VMT-01 is under clinical development by Perspective Therapeutics and currently in Phase II for Metastatic Melanoma. According to GlobalData, Phase II drugs for Metastatic Melanoma have a 36% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. VMT-01 overview VMT-01 is under development for the treatment of metastatic melanoma. The drug candidate is a MCR1-targeted radionuclide (90Y) therapy. therapy. It acts by targeting melanocyte stimulating hormone receptor (Melanocortin Receptor 1 or MSHR or MC1R). it is administered by intravenous route. Perspective Therapeutics overview Perspective Therapeutics, formerly known as Isoray, Inc., is a medical technology company. It specializes in the development and distribution of isotope-based personalized brachytherapy products and devices for advanced cancer treatments. The company’s core product is the Cesium-131 brachytherapy seed, a unique radioisotope seed used in the treatment of various cancers, including prostate, brain, head and neck, and lung cancers. Brachytherapy involves placing the radiation sources close to the tumor site to destroy the cancer cells. Perspective Therapeutics serves medical centers, hospitals, and clinics. It operates primarily in the US. Perspective Therapeutics is headquartered in Richland, Washington, the US. For a complete picture of VMT-01’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .LOS ANGELES (AP) — OpenAI CEO Sam Altman is planning to make a $1 million personal donation to President-Elect Donald Trump's inauguration fund, joining a number of tech companies and executives who are working to improve their relationships with the incoming administration. A spokesperson for OpenAI confirmed the move on Friday. The announcement comes one day after Meta, the parent company of Facebook and Instagram, said it donated $1 million to the same fund. Amazon also said it plans to donate $1 million. “President Trump will lead our country into the age of AI, and I am eager to support his efforts to ensure America stays ahead," Altman said in a statement. Altman, who is in a legal dispute with rival Elon Musk, has said he is “not that worried” about the Tesla CEO's influence in the incoming administration. Trump is putting Musk, the world’s richest man, and Vivek Ramaswamy , an entrepreneur and former Republican presidential candidate, in charge of the new Department of Government Efficiency, or DOGE, which is an outside advisory committee that will work with people inside the government to reduce spending and regulations. Musk, an early OpenAI investor and board member, sued the artificial intelligence company earlier this year alleging that the maker of ChatGPT betrayed its founding aims of benefiting the public good rather than pursuing profits. Musk recently escalated the lawsuit by asking a federal judge to stop OpenAI’s plans to convert itself into a for-profit business more fully. —— The Associated Press and OpenAI have a licensing and technology agreement allowing OpenAI access to part of the AP’s text archives.Which are the highest paying professions in Portugal?
(All times Eastern) Schedule subject to change and/or blackouts Thursday, Dec. 26 COLLEGE FOOTBALL 2 p.m. ESPN — The GameAbove Sports Bowl: Pittsburgh vs. Toledo, Detroit 5:30 p.m. ESPN — The Rate Bowl: Rutgers vs. Kansas St., Phoenix 9 p.m. ESPN — The 68 Ventures Bowl: Arkansas St. vs. Bowling Green, Mobile, Ala. IIHF HOCKEY (MEN’S) Noon NHLN — World Junior Championship Group Stage: Slovakia vs. Sweden, Group B, Toronto 2:30 p.m. NHLN — World Junior Championship Group Stage: U.S. vs. Germany, Group A, Ottawa, Ontario 5 p.m. NHLN — World Junior Championship Group Stage: Czechia vs. Switzerland, Group B, Toronto 7:30 p.m. NHLN — World Junior Championship Group Stage: Finland vs. Canada, Group A, Ottawa, Ontario NBA BASKETBALL 7 p.m. NBATV — Oklahoma City at Indiana 10 p.m. NBATV — Utah at Portland NFL FOOTBALL 8:15 p.m. PRIME VIDEO — Seattle at Chicago SOCCER (MEN’S) 7:30 a.m. USA — Premier League: Everton at Manchester City 9:55 a.m. CBSSN — EFL League One: Blackpool vs. Wrexham 10 a.m. USA — Premier League: Aston Villa at Newcastle United 12:30 p.m. USA — Premier League: Manchester United at Wolverhampton 12:40 p.m. CBSSN — SPFL: Rangers at St. Mirren 3 p.m. USA — Premier League: Leicester City at Liverpool TENNIS 9 p.m. TENNIS — United Cup: Spain v. Kazakhstan 4 a.m. (Friday) TENNIS — United Cup: China v. Brazil 6 a.m. (Friday) TENNIS — United Cup: China v. Brazil The Associated Press created this story using technology provided by Data Skrive TV listings provided by LiveSportsOnTV .State semifinals await for Ryan and ArgyleThe year in money: inflation eased, optimism ticked upward
Dem Rep. Gottheimer: Feds Not Giving Public Enough Information on Drones
