead. The election case brought last year was once seen as one of the most serious legal threats facing Trump as he tried to reclaim the White House. He was indicted for plotting to overturn his defeat to Joe Biden in 2020, an effort that climaxed with his supporters' violent attack on the U.S. Capitol on Jan. 6, 2021. But the case quickly stalled amid legal fighting over Trump’s sweeping claims of immunity from prosecution for acts he took while in the White House. The U.S. Supreme Court in July ruled for the first time that former presidents have broad immunity from prosecution, and sent the case back to U.S. District Judge Tanya Chutkan to determine which allegations in the indictment, if any, could proceed to trial. The case was just beginning to pick up steam again in the trial court in the weeks leading up to this year’s election. Smith’s team in October filed a lengthy brief laying out new evidence they planned to use against him at trial, accusing him of “resorting to crimes” in an increasingly desperate effort to overturn the will of voters after he lost to Biden. The separate case involving classified documents had been widely seen as legally clear cut, especially because the conduct in question occurred after Trump left the White House and lost the powers of the presidency. The indictment included dozens of felony counts accusing him of illegally hoarding classified records from his presidency at his Mar-a-Lago estate in Palm Beach, Florida, and obstructing federal efforts to get them back. He has pleaded not guilty and denied wrongdoing. The case quickly became snarled by delays, with U.S. District Judge Aileen Cannon slow to issue rulings — which favored Trump’s strategy of pushing off deadlines in all his criminal cases — while also entertaining defense motions and arguments that experts said other judges would have dispensed with without hearings. In May, she indefinitely canceled the trial date amid a series of unresolved legal issues before dismissing the case outright two months later. Smith’s team appealed the decision, but now has given up that effort. ___ Associated Press writer Colleen Long contributed to this story. Alanna Durkin Richer, Eric Tucker And Chris Megerian, The Associated Press



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Black plastic kitchen utensil risks were overstated. But you should still toss them, group saysWASHINGTON (AP) — Special counsel Jack Smith moved to abandon two criminal cases against Donald Trump on Monday, acknowledging that Trump’s return to the White House will preclude attempts to federally prosecute him for retaining classified documents or trying to overturn his 2020 election defeat. The decision was inevitable, since longstanding Justice Department policy says sitting presidents cannot face criminal prosecution. Yet it was still a momentous finale to an unprecedented chapter in political and law enforcement history, as federal officials attempted to hold accountable a former president while he was simultaneously running for another term. In court filings, Smith's team emphasized that the move to abandon their prosecutions was not a reflection of the merit of the cases but a recognition of the legal shield that surrounds any commander in chief. “That prohibition is categorical and does not turn on the gravity of the crimes charged, the strength of the Government’s proof, or the merits of the prosecution, which the Government stands fully behind,” the prosecutors wrote in one of their filings. Smith’s team said it was leaving intact charges against two co-defendants in the classified documents case — Trump valet Walt Nauta and Mar-a-Lago property manager Carlos De Oliveira — because “no principle of temporary immunity applies to them.” Steven Cheung, Trump's incoming White House communications director, welcomed the decision to drop the prosecutions against the president-elect, describing it as a “major victory for the rule of law.” "The American People and President Trump want an immediate end to the political weaponization of our justice system and we look forward to uniting our country,” Cheung said in a statement. Trump has long described the investigations as politically motivated, and he has vowed to fire Smith as soon as he takes office in January. Now he will re-enter the White House free from criminal scrutiny by the government that he will lead. The election case brought last year was once seen as one of the most serious legal threats facing Trump as he tried to reclaim the White House. He was indicted for plotting to overturn his defeat to Joe Biden in 2020, an effort that climaxed with his supporters' violent attack on the U.S. Capitol on Jan. 6, 2021. But the case quickly stalled amid legal fighting over Trump’s sweeping claims of immunity from prosecution for acts he took while in the White House. The U.S. Supreme Court in July ruled for the first time that former presidents have broad immunity from prosecution, and sent the case back to U.S. District Judge Tanya Chutkan to determine which allegations in the