Five-Year Results Confirm Genentech’s Polivy Combination Therapy as New Standard of Care for Previously Untreated Aggressive LymphomaOTTAWA — Foreign Affairs Minister Mélanie Joly welcomed president-elect Donald Trump's pick for the next U.S. ambassador in Ottawa, a former longtime Michigan congressional representative who voted for NAFTA and later wavered on new free trade deals. Joly said at a news conference on Thursday at the Canadian Embassy in Washington, D.C., that she takes it as a good sign that Trump endorsed the Canada-U.S.-Mexico free-trade deal when he announced Pete Hoekstra as his next envoy to Canada. She also posted on social media Thursday that Canada looks forward to working with Hoekstra to strengthen bilateral ties and advance shared priorities "as close allies and neighbours." The minister was in Washington to talk trade and security with U.S. senators from both parties. Her meeting schedule included top Republican senators Lindsey Graham, Rick Scott and Lisa Murkowski. Following this trip, Joly is headed to the Halifax International Security Forum, where she said she will be meeting with more U.S. lawmakers, including Sen. James Risch from Idaho. Hoekstra will still have to be confirmed by the U.S. Senate, but his early nomination is being taken as a good sign by several former diplomats. Former Canadian diplomat Colin Robertson, who has met with Hoekstra before, said he's someone Canada can work with. "He's not from the (WWE) or Fox News. He's an ambassador in the Netherlands previously ... and he's from Michigan, so somebody who understands Canada," Robertson said. "He's well suited to the posting and I think it'll be easier to do business with somebody who has his depth of experience." Canada's ambassador in Washington, Kirsten Hillman, also congratulated Hoekstra on the nomination, posting on social media she looks forward to working with him to make the bilateral relationship "even stronger." Hoekstra was a nine-term border-state lawmaker and holds high esteem in Trump's world. His long career in politics left a wake of stunning headlines, including for a 2012 Super Bowl ad critics and even some Republicans slammed as blatantly racist. He was Trump's chosen chairman for the Michigan GOP during a power struggle between two pro-Trump camps. He spoke at Trump rallies in the swing state during the campaign and earned high praise from the president-elect. "This guy, Hoekstra — he's unbelievable," Trump said at a February rally in Waterford Township, Mich. "Everything he did in Congress, he was incredible, and then he was an unbelievable ambassador." In his first term as president, Trump tapped Hoekstra to serve as U.S. ambassador to the Netherlands, where he was at one point embroiled in a political interference scandal for hosting a fundraiser at the U.S. Embassy with members of the far-right party Forum for Democracy. In a 2019 public talk organized by a Dutch news magazine, he said it's "not an unrealistic ask" that every member of NATO meets the target of spending the equivalent of two per cent of GDP on defence by 2024 — something Trump has railed about, and something Canada will not do until at least 2032. At an event in Ottawa last month, Trump's former ambassador to Canada Kelly Craft said his administration would expect Canada to meet that target much sooner than 2032. Hoekstra was a representative for Michigan from 1993 until 2011 and chaired the powerful House Intelligence Committee. In 2019, Trump floated him as a possible pick for national intelligence director. Not long after he was first elected, he voted in favour of the NAFTA trade deal in 1993 — something he called at the time a simple choice yet also the "toughest decision I have had to face in my first 11 months in office," according to Michigan newspaper reports from the time. By 2003, he was opposed to inking free-trade deals, including two proposed with Singapore and Chile, saying that NAFTA led to manufacturers in Michigan to "shift production to Canada and Mexico." Nearly a decade later, in 2011, he singled out NAFTA as something that had "come to symbolize what Americans believe is unfair trade." In the early 2000s, he was one of a number of Michigan lawmakers from both parties raising ire over Toronto shipping its trash into his state. "Michigan is better than taking Canadian trash," he was quoted saying in 2004 in the local Michigan newspaper the Ludington Daily News. The next year he co-signed a letter advocating for a bill that would clamp down on "foreign municipal solid waste" entering his state, according to an Associated Press report from the time. This report by The Canadian Press was first published Nov. 21, 2024. Kyle Duggan, The Canadian Press