Dallas Cowboys star guard Zack Martin is doubtful for Sunday's game against the Washington Commanders due to ankle and shoulder injuries. Martin didn't practice at all this week. He also physically struggled during Monday night's loss to the Houston Texas. Martin, who turned 34 on Wednesday, has started all 162 games played in 11 seasons with the Cowboys. He's a nine-time Pro Bowl selection and a seven-time first-team All-Pro. Tight end Jake Ferguson (concussion) and safety Markquese Bell (shoulder) have been ruled out. Neither player practiced this week after being hurt against the Texans. Cornerback DaRon Bland (foot) practiced in full this week and will make his season debut. He was injured in August. Star wideout CeeDee Lamb (back/foot) was a full practice participant on Friday and is good to go. Cornerback Trevon Diggs (groin/knee) and receiver Brandin Cooks (knee) are among six players listed as questionable. The others are offensive tackle Chuma Edoga (toe), guard Tyler Smith (ankle/knee), defensive end Marshawn Kneeland (knee) and linebacker Nick Vigil (foot). This article first appeared on Field Level Media and was syndicated with permission.World Chess Championship: Gukesh enters unchartered territory riding high on good form but don't write off Liren
UN digital program seeks to empower Africa's public workers
(BPT) - This article was sponsored and developed by Neurocrine Biosciences, Inc. Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. 1-2 It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. 3 CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. 4 Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. 5-6 According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. 7 Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website here . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. 8 However, it is common for both chorea and dystonia movements to be present together. 6 For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. 9 Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. 10-12 "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." Treatment Options There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. 3 Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Ongoing Research Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the KINECT ® -DCP clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: FindADCPStudy.com . REFERENCES © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024
'Malcolm in the Middle' to offer new episodes with Frankie Muniz, Bryan Cranston and Jane Kaczmarek Frankie Muniz, Bryan Cranston and Jane Kaczmarek are reuniting for a new four-episode run of “Malcolm in the Middle” for Disney+ — 25 years after the beloved sitcom first launched. The show ran for seven seasons starting in 2000 and was hailed for looking at ordinary life through the eyes of an extraordinary youngster, now fully grown: Malcolm, played by Muniz, has a genius I.Q. The new four episodes will be crafted by original series creator Linwood Boomer. No air dates were announced. “Malcolm in the Middle” originally aired on Fox and ended its run in 2006. Woman who falsely accused Duke lacrosse players of rape in 2006 publicly admits she lied RALEIGH, N.C. (AP) — The woman who in 2006 falsely accused three Duke University lacrosse players of raping her has admitted publicly for the first time that she made up the story. The accusations made national headlines at the time, stirring tensions about race, class and the privilege of college athletes. Crystal Mangum, who is Black, said in an interview with the “Let’s Talk with Kat” podcast that she “made up a story that wasn’t true” about the white players who attended a party where she was hired to perform as a stripper “because I wanted validation from people and not from God.” The former Duke players were declared innocent in 2007 after Mangum’s story fell apart under legal scrutiny. Sophia, a famous robot and global icon of AI, wins hearts at Zimbabwe's innovation fair HARARE, Zimbabwe (AP) — Sophia, a world-renowned robot, has been the center of attention at an Artificial Intelligence and Innovation fair in Zimbabwe this week. Described as an AI global icon by the U.N., Sophia can hold human-like conversations with people and recognize their gestures. As a special guest at the week-long event at the University of Zimbabwe, she answered questions on academic topics from researchers. Children quizzed her about the bible, God and her birth. She also made clear her aversion to human food and romance. The United Nations Development Program said it brought Sophia to Zimbabwe as part of efforts to “inspire youth, policymakers, and innovators to embrace AI as a catalyst for development.” Stanley recalls millions of travel mugs over concerns the lids might fall off, causing burns Stanley is recalling approximately 2.6 million of its switchback and trigger action stainless steel travel mugs sold in the