indictment, if any, could proceed to trial. The case was just beginning to pick up steam again in the trial court in the weeks leading up to this year’s election. Smith’s team in October filed a lengthy brief laying out new evidence they planned to use against him at trial, accusing him of “resorting to crimes” in an increasingly desperate effort to overturn the will of voters after he lost to Biden. The separate case involving classified documents had been widely seen as legally clear cut, especially because the conduct in question occurred after Trump left the White House and lost the powers of the presidency. The indictment included dozens of felony counts accusing him of illegally hoarding classified records from his presidency at his Mar-a-Lago estate in Palm Beach, Florida, and obstructing federal efforts to get them back. He has pleaded not guilty and denied wrongdoing. The case quickly became snarled by delays, with U.S. District Judge Aileen Cannon slow to issue rulings — which favored Trump’s strategy of pushing off deadlines in all his criminal cases — while also entertaining defense motions and arguments that experts said other judges would have dispensed with without hearings. In May, she indefinitely canceled the trial date amid a series of unresolved legal issues before dismissing the case outright two months later. Smith’s team appealed the decision, but now has given up that effort. ___ Associated Press writer Colleen Long contributed to this story. Alanna Durkin Richer, Eric Tucker And Chris Megerian, The Associated Press

AP Business SummaryBrief at 11:21 a.m. ESTMovate Emerges as Leader in Digital Workplace Services 2024HUMBOLDT, Tenn. (AP) — A Tennessee man was convicted Thursday of killing two men and wounding a third in a shooting at a high school basketball game three years ago. Jadon Hardiman, 21, was found guilty in Gibson County of charges including second-degree murder, attempted murder, aggravated assault and weapons offenses, district attorney Frederick Agee said in a statement. He faces up to 76 years in prison at sentencing in April. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get updates and player profiles ahead of Friday's high school games, plus a recap Saturday with stories, photos, video Frequency: Seasonal Twice a week

Children’s Minister Roderic O’Gorman said the party could not buck the trend in Ireland of junior coalition partners in Fine Gael and Fianna Fail governments losing support in subsequent elections. He said they expected to retain two to three seats out of the 12 they had won in the 2020 election on the back of a worldwide “Green wave”. “Undoubtedly it’s a disappointing result for our party today,” Mr O’Gorman told reporters in Ongar, Dublin. “It’s hard for a smaller party in government, that’s long been the tradition, the history in Ireland. We hoped going into the election to buck that but we haven’t been able to buck that today.” Mr O’Gorman, a candidate in Dublin West, is among the outgoing Green Party TDs in a battle to retain their seats. Culture Minister Catherine Martin, who is fighting to remain a Green Party TD for Dublin Rathdown, said it was a “very tight” race in her four-seat constituency. “We go in (to government) not afraid of that because the issue of the climate and biodiversity crisis is (greater) than our survival,” she said on RTE Radio. “I stand over and am proud of our track record of delivery.” Green candidate in Waterford Marc O Cathasaigh said he would not be “in the shake-up” to retain his seat in that constituency, while junior minister Ossian Smyth looks at risk of losing his seat in Dun Laoghaire. Junior minister Joe O’Brien is expected to lose his seat in Dublin Fingal, Neasa Hourigan is at risk in Dublin Central, while Wicklow’s Steven Matthews garnered just 4% of first preferences. Former Green Party leader Eamon Ryan, who announced his retirement from frontline politics in June, said his party had not had a good day. Arriving at the count centre at the RDS in Dublin, the outgoing environment minister told reporters: “If you don’t get elected you accept that, but you come back stronger and you learn lessons, and we’ve done that in the past and we will do that again.” He added: “No matter what the results today there will be a strong Green Party in Ireland, we have deep roots in the community and it’s a very distinct political philosophy and I think there is still space for that in Irish politics, for sure.” Mr Ryan said he did not believe his decision to retire, and the timing of his announcement, had affected the party’s showing. “Unfortunately – and this is just one of those days – we didn’t get the number of votes,” he said. He added: “We’ll look back and see what are the lessons, and what can we learn and what can we do differently. “It’s just one of those days when we didn’t have a good day.A recent study that recommended toxic chemicals in black plastic products be immediately thrown away included a math error that significantly overstated the risks of contamination, but its authors are standing