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BERWYN, Pa.--(BUSINESS WIRE)--Nov 21, 2024-- Virpax Pharmaceuticals, Inc. (Nasdaq: VRPX) (“Virpax” or the “Company”) , a company specializing in developing pharmaceutical products for pain management, announced that it has been granted an extension of its cooperative research and development agreement with the National Center for Advancing Translational Sciences (NCATS), an institute/center of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. This collaboration is for the continued development of Virpax’s product candidate, NES100, an intranasal peptide, for the management of acute and chronic non-cancer pain. NES100 is an enkephalin drug product based on a type of nanotechnology delivery approach. Enkephalin is a naturally occurring (endogenous) peptide that is not easily administered in its original form. We believe that the nanotechnology may enable and enhance the delivery of this metabolically labile peptide drug into the brain. NES100 is the first investigational product formulation delivered via the nasal route with the potential to enhance enkephalin transport to the brain. NES100 uses a preassembled device and cartridge to propel the enkephalin formulation through the nose to the brain by flowing along the olfactory nerve pathway. The Molecular Envelope Technology (MET) is designed to protect and help carry the drug to the brain with the goal of promptly suppressing pain by binding to the delta opioid receptors. NES100 has demonstrated analgesic potential in animal models without the development of opioid tolerance, withdrawal, respiratory depression, euphoria, or addiction associated with use of opioids. Jatinder Dhaliwal, Chief Executive Officer of Virpax, commented, "We are excited that this collaboration has been extended with NCATS and the NIH Helping to End Addiction Long-term (HEAL) initiative as we believe that it may help Virpax develop an effective and safe alternative to conventional opioids used by patients to manage acute and chronic pain. We believe that the NIH/NCATS collaborative agreement will enable our team to maintain momentum in both our pre-clinical and clinical development strategies." About Virpax Pharmaceuticals Virpax is developing branded, non-addictive pain management products candidates using its proprietary technologies to optimize and target drug delivery. Virpax is initially seeking FDA approval for two prescription drug candidates that employ two different patented drug delivery platforms. ProbudurTM is a single injection liposomal bupivacaine formulation being developed to manage post-operative pain and EnveltaTM is an intranasal molecular envelope enkephalin formulation being developed to manage acute and chronic pain, including pain associated with cancer. Virpax is also using its intranasal Molecular Envelope Technology (MET) to develop one other prescription product candidate, NobrXiolTM, which is being developed for the nasal delivery of a pharmaceutical-grade cannabidiol (CBD) for the management of rare pediatric epilepsy. Virpax has competitive cooperative research and development agreements (CRADAs) for two of its prescription drug candidates, one with the National Institutes of Health (NIH) and one with the Department of Defense (DOD). Virpax is also seeking partners for two nonprescription product candidates: AnQlar, which is being developed to inhibit viral replication caused by influenza or SARS-CoV-2, and EpoladermTM, which is a topical diclofenac spray film formulation being developed to manage pain associated with osteoarthritis. For more information, please visit https://www.virpaxpharma.com .and follow us on Twitter, LinkedIn and YouTube. Forward-Looking Statements This press release contains certain forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995, as amended, including those described below. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions. These statements may be identified by the use of forward-looking expressions, including, but not limited to, “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “potential,” “predict,” “project,” “should,” “would” and similar expressions and the negatives of those terms. These statements relate to future events and involve known and unknown risks, uncertainties, and other factors, including the additional capital which will be necessary to complete studies and clinical trials that the Company plans to initiate and other factors listed under “Risk Factors” in the Company’s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q that the Company has filed with the U.S. Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise. View source version on businesswire.com : https://www.businesswire.com/news/home/20241121242163/en/ CONTACT: Investor Contact: info@virpaxpharma.com KEYWORD: PENNSYLVANIA UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: BIOTECHNOLOGY MEDICAL DEVICES HEALTH PHARMACEUTICAL MEDICAL SUPPLIES SOURCE: Virpax Pharmaceuticals, Inc. Copyright Business Wire 2024. PUB: 11/21/2024 04:05 PM/DISC: 11/21/2024 04:06 PM http://www.businesswire.com/news/home/20241121242163/en
Watch: Is Jerod Mayo holding the Patriots back?In what is being called a ‘gross failure’ of security, a stowaway was able to evade multiple security checkpoints to board a flight from New York to Paris, where she was caught after disrupting the flight. A on CNN says a woman identified as Svetlana Dali completed security screening and bypassed two identity verification and boarding status stations without a boarding pass – which the Transportation Security Administration (TSA) confirms. Although TSA has not shared further details on how Dali skirted , reports say she got through without showing a boarding pass, passport – or, presumably, any other form of ID – meaning fake ID or fraudulent documents were likely not involved. The BBC’s take on the story says she “managed to dodge” document and ID checks. Dali has a U.S. green card and a Russian passport, but does not qualify for entry into Europe. She is now being held in the ZAPI waiting zone at Charles de Gaulle airport, awaiting deportation back to the States. Six major airports in Thailand are expanding facial recognition options to passengers on international flights. The will be available to international travelers at airports in Chiang Mai, Chiang Rai, Don Mueang, Hat Yai, Phuket and Suvarnabhumi. Estimates say the face biometrics system will reduce boarding time per passenger from three minutes to one. It also applies to baggage drop, enabling travelers to check bags without the need for a passport or ID document. Thailand’s airport authority says stored biometric data will be erased 48 hours after registration. The biometric passenger processing system at Thailand airports was deployed by local integrator and includes kiosks and gates . It can also authenticate airport staff. The Canadian Press that Air Canada will install facial recognition gates for boarding in Vancouver, in an effort to make the process more efficient. The opt-in program will allow passengers to walk onto a plane without showing a passport or piece of physical ID. Canada’s largest airline launched a in 2023 for digital ID in its frequent traveler Maple Leaf lounges in Toronto, Calgary and San Francisco. It plans to expand its biometrics program to boarding gates at more airports soon. New biometrics deployments in Sao Paulo, Paris, Vancouver and Thailand show airports continuing their global shift toward biometrics for check-in, security and other uses. Aeroin that Brazil’s National Civil Aviation Agency (ANAC) has approved an addendum to the concession contract for Guarulhos International Airport, opening the door for new investments in facial recognition technology to be used in passenger and and immigration control. The investment of R$450 million (roughly US$74.2 million), which aims to increase security and efficiency in passenger identification and baggage processes, will be shared between and other security measures such as x-rays and explosives detectors. A featuring representatives from Idemia and Air France delves into the programme at Paris Airport to offer AI-powered luggage identification via the ALIX tool. is expanding use cases for ALIX across the airport journey, and focusing particularly on biometric bag check and return tools. Idemia notes that a key to success in a complex bag handling system is training operators to work with AI systems, so that they are seen as helping, rather than as replacements for human labor. They also note that the airport has been keen to deploy across the facility: “the airport is not an obstacle.” | | | | | | | | |