NASHVILLE, Tenn. (AP) — Tennessee Titans coach Brian Callahan said Wednesday that wide receiver Treylon Burks , who's been on injured reserve since mid-October with an injured knee, recently had surgery to fix a partially torn ACL. “It was a loose ACL that wasn’t fully torn, and so they had to go see a specialist, so some weeks went by after he went on IR and he eventually had to have ACL surgery,” Callahan said. “The surgery was a couple of weeks back, and the time from when he went to IR until he had the surgery was also a couple of weeks.” Burks was hurt in practice the week after the Titans lost to Indianapolis on Oct. 13 and placed on injured reserve on Oct. 19. The 2022 first-round pick is no stranger to injuries. He suffered concussions in both 2022 against Philadelphia and last year against Pittsburgh. Burks missed six games in each of his first two seasons with the Titans and played in just five games this season before being placed on injured reserve. He finished 2024 with four receptions for 34 yards. For his three NFL seasons, Burks has 53 receptions for 699 yards and one touchdown catch. The Titans (3-9) host Jacksonville (2-10) on Sunday. Window opened The Titans opened the three-week practice window for offensive tackle Jaelyn Duncan to return from injured reserve. Duncan has started two games, the second against Buffalo on Oct. 20 at right tackle and lasted four snaps before hurting his hamstring. He was placed on injured reserve Oct. 26. ___ AP NFL: https://apnews.com/hub/nfl Terry Mccormick, The Associated PressAncient discovery answers big Bible questionThe new, 12-team College Football Playoff brings with it a promise to be bigger, more exciting, more lucrative. Perfect or 100% fair? Well, nobody ever believed that. The first expanded playoff bracket unveiled Sunday left a presumably deserving Alabama team on the sideline in favor of an SMU squad that finished with a better record after playing a schedule that was not as difficult. It ranked undefeated Oregon first but set up a possible rematch against Ohio State, the team that came closest to beating the Ducks this year. It treated underdog Boise State like a favorite and banged-up Georgia like a world beater at No. 2. It gave Ohio State home-field advantage against Tennessee for reasons it would take a supercomputer to figure out. It gave the sport the multiweek tournament it has longed for, but also ensured there will be plenty to grouse about between now and when the trophy is handed out on Jan. 20 after what will easily be the longest college football season in history. All of it, thankfully, will be sorted out on the field starting with first-round games on campuses Dec. 20 and 21, then over three succeeding rounds that will wind their way through traditional bowl sites. Maybe Oregon coach Dan Lanning, whose undefeated Ducks are the favorite to win it all, put it best when he offered: "Winning a national championship is not supposed to be easy.” Neither, it turns out, is figuring out who should play for it. The Big Ten will lead the way with four teams in the tournament, followed by the SEC with three and the ACC with two. The lasting memory from the inaugural bracket will involve the decision that handed the ACC that second bid. Alabama of the SEC didn't play Saturday. SMU of the ACC did. The Mustangs fell behind by three touchdowns to Clemson before coming back to tie. But they ultimately lost 34-31 on a 56-yard field goal as time expired. “We were on pins and needles,” SMU coach Rhett Lashley said. “Until we saw the name ‘SMU’ up there, we were hanging on the edge. We're really, really happy and thankful to the committee for rewarding our guys for their total body of work." The Mustangs only had two losses, compared to three for the Crimson Tide. Even though SMU's schedule wasn't nearly as tough, the committee was impressed by the way the Mustangs came back against Clemson. “We just felt, in this particular case, SMU had the nod above Alabama,” said Michigan athletic director Warde Manuel, the chairman of the selection committee. “But it’s no disrespect to Alabama’s strength of schedule. We looked at the entire body of work for both teams.” Alabama athletic director Greg Byrne was gracious, up to a point. “Disappointed with the outcome and felt we were one of the 12 best teams in the country,” he said on social media. He acknowledged — despite all of Alabama’s losses coming against conference opponents this season — that the Tide’s push to schedule more games against teams from other major conferences in order to improve its strength of schedule did not pay off this time. “That is not good for college football," Byrne said. Georgia, the SEC champion, was seeded second; Boise State, the Mountain West champion, earned the third seed; and Big 12 titlist Arizona State got the fourth seed and the fourth and final first-round bye. All will play in quarterfinals at bowl games on Dec. 31-Jan. 1. Clemson stole a bid and the 12th seed with its crazy win over SMU, the result that ultimately cost Alabama a spot in the field. The Tigers moved to No. 16 in the rankings, but got in as the fifth-best conference winner. The conference commissioners' idea to give conference champions preferable treatment in this first iteration of the 12-team playoff could be up for reconsideration after this season. The committee actually ranked Boise State, the Mountain West Champion, at No. 9 and Big 12 champion Arizona State at No. 12, but both get to skip the first round. Another CFP guideline: There’s no reseeding of teams after each round, which means no break for Oregon. The top-seeded Ducks will face the winner of Tennessee-Ohio State in the Rose Bowl. Oregon beat Ohio State 32-31 earlier