by their conclusions and warn against using such products. Published in the peer-reviewed journal Chemosphere , experts from the nonprofit Toxic-Free Future said they detected flame retardants and other toxic chemicals in 85% of 203 items made of black plastic including kitchen utensils , take-out containers, children's toys and hair accessories. In a blog post, Joe Schwarcz, director of McGill University's Office for Science and Society in Canada, explained that the Toxin-Free Future scientists miscalculated the lower end of what the EPA considered a health risk through a multiplication error. Instead of humans being potentially exposed to a dose of toxic chemicals in black plastic utensils near the minimum level that the EPA deems a health risk, it's actually about one-tenth of that. (Dreamstime/TNS) The study initially said the potential exposure to chemicals found in one of the kitchen utensils approached the minimum levels the Environmental Protection Agency deemed a health risk. But in an update to the study, the authors say they made an error in their calculations and the real levels were "an order of magnitude lower" than the EPA's thresholds. The error was discovered by Joe Schwarcz, director of McGill University's Office for Science and Society in Canada. In a blog post, Schwarcz explained that the Toxin-Free Future scientists miscalculated the lower end of what the EPA considered a health risk through a multiplication error. Instead of humans being potentially exposed to a dose of toxic chemicals in black plastic utensils near the minimum level that the EPA deems a health risk, it's actually about one-tenth of that. Though Schwarcz said the risks outlined in the study aren't enough for him to discard his black plastic kitchen items if he had them, he agreed with the authors that flame retardants shouldn't be in these products in the first place. "The math error does not impact the study's findings, conclusions or recommendations," said Megan Liu, a co-author of the study who is the science and policy manager for Toxic-Free Future . She added that any traces of flame retardants or toxic chemicals in cooking utensils should be concerning for the public. Flame retardants are getting into commonly used items because black-colored products are being made from recycled electronic waste, such as discarded television sets and computers, that frequently contain the additives. When they're heated, the flame retardants and other toxic chemicals can migrate out. If you're wondering whether your old black plastic spoon or other utensils are a part of this group, Liu shared some more guidance. It's nearly impossible to know whether a black plastic product is contaminated. That's because these products that include recycled e-waste don't disclose a detailed list of all ingredients and contaminants in the product. Liu said it's also unclear how many types of flame retardants are in these black plastic products. Some of the products that researchers tested in this recent study "had up to nine different harmful chemicals and harmful flame retardants in them," she said. Anytime you're looking for the type of recycled plastic a product is made of you're going to look for a number within the chasing arrows (that form a triangle) logo. Recycling symbols are numbered 1 to 7 and we commonly associate the numbers with what we can toss in our blue recycling bins. The 1 through 7 numbers stand for, respectively, polyethylene terephthalate, high-density polyethylene, polyvinyl chloride (PVC), low-density polyethylene, polypropylene, polystyrene or Styrofoam, and miscellaneous plastics (including polycarbonate, polylactide, acrylic, acrylonitrile butadiene, styrene, fiberglass and nylon). The study found higher levels of toxic flame retardants in polystyrene plastic, which is labeled with the number 6, said Liu. There isn't a definitive timeline of when recycled electronic-waste started to be incorporated into black plastic products specifically, but e-waste started to get recycled in the early 2000s, Liu said. The way computers, cellphones, stereos, printers and copiers were being disposed of previously was to simply add them to a landfill without reusing salvageable parts. But as the National Conference of State Legislatures notes, electronics production required a significant amount of resources that could be recovered through recycling. Recovering resources such as metals, plastics and glass through recycling used a fraction of the energy needed to mine new materials. However, the study pointed out that flame retardants and other chemical contaminates have been detected in and near e-waste recycling facilities, in indoor air and dust at formal e-waste recycling facilities in Canada, China, Spain and the U.S. It also noted contamination in soil samples surrounding e-waste recycling sites in China and Vietnam. The safest nontoxic material options for kitchen utensil are wood and stainless steel. The 20th century brought airplanes, radio, television, the internet, and plastic. Lots of plastic. That plastic