U.S. because of a potential burn hazard. The company said that the mug’s lid threads can shrink when exposed to heat and torque, causing the lid to detach during use, posing a burn hazard. Stanley has received 91 reports worldwide, including 16 in the U.S., of the recalled travel mugs’ lids detaching during use, resulting in 38 burn injuries worldwide, including two burn injuries in the U.S., with 11 consumers worldwide requiring medical attention. Miami Dolphins release veteran receiver Odell Beckham Jr. MIAMI GARDENS, Fla. (AP) — The Miami Dolphins released wide receiver Odell Beckham Jr. on Friday, ending the former Pro Bowler’s short tenure with the team. Beckham had missed the past two days of practice for what the team called personal reasons. Dolphins coach Mike McDaniel indicated that the decision to part ways was mutual. Beckham signed a one-year deal with the Dolphins in May, but started the season on the physically unable to perform list after offseason knee surgery. Since his Dolphins debut in Week 5 against New England, Beckham had just nine catches for 55 yards in nine games. Bird strike disables a jetliner engine and forces an emergency landing at JFK airport NEW YORK (AP) — Authorities say a bird strike involving an American Airlines jetliner disabled one of the plane’s two engines shortly after takeoff from New York’s LaGuardia Airport. The plane was forced to turn around and land at John F. Kennedy International Airport. Airline officials say no one was injured. Flight 1722 took off from LaGuardia at 7:43 p.m. Thursday with a destination of Charlotte, North Carolina. Airport officials say it safely made an emergency landing at Kennedy at 8:03 p.m. The Federal Aviation Administration is investigating. The agency received reports of 19,400 strikes at 713 airports across the U.S. last year alone. Rarely do they force jetliners to make emergency landings. 49ers LB De'Vondre Campbell refuses to enter game after losing his starting spot SANTA CLARA, Calif. (AP) — San Francisco linebacker De’Vondre Campbell refused to enter the game in the third quarter after losing his starting job when Dre Greenlaw returned from an injury. Campbell played 90% of defensive snaps for the 49ers but was benched after Greenlaw came back for his first game since tearing his left Achilles tendon in last season’s Super Bowl. When Greenlaw left with soreness in the third quarter Thursday night against the Rams, Campbell told the coaches he didn't want to play and left the field. Coach Kyle Shanahan says he has never seen that before and the team will “figure out something” on how to deal with it going forward. 'Crown of Thorns' returns to Notre Dame Cathedral for public veneration PARIS (AP) — An ancient relic that many Christians revere as Jesus Christ’s “Crown of Thorns” has returned to Notre Dame, five years after it was saved from the flames of the cathedral’s devastating 2019 fire. The crown — a circular band of branches encased in a gilded golden tube — was brought back to its historic home Friday in a ceremony. The event was presided over by the archbishop of Paris and attended by knights and dames of the Equestrian Order of the Holy Sepulcher, marking a key moment in the cathedral’s restoration journey. In 1239, it was acquired by King Louis IX of France, who brought it to Paris. 'Vanderpump Rules' star James Kennedy arrested on suspicion of misdemeanor domestic violence BURBANK, Calif. (AP) — Police say “Vanderpump Rules” star James Kennedy has been arrested on suspicion of misdemeanor domestic violence. Police in Burbank, California, say officers investigated reports of an argument between a man and a woman at a residence late Tuesday night and arrested the 32-year-old Kennedy. He was released from jail after posting bail. A representative of Kennedy did not immediately respond to a message seeking comment. The Burbank city attorney will decide whether to file charges. Kennedy is a DJ and reality TV star who has appeared for 10 seasons on “Vanderpump Rules” — the Bravo series about the lives of employees at a set of swank restaurants. Dick Vitale says he's cancer-free after 4th bout with the disease in just over 3 years Dick Vitale said he’s cancer-free after his fourth bout with the disease in just over three years. The 85-year-old ESPN college basketball analyst posted Thursday on X that he got the news after a morning scan, saying: “SANTA CLAUS came early as Dr Rick Brown called & said that my PET SCAN at 7 AM came back CLEAN OF CANCER !” Vitale posted on X. “OMG thanks so much to ALL of YOU for your (prayers). Yes I’m cutting the nets down baby it’s my National Championship!” Vitale had surgery in the summer to remove cancerous lymph nodes from his neck. The Basketball Hall of Famer was previously treated for melanoma and lymphoma, and had radiation treatments last year for vocal cord cancer.