this year in one of the season’s best games. No. 12 Clemson at No. 5 Texas, Dec. 21. Clemson is riding high after the SMU upset, while Texas is 0-2 against Georgia and 11-0 vs. everyone else this season. The winner faces ... Arizona State in the Peach Bowl. Huh? No. 11 SMU at No. 6 Penn State, Dec. 21. The biggest knock against the Mustangs was that they didn't play any big boys with that 60th-ranked strength of schedule. Well, now they get to. The winner faces ... Boise State in the Fiesta Bowl. Yes, SMU vs. Boise was the quarterfinal we all expected. No. 10 Indiana at No. 7 Notre Dame, Dec. 20. Hoosiers coach Curt Cignetti thought his team deserved a home game. Well, not quite but close. The winner faces ... Georgia in the Sugar Bowl. The Bulldogs got the No. 2 seed despite a throwing-arm injury to QB Carson Beck. But what else was the committee supposed to do? No. 9 Tennessee at No. 8 Ohio State , Dec. 21. The Buckeyes (losses to Oregon, Michigan) got home field over the Volunteers (losses to Arkansas, Georgia) in a matchup of programs with two of the biggest stadiums in football. The winner faces ... Oregon in the Rose Bowl. Feels like that matchup should come in the semifinals or later. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football
What a merger between Nissan and Honda means for the automakers and the industryPurple Heart medal’s owner identified as ‘a man’s man’ who fought in WWII
Ryan Day spoke to the media after the game about Caleb Downs’ performance and that last touchdown drive. Javascript is required for you to be able to read premium content. Thanks for the feedback.IBC speeded up recovery of Rs 10.22 lakh crore from defaulting firms: GovtEU Ambassador Highlights PharmaVax Ghana’s Role in Transforming Africa’s Vaccine Production
GTA 6 fans disappointed as 'moon theory' for trailer release debunked
Gophers look to duplicate 2019 upset of Penn State on SaturdayPolice, prosecutors disagree on Criminal Code release ‘mandate’
ATLANTA (AP) — Jimmy Carter, the peanut farmer who tried to restore virtue to the White House after the Watergate scandal and Vietnam War, then rebounded from a landslide defeat to become a global advocate of human rights and democracy, has died. He was 100 years old . The Carter Center said the 39th president died Sunday, more than a year after entering hospice care , at his home in Plains, Georgia, where he and his wife, Rosalynn, who died in November 2023, lived most of their lives. A moderate Democrat, Carter ran for president in 1976 as a little-known Georgia governor with a broad grin, effusive Baptist faith and technocratic plans for efficient government. His promise to never deceive the American people resonated after Richard Nixon’s disgrace and U.S. defeat in southeast Asia. “If I ever lie to you, if I ever make a misleading statement, don’t vote for me. I would not deserve to be your president,” Carter said. Carter’s victory over Republican Gerald Ford, whose fortunes fell after pardoning Nixon, came amid Cold War pressures, turbulent oil markets and social upheaval over race, women’s rights and America’s role in the world. His achievements included brokering Mideast peace by keeping Egyptian President Anwar Sadat and Israeli Prime Minister Menachem Begin at Camp David for 13 days in 1978. But his coalition splintered under double-digit inflation and the 444-day hostage crisis in Iran. His negotiations ultimately brought all the hostages home alive, but in a final insult, Iran didn’t release them until the inauguration of Ronald Reagan, who had trounced him in the 1980 election. Humbled and back home in Georgia, Carter said his faith demanded that he keep doing whatever he could, for as long as he could, to try to make a difference. He and Rosalynn co-founded The Carter Center in 1982 and spent the next 40 years traveling the world as peacemakers, human rights advocates and champions of democracy and public health. Awarded the Nobel Peace Prize in 2002, Carter helped ease nuclear tensions in North and South Korea, avert a U.S. invasion of Haiti and negotiate cease-fires in Bosnia and Sudan. By 2022, the center had monitored at least 113 elections around the world. Carter was determined to eradicate guinea worm infections as one of many health initiatives. Swinging hammers into their 90s, the Carters built homes with Habitat for Humanity. The common observation that he was better as an ex-president rankled Carter. His allies were pleased that he lived long enough to see biographers and historians revisit his presidency and declare it more impactful than many understood at the time. Propelled in 1976 by voters in Iowa and then across the South, Carter ran a no-frills campaign. Americans were captivated by the earnest engineer, and while an election-year Playboy interview drew snickers when he said he “had looked on many women with lust. I’ve committed adultery in my heart many times,” voters tired of political cynicism found it endearing. The first family set an informal tone in the White House, carrying their own luggage, trying to silence the Marine Band’s traditional “Hail to the Chief" and enrolling daughter, Amy, in public schools. Carter was lampooned for wearing a cardigan and urging Americans