is now showing up on shorelines, forming islands in oceans, and generating mountains of translucent trash on land. Around 700 species of animals in the sea have been found to interact with plastic daily. Companies across every industry face pressure to reduce the amount of plastic they produce. Seventy-two percent of the world's largest have made voluntary commitments to reduce their plastic waste, according to a Duke University analysis. One industry, in particular, has greatly benefited from advancements in single-use plastic technology: the medical industry. Only in recent years have businesses and academics in the field begun to talk about minimizing their impact on our environment like beverage manufacturers and other consumer goods-producing businesses. Medical Technology Schools analyzed academic studies published in the National Library of Medicine , the American Medical Association , and news reports to shed light on the medical community's use of plastics through history, their environmental problems, and proposed solutions to reduce their impact. And the impact can be significant. A single hospital patient generates nearly 34 pounds of waste a day —as much as a quarter of it is plastic. The COVID-19 pandemic only worsened the problem. The pandemic pushed hospital capacity to the brink and led to a massive increase in personal protective equipment and medical supply usage. Medical-grade masks and other protective equipment like face shields, made mostly of nonrenewable plastics, were in high demand. In 2020, the World Health Organization estimated that the international need for PPE manufacturing would boost 40% to address the public health crisis. Hospitals needed an estimated 89 million masks, 76 million gloves, and 1.6 million goggles every month of the pandemic. To date, nearly 677 million COVID-19 vaccine doses have been administered, each requiring their own plastic syringe, according to data from the Centers for Disease Control and Prevention. Global consulting firm Frost & Sullivan estimated that the U.S. would produce a year's worth of medical waste in just two months due to the pandemic. The World Economic Forum warned that the COVID-19 crisis threatened to " stall and even reverse progress " to reduce large plastic waste. It's a challenge researchers acknowledge today as they search for solutions. Plastics introduced an era of ultraconvenience to the world. It makes our clothes. It's made bike helmets and airbags possible. And it's a cheap material to produce, meaning it's cheap for consumers too. Almost as importantly, it's durable and incredibly easy to make into complex shapes—a trait that helped plastics invented in the mid-20th century quickly replace more expensive metal and wooden goods. That adoption extended to the medical field, where the single-use nature of plastics represented a move toward more hygienic tools for physicians and hospitals. But it wasn't plastic's sanitary qualities that the industry first latched onto. Like so many other technical advancements, convenience and cost were the initial driving factors. That they were more conducive to creating a sterile environment for patients was a benefit that health care began to tout closer to the end of the 20th century. PVC, or polyvinyl chloride, replaced glass bottles previously used to hold IV solution and replaced rubber tubing used throughout hospital settings. Plastic has also become the go-to material for making syringes and catheters. Plastic products are generally made from chemicals derived from the oil and natural gas refining process. Chemists use those byproducts to create synthetic materials with malleable and durable chemical structures. The low cost of these materials has helped medical device-makers support better health outcomes for communities across the U.S. since the 1900s. No longer was health care priced at rates only the elite could afford—it was accessible to a much larger swath of the public. In the last decade, the U.S., in particular, has emerged as a massive market for medical plastics. The country generally accounts for nearly half of the global market for medical devices. Plastic's durability is not only a benefit but a detriment to the environment, as the material can take many years to deteriorate when it enters landfills or trashes oceans. Estimates vary widely, but scientists ballpark that depending on the kind of plastic and the environment in which it decomposes, it could take dozens to thousands of years to break down entirely. COVID-19, which remains a burden for health care systems, isn't the only force raising the stakes for a health care industry pressured to reduce reliance on plastics or find ways to reuse them. Global annual production of plastic has doubled in the last two decades , according to the Environmental Protection Agency. As the U.S. looks toward the future, its aging population is another factor that could exacerbate the rate at which medical plastics end up in landfills. People require more medical care as they age, and aging baby boomers are