has unveiled the latest addition to its G-Lide collection of watches. Made for extreme sports under the Japanese company’s branding, the GLX-5600KB is the third model created in collaboration with pro Kanoa Igarashi. The 27-year-old Huntington Beach, California, native has been at or near the top of the surf world for nearly a decade. In 2017, Igarashi won the WSL Vans U.S. Open of Surfing. Two years later he became the first Asian to claim victory at the Corona Bali Protected, the third event of the Men’s Championship Tour. At the Tokyo 2020 Olympic Games, he represented Japan and brought home the silver medal. And most recently, at the 2022 ISA World Surfing Games, Igarashi captured his first long-sought World Champion title. Javascript is required for you to be able to read premium content. Thanks for the feedback.Eliza Wilson is a little nervous as she draws the microphone close, but she is determined to share her life story. “My father was a disabled veteran,” she says. “I first experienced homelessness when I was 5 years old.” Wilson, who’s 36, leads programs focused on unhoused youth. On a recent Saturday, she is addressing a citizen assembly, a grassroots gathering seeking solutions to tough local challenges. Her audience consists of 30 ordinary Oregonians . They are acupuncturists and elk hunters; house cleaners and retired riverboat pilots. None are public policy experts. All the same, these participants have been asked to recommend new strategies for combating youth homelessness — a major problem in this affluent Oregon city and the surrounding rural areas of Deschutes County. This unusual experiment in small-D democracy is underwritten by more than $250,000 in grants from backers such as the Rockefeller Foundation and Omidyar Network. As a key early presenter, Wilson wins rapt attention, clicking through data-rich slides and sharing her story of crisis and recovery. That’s how citizen assemblies should work, says Kevin O’Neil, an innovation specialist at the Rockefeller Foundation. His research shows Americans are frustrated with what they perceive as aloofness and gridlock within civic institutions. “ People want to be directly involved in decision-making,” O’Neil says. “They recognize the value of expertise, but they don’t want to delegate decision-making to experts.” Assemblies can help “overcome polarization and strengthen societal cohesion,” says Claudia Chwalisz, founder of DemocracyNext. Her nonprofit, launched in Paris in 2022, champions such assemblies worldwide, hoping they can “create the democratic spaces for everyday people to grapple with the complexity of policy issues, listen to one another, and find common ground.” At least, that’s the theory. To succeed, citizen assemblies can’t settle for a few days of harmonious dialogue among well-intentioned strangers. They need to inspire policy changes or new programs from government and other civic institutions. In Europe, such wins abound. In the United States, results are spottier. The most fruitful U.S. effort to date was a 2021 people’s assembly in Washington State that produced 148 ideas — including more solar canopies and food composting — to combat climate change. More often, progress is challenging. An assembly in 2022 in Petaluma, California, spun up ideas to repurpose a long-time county fairground site. Two years later, the fair still operates under short-term leases; its long-term destiny remains in limbo. In Colorado’s Montrose County, enacting an assembly’s bold ideas for improving rural day care has been “more of a marathon than a sprint,” says organizer Morgan Lasher. Can central Oregon do better? It may take years to know, but evidence so far shows both the assembly system’s opportunities and the challenges. Bend’s local economy is strong, with a jobless rate of just 4.2% and median household income of more than $80,000. As housing costs have skyrocketed, though, the spectacle of people living in tent and trailer encampments has become more common. A January count found more than 1,800 people were homeless in Deschutes County, up from 913 in 2020. In 2023, DemocracyNext and Healthy Democracy, a Portland, Oregon, nonprofit, connected with Bend officials interested in bringing the assembly idea to central Oregon. Josh Burgess, an Air Force veteran, who moved to Bend and became the proverbial “advance man” for DemocracyNext. Operating in a county evenly divided between Democrats and Republicans, Burgess built rapport with both liberal and conservative