to turn down their thermostats. But Carter set the stage for an economic revival and sharply reduced America's dependence on foreign oil by deregulating the energy industry along with airlines, trains and trucking. He established the departments of Energy and Education, appointed record numbers of women and nonwhites to federal posts, preserved millions of acres of Alaskan wilderness and pardoned most Vietnam draft evaders. Emphasizing human rights , he ended most support for military dictators and took on bribery by multinational corporations by signing the Foreign Corrupt Practices Act. He persuaded the Senate to ratify the Panama Canal treaties and normalized relations with China, an outgrowth of Nixon’s outreach to Beijing. But crippling turns in foreign affairs took their toll. When OPEC hiked crude prices, making drivers line up for gasoline as inflation spiked to 11%, Carter tried to encourage Americans to overcome “a crisis of confidence.” Many voters lost confidence in Carter instead after the infamous address that media dubbed his “malaise" speech, even though he never used that word. After Carter reluctantly agreed to admit the exiled Shah of Iran to the U.S. for medical treatment, the American Embassy in Tehran was overrun in 1979. Negotiations to quickly free the hostages broke down, and then eight Americans died when a top-secret military rescue attempt failed. Carter also had to reverse course on the SALT II nuclear arms treaty after the Soviets invaded Afghanistan in 1979. Though historians would later credit Carter's diplomatic efforts for hastening the end of the Cold war, Republicans labeled his soft power weak. Reagan’s “make America great again” appeals resonated, and he beat Carter in all but six states. Born Oct. 1, 1924, James Earl Carter Jr. married fellow Plains native Rosalynn Smith in 1946, the year he graduated from the Naval Academy. He brought his young family back to Plains after his father died, abandoning his Navy career, and they soon turned their ambitions to politics . Carter reached the state Senate in 1962. After rural white and Black voters elected him governor in 1970, he drew national attention by declaring that “the time for racial discrimination is over.” Carter published more than 30 books and remained influential as his center turned its democracy advocacy onto U.S. politics, monitoring an audit of Georgia’s 2020 presidential election results. After a 2015 cancer diagnosis, Carter said he felt “perfectly at ease with whatever comes.” “I’ve had a wonderful life,” he said. “I’ve had thousands of friends, I’ve had an exciting, adventurous and gratifying existence.” Contributors include former AP staffer Alex Sanz in Atlanta.See how Oyedepo's Winners Chapel is planning to protect childrenBetMGM College Football Odds: Boise State by 22 1/2. Series record: Boise State leads 17-1. Boise State enters its final conference game of the season with an eight-game winning streak - its longest single-season winning streak since 2014 - and with its sights set on a potential top-four seed in the College Football Playoff. With Boise State in front of BYU, the Broncos became the provisional No. 4 seed in the playoff with two weeks left in the regular season. Despite being mired in a two-win season, Wyoming would love to play the spoiler role against the Broncos. Wyoming’s rushing defense against Heisman Trophy candidate Ashton Jeanty. The junior running back comes into this one leading the nation in several categories, including rushing yards (1,893), rushing touchdowns (26), total touchdowns (27) and all-purpose yards (1,991). The Cowboys rank 116th in the nation in allowing 201.2 yards rushing per game. Boise State: WR Cameron Camper continues to play a pivotal role for the Broncos. As Jeanty draws the attention of opposing defensive units, it creates space in the secondary for Camper to operate. The senior leads the Broncos with 665 yards receiving with 40 catches, including four touchdowns. Wyoming: DE DeVonne Harris has proven to be effective for the Cowboys since missing time earlier this season with an injury. Harris registered a season-high six tackles with a tackle for loss and a fumble recovery at Colorado State and has three tackles for loss this season. Harris could be tasked to slow Jeanty in the running lanes while also applying pressure to Boise State quarterback Maddux Madsen. Boise State and Wyoming are two of the best teams on third downs on both sides of the ball with the Broncos’ offense checking in third nationally in third-down conversion percentage (52.7%) and Wyoming’s defense ranked fifth in the country in third-down conversion percentage against (.285). ... The Broncos, who own the third-best rushing offense in the country with 258.7 yards rushing per game, have run for 200 or more yards in eight games this season. ... Wyoming linebacker Connor Shay ranks second on the team with 62 tackles this season. His 6.2 tackles per game rank 20th in the conference. .. Wyoming has won 65.9% of its games in War Memorial Stadium, though the Cowboys are just 1-4 in Laramie this season. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here. AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football .