expected to place increased demand on the medical device industry. At the same time, governments are under pressure to lower health care costs, which have become unaffordable even for those insured . As recently as 2021, researchers lamented a lack of data on efforts to recycle medical plastics. Around 350 hospitals participate in Practice Greenhealth's Environmental Excellence Awards . Practice Greenhealth is an organization working to help hospitals increase their sustainability. It's one of the few sources of hospital sustainability data, and its roster of participating hospitals represents a small fraction of the more than 6,000 hospitals operating in the U.S. To meet the need to reduce plastic waste generation, some hospitals are moving away from using plastic in certain applications. Ronald Reagan UCLA Medical Center replaced health care workers' disposable plastic isolation gowns with reusable cloth gowns at its hospitals in the last decade, saving money and preventing literal tons of medical waste. It also implemented a process for sterilizing and incinerating the boxes that hold used needles, allowing them to be reassembled and reused in a health care setting. Recycling plastic medical waste is complicated by the potential for contamination and the need to separate contaminated and noncontaminated waste; once separated, they can be broken down with heat or treated with chemicals and reprocessed. However, using chemical methods to break down and dispose of plastics has drawbacks. Over 200 nongovernmental organizations signed a letter in 2023 urging the Biden administration to end federal support for methods like these, arguing they generate toxic pollutants. The Vinyl Council of Australia is working with hospitals to recover used materials made of PVC . The materials are broken down into tiny pieces, washed and heated at high temperatures, and remade into things used outside medical settings. In the U.S. and Europe, there's the Healthcare Plastics Recycling Council, a coalition of companies working in the health care device space that includes DuPont, Johnson & Johnson, and Medtronic. In 2021, the HPRC, advised by professionals at Kaiser Permanente and other health systems, rolled out a medical waste recycling pilot project with hopes of scaling it across more hospitals. Story editing by Ashleigh Graf. Copy editing by Paris Close. Photo selection by Clarese Moller. This story originally appeared on Medical Technology Schools and was produced and distributed in partnership with Stacker Studio. Sign up here to get the latest health & fitness updates in your inbox every week!

From Toy Trains to Tablets: How Kids’ Christmas Gifts Changed Over 5 DecadesA recent study that recommended toxic chemicals in black plastic products be immediately thrown away included a math error that significantly overstated the risks of contamination, but its authors are standing by their conclusions and warn against using such products. Published in the peer-reviewed journal Chemosphere , experts from the nonprofit Toxic-Free Future said they detected flame retardants and other toxic chemicals in 85% of 203 items made of black plastic including kitchen utensils , take-out containers, children's toys and hair accessories. In a blog post, Joe Schwarcz, director of McGill University's Office for Science and Society in Canada, explained that the Toxin-Free Future scientists miscalculated the lower end of what the EPA considered a health risk through a multiplication error. Instead of humans being potentially exposed to a dose of toxic chemicals in black plastic utensils near the minimum level that the EPA deems a health risk, it's actually about one-tenth of that. (Dreamstime/TNS) The study initially said the potential exposure to chemicals found in one of the kitchen utensils approached the minimum levels the Environmental Protection Agency deemed a health risk. But in an update to the study, the authors say they made an error in their calculations and the real levels were "an order of magnitude lower" than the EPA's thresholds. The error was discovered by Joe Schwarcz, director of McGill University's Office for Science and Society in Canada. In a blog post, Schwarcz explained that the Toxin-Free Future scientists miscalculated the lower end of what the EPA considered a health risk through a multiplication error. Instead of humans being potentially exposed to a dose of toxic chemicals in black plastic utensils near the minimum level that the EPA deems a health risk, it's actually about one-tenth of that. Though Schwarcz said the risks outlined in the study aren't enough for him to discard his black plastic kitchen items if he had them, he agreed with the authors that flame retardants shouldn't be in these products in the first place. "The math error does not impact the study's findings, conclusions or recommendations," said Megan Liu, a co-author of the study who is the science and policy manager for Toxic-Free Future . She added that any traces of flame retardants or toxic chemicals in cooking utensils should be