members on the Deschutes County Board of Commissioners. “It took four or five meetings to get there,” Burgess recalls. Organizers decided to focus on homelessness among ages 14 to 24, where opportunities for progress seemed greatest. To pick citizens for the assembly, organizers contacted 12,000 county residents before selecting just 30. Everything was balanced by age, race, gender, and geography – a slow, costly requirement. Even so, advocates such as Michelle Barsa of Omidyar Network says assemblies’ big edge comes from using “an actual representative sample of the community, not just the people who always show up at town-hall meetings and yell into a microphone for three minutes.” At the northern edge of Oregon State’s Bend campus, a few hundred yards from the Deschutes River, is the McGrath Family atrium, a sunlight-drenched space with panoramic woodland views. It feels almost like a spa. As the Bend assembly gets started, black tablecloths at a huge, U-shaped table convey gravity. Name tags identify attendees as “Noelle,” “Dave,” “Alex.” The first few hours go slowly, but everything perks up after lunch. Eliza Wilson takes command, introducing herself as director of runaway and homeless youth services at J Bar J, a social-services organization. Her voice is unfailingly steady, but emotions race fast across her face: hope, frustration, empathy, resolve, and more. “Teens get really good at hiding their homelessness,” Wilson explains. “We don’t share family business outside of the family. I was really fortunate that a high-school counselor pointed me, at age 15, to the first youth shelter that had just opened in Bend. I stayed there for three years, until I graduated from high school. I finally got on my feet at age 21.” As Wilson finishes, questions stream in. “Are there any programs advocating for children to get back to their parents?” one woman wants to know. “Is there open communication between you guys and the school district?” a man asks. Wilson and other presenters respond with a road map of what exists today. They point out how homeless youth are in a precarious but not hopeless situation, counting on allies for a couch to sleep on. Less than 20 percent live outside in encampments. Practically everyone in the audience takes notes. The next day, assembly members strike up conversations with young adults who were once homeless. Chronic problems — and glimmers of ideas about how to address them — tumble forth. Flaws in the foster parent system. The risk of sexual abuse. The unique challenges that LGBTQ youth face. Attendees — who shared their thoughts with the Chronicle on the condition they be identified only by their first name — regarded those conversations as eye-opening breakthroughs in their hunt for policy recommendations. “I’m coming away with a whole different point of view,” Ken told me. He had arrived believing that poor parenting and drug abuse led to homelessness, and that affected families should personally address such challenges. Now, he said, he was interested in broader solutions. Several local officials stopped by to watch the assembly proceedings. Phil Chang, a Deschutes County commissioner, said the broad-based assembly creates “social license for us to do things that the community wants.” Conservative county commissioner Tony DeBone worries that Oregon’s rollback of drug-offense laws has worsened social problems; he also believes that an economic upturn would do the most good. Still, he says, he’s willing to see what the assembly can offer. Ultimately, the assembly’s effectiveness will depend on whether its recommendations can overcome bureaucratic inertia, says Tammy Baney, executive director of the Central Oregon Intergovernmental Council. Proposed changes in police interactions with homeless youth could be acted on within a month or two if local law enforcement is receptive, she says. Improving Oregon’s gridlocked foster-care system might be much harder. “It all depends on how much political will there is,” Baney says. _____ George Anders is editor-at-large at the Chronicle of Philanthropy, where you can read the full article. This article was provided to The Associated Press by the Chronicle of Philanthropy as part of a partnership to cover philanthropy and nonprofits supported by the Lilly Endowment. The Chronicle is solely responsible for the content. For all of AP’s philanthropy coverage, visit https://apnews.com/hub/philanthropy.
Newcastle woman wins big on BBC Michael McIntyre's The Wheel