concerning for the public. Flame retardants are getting into commonly used items because black-colored products are being made from recycled electronic waste, such as discarded television sets and computers, that frequently contain the additives. When they're heated, the flame retardants and other toxic chemicals can migrate out. If you're wondering whether your old black plastic spoon or other utensils are a part of this group, Liu shared some more guidance. It's nearly impossible to know whether a black plastic product is contaminated. That's because these products that include recycled e-waste don't disclose a detailed list of all ingredients and contaminants in the product. Liu said it's also unclear how many types of flame retardants are in these black plastic products. Some of the products that researchers tested in this recent study "had up to nine different harmful chemicals and harmful flame retardants in them," she said. Anytime you're looking for the type of recycled plastic a product is made of you're going to look for a number within the chasing arrows (that form a triangle) logo. Recycling symbols are numbered 1 to 7 and we commonly associate the numbers with what we can toss in our blue recycling bins. The 1 through 7 numbers stand for, respectively, polyethylene terephthalate, high-density polyethylene, polyvinyl chloride (PVC), low-density polyethylene, polypropylene, polystyrene or Styrofoam, and miscellaneous plastics (including polycarbonate, polylactide, acrylic, acrylonitrile butadiene, styrene, fiberglass and nylon). The study found higher levels of toxic flame retardants in polystyrene plastic, which is labeled with the number 6, said Liu. There isn't a definitive timeline of when recycled electronic-waste started to be incorporated into black plastic products specifically, but e-waste started to get recycled in the early 2000s, Liu said. The way computers, cellphones, stereos, printers and copiers were being disposed of previously was to simply add them to a landfill without reusing salvageable parts. But as the National Conference of State Legislatures notes, electronics production required a significant amount of resources that could be recovered through recycling. Recovering resources such as metals, plastics and glass through recycling used a fraction of the energy needed to mine new materials. However, the study pointed out that flame retardants and other chemical contaminates have been detected in and near e-waste recycling facilities, in indoor air and dust at formal e-waste recycling facilities in Canada, China, Spain and the U.S. It also noted contamination in soil samples surrounding e-waste recycling sites in China and Vietnam. The safest nontoxic material options for kitchen utensil are wood and stainless steel. The 20th century brought airplanes, radio, television, the internet, and plastic. Lots of plastic. That plastic is now showing up on shorelines, forming islands in oceans, and generating mountains of translucent trash on land. Around 700 species of animals in the sea have been found to interact with plastic daily. Companies across every industry face pressure to reduce the amount of plastic they produce. Seventy-two percent of the world's largest have made voluntary commitments to reduce their plastic waste, according to a Duke University analysis. One industry, in particular, has greatly benefited from advancements in single-use plastic technology: the medical industry. Only in recent years have businesses and academics in the field begun to talk about minimizing their impact on our environment like beverage manufacturers and other consumer goods-producing businesses. Medical Technology Schools analyzed academic studies published in the National Library of Medicine , the American Medical Association , and news reports to shed light on the medical community's use of plastics through history, their environmental problems, and proposed solutions to reduce their impact. And the impact can be significant. A single hospital patient generates nearly 34 pounds of waste a day —as much as a quarter of it is plastic. The COVID-19 pandemic only worsened the problem. The pandemic pushed hospital capacity to the brink and led to a massive increase in personal protective equipment and medical supply usage. Medical-grade masks and other protective equipment like face shields, made mostly of nonrenewable plastics, were in high demand. In 2020, the World Health Organization estimated that the international need for PPE manufacturing would boost 40% to address the public health crisis. Hospitals needed an estimated 89 million masks, 76 million gloves, and 1.6 million goggles every month of the pandemic. To date, nearly 677 million COVID-19 vaccine doses have been administered, each requiring their own plastic syringe, according to data from the Centers for Disease Control and Prevention. Global consulting firm Frost & Sullivan estimated that the U.S. would produce a year's worth of medical waste in just two months due to the pandemic. The World Economic Forum warned that the COVID-19 crisis threatened to " stall and even reverse progress " to reduce large plastic waste. It's a challenge researchers acknowledge today as they search for solutions. Plastics introduced an era of ultraconvenience to the world. It makes our clothes. It's made bike helmets and airbags possible. And it's a cheap material to produce, meaning it's cheap for consumers too. Almost as importantly, it's durable and incredibly easy to make into complex shapes—a trait that helped plastics invented in the mid-20th century quickly replace more expensive metal and wooden goods. That adoption extended to the medical field, where the single-use nature of plastics represented a move toward more hygienic tools for physicians and hospitals. But it wasn't plastic's sanitary qualities that the industry first latched onto. Like so many other technical advancements, convenience and cost were the initial driving factors. That they were more conducive to creating a sterile environment for patients was a benefit that health care began to tout closer to the end of the 20th century. PVC, or polyvinyl chloride, replaced glass bottles previously used to hold IV solution and replaced rubber tubing used throughout hospital settings. Plastic has also become the go-to material for making syringes and catheters. Plastic products are generally made from chemicals derived from the oil and natural gas refining process. Chemists use those byproducts to create synthetic materials with malleable and durable chemical structures. The low cost of these materials has helped medical device-makers support better health outcomes for communities across the U.S. since the 1900s. No longer was health care priced at rates only the elite could afford—it was accessible to a much larger swath of the public. In the last decade, the U.S., in particular, has emerged as a massive market for medical plastics. The country generally accounts for nearly half of the global market for medical devices. Plastic's durability is not only a benefit but a detriment to the environment, as the material can take many years to deteriorate when it enters landfills or trashes oceans. Estimates vary widely, but scientists ballpark that depending on the kind of plastic and the environment in which it decomposes, it could take dozens to thousands of years to break down entirely. COVID-19, which remains a burden for health care systems, isn't the only force raising the stakes for a health care industry pressured to reduce reliance on plastics or find ways to reuse them. Global annual production of plastic has doubled in the last two decades , according to the Environmental Protection Agency. As the U.S. looks toward the future, its aging population is another factor that could exacerbate the rate at which medical plastics end up in landfills. People require more medical care as they age, and aging baby boomers are expected to place increased demand on the medical device industry. At the same time, governments are under pressure to lower health care costs, which have become unaffordable even for those insured . As recently as 2021, researchers lamented a lack of data on efforts to recycle medical plastics. Around 350 hospitals participate in Practice Greenhealth's Environmental Excellence Awards . Practice Greenhealth is an organization working to help hospitals increase their sustainability. It's one of the few sources of hospital sustainability data, and its roster of participating hospitals represents a small fraction of the more than 6,000 hospitals operating in the U.S. To meet the need to reduce plastic waste generation, some hospitals are moving away from using plastic in certain applications. Ronald Reagan UCLA Medical Center replaced health care workers' disposable plastic isolation gowns with reusable cloth gowns at its hospitals in the last decade, saving money and preventing literal tons of medical waste. It also implemented a process for sterilizing and incinerating the boxes that hold used needles, allowing them to be reassembled and reused in a health care setting. Recycling plastic medical waste is complicated by the potential for contamination and the need to separate contaminated and noncontaminated waste; once separated, they can be broken down with heat or treated with chemicals and reprocessed. However, using chemical methods to break down and dispose of plastics has drawbacks. Over 200 nongovernmental organizations signed a letter in 2023 urging the Biden administration to end federal support for methods like these, arguing they generate toxic pollutants. The Vinyl Council of Australia is working with hospitals to recover used materials made of PVC . The materials are broken down into tiny pieces, washed and heated at high temperatures, and remade into things used outside medical settings. In the U.S. and Europe, there's the Healthcare Plastics Recycling Council, a coalition of companies working in the health care device space that includes DuPont, Johnson & Johnson, and Medtronic. In 2021, the HPRC, advised by professionals at Kaiser Permanente and other health systems, rolled out a medical waste recycling pilot project with hopes of scaling it across more hospitals. Story editing by Ashleigh Graf. Copy editing by Paris Close. Photo selection by Clarese Moller. This story originally appeared on Medical Technology Schools and was produced and distributed in partnership with Stacker Studio. Sign up here to get the latest health & fitness updates in your inbox every week!Romania braces for parliamentary vote after far right's poll upset

KANSAS CITY, Mo. — Pick your adjective to describe the Kansas City Chiefs this season — charmed, serendipitous, fortunate or just plain lucky — and it probably fits, and not just because they keep winning games that come down to the wire. Every time they need help at a position, they've found someone sitting on the couch, seemingly waiting for their call. First it was wide receiver JuJu Smith-Schuster, who returned to the Chiefs just before the season after Marquise Brown was lost to shoulder surgery. Then it was running back Kareem Hunt, who likewise returned to his former team when Isiah Pacheco broke his fibula. Left tackle D.J. Humphries came next when other options at the position were struggling, and this week it was Steven Nelson, who came out of retirement to help a secondary that has struggled for weeks. "Just got an opportunity, got a call. Was very excited about it," said Nelson, who spent his first four seasons in Kansas City before stints in Pittsburgh and Houston, and ultimately calling it quits in June so he could spend more time with his family. "I've got two daughters and been spending a lot of time with him," Nelson said, "but still trying to work out. It was kind of the perfect scenario, getting the call, especially where this team has been and this point in the season. Great opportunity." It's been a perfect opportunity for all of them. Perfect fits for the Chiefs, too. Each could have signed just about anywhere else and been able to contribute, yet they were still sitting around when Chiefs general manager Brett Veach reached out. In the case of Smith-Schuster, Hunt and Humphries, there were some concerns about injuries that had kept some teams away, but the Chiefs were willing to take a risk on them. Smith-Schuster, who has dealt with knee trouble for years, missed some time with a hamstring injury this season. But he still has 202 yards and a touchdown receiving, and has provided some veteran leadership in the locker room. Hunt was coming off a sports hernia surgery, a big reason why the Browns — whom the Chiefs visit Sunday — declined to bring him back after five years spent in a one-two punch with Nick Chubb. But when Pacheco went down, Hunt stepped in and their offense barely missed a beat; he has run for a team-leading 608 yards and five touchdowns in 10 games. Humphries was still rehabbing a torn ACL at the start of the season, but the former Pro Bowl tackle was cleared just before the Chiefs called him. Kingsley Suamataia and Wanya Morris had struggled to protect Patrick Mahomes' blind side, so they brought in Humphries to help out. And while he hurt his hamstring late in his debut last week against the Chargers, the Chiefs still hope he'll be recovered and fully up to speed in time for the stretch run and the playoffs. "I'm in Kansas City, bro. I'm pretty ecstatic. It don't get much better than this," Humphries said. "Everybody is excited for me to be here and that's a really good feeling. You're getting All-Pro guys' arms outstretched, like, 'We're so glad you're here.'" The providential signings don't stop at those four players, either. When the Chiefs lost kicker Harrison Butker to knee surgery, they signed Spencer Shrader off the Jets practice squad, and he promptly kicked a game-winner against Carolina. But then Shrader hurt his hamstring and landed on injured reserve. The 49ers had just waived Matthew Wright, and the Chiefs signed him up. He's gone 8 for 9 on field-goal tries, has been perfect on PATs, and banged the game-winner off the upright and through last week against Los Angeles. Just like Smith-Schuster, Hunt and Nelson, Wright had been with Kansas City a couple of years ago. "It definitely helps, him knowing how we do things, how we practice and what we expect," Chiefs special teams coach Dave Toub said. "That all helped, for sure. And he's a veteran. He's been a lot of places. It wasn't like he was a rookie off the street." Or off the couch, for that matter. NOTES: Butker planned to kick again Thursday and could come off IR to face the Browns on Sunday. "He looked good," Toub said. "We have to see how he responds." ... Humphries (hamstring) did not practice Thursday. RT Jawaan Taylor (knee) was limited. ... SS Justin Reid will likely handle kickoffs against Cleveland. He has a stronger leg than Wright and also puts another athletic and adept tackler on the field on special teams. Get local news delivered to your inbox!Royal Caribbean director Arne Wilhelmsen sells $145.7 million in stock

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