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The Trump Trade rally has stocks at record highs. Where do we go from here?Seated in the stands, Athiya Shetty was visibly disheartened by her husband’s dismissal. The drama unfolded at the iconic Melbourne Cricket Ground (MCG) during the final day of the fourth Test in the Border-Gavaskar Trophy 2024-25. With India chasing a mammoth target of 340 runs, Australian skipper Pat Cummins turned the tide in favor of the hosts, delivering a double blow that sent shockwaves through Indian fans. Among the most talked-about moments was KL Rahul’s dismissal for a five-ball duck and the viral reaction of his wife, Bollywood actress Athiya Shetty. A post shared by cricket.com.au (@cricketcomau) Anushka Sharma & Athiya Shetty's reaction after KL Rahul got out for Duck _ by skipper Pat Cummins. #INDvsAUS #INDvAUS pic.twitter.com/apmp7yt1mt — The Great Khan __ (@GreatChinggis) December 30, 2024 Anushka Sharma and Athiya Shetty's reaction on KL Rahul's Wicket. [Hotstar] #AUSvIND pic.twitter.com/t58FydFImU — Digital Hunt 247 (@digitalhunt247) December 30, 2024 Also Read: India vs Australia Day 5 4th Test Live Streaming: When And Where To Watch Boxing Day Test Live In India On TV & Online? Pat Cummins Sets the Stage with a Stellar Over India’s chase began under immense pressure, and the early dismissals of Rohit Sharma and KL Rahul in the same over added to the tension. Cummins, showcasing his mastery with the ball, delivered a scrambled seam delivery that caught Rahul off-guard. The extra bounce did the trick as Rahul edged the ball to Usman Khawaja in the slips, leaving India at 2/21. Rahul’s wicket was particularly significant as the batter had been moved to No. 3 after opening in the first three Tests. While his prior performances in the series included a couple of half-centuries, the transition down the order did not yield the desired results. Athiya Shetty's Viral Moment Seated in the stands, Athiya Shetty was visibly disheartened by her husband’s dismissal. Cameras captured her heartbreaking reaction as she clasped her hands in dismay, a poignant reminder of the emotional toll cricket takes on players’ families. The video quickly made rounds on social media, with fans expressing empathy for both Athiya and KL Rahul. The clip resonated with cricket enthusiasts, sparking debates about the pressures faced by players on the international stage and the unwavering support of their loved ones. India’s Struggles Continue India’s batting woes didn’t end with Rahul’s departure. Just before lunch, Virat Kohli was caught in the slips off a Mitchell Starc delivery, leaving the visitors reeling at 3/33. Kohli, one of India’s most dependable batters against Australia, managed just five runs off 29 balls. Despite a promising partnership between Rohit Sharma and Yashasvi Jaiswal earlier in the innings, the Indian lineup faltered against the relentless Australian pace attack. Cummins, who had already dismissed Rahul in the first innings for 24, once again proved why he is among the world’s most feared bowlers. Pat Cummins: The Architect of Australia’s Dominance Cummins’ all-round contributions were pivotal in Australia’s commanding position. After scoring crucial runs lower down the order in both innings—49 and 41—he followed up with a brilliant display of bowling. His ability to extract bounce and movement on a fifth-day pitch at the MCG highlighted his class and leadership. Cummins’ performance was complemented by Mitchell Starc, who consistently troubled India’s top-order batters. Together, the Australian pace duo ensured that India faced an uphill battle in their pursuit of a historic win. Social Media Reacts Athiya Shetty’s reaction wasn’t the only viral moment of the day. Cricket fans flooded social media with posts praising Pat Cummins’ brilliance and lamenting India’s collapse. Memes, heartfelt messages, and debates about India’s batting order dominated platforms like Twitter and Instagram. Athiya’s candid moment served as a reminder of the personal sacrifices and emotional investments involved in professional sports. It also shed light on the often-overlooked human aspect of the game, resonating with fans across the globe. A Test Match to Remember While India’s chances of pulling off a miraculous chase appeared slim by lunch, the fourth Test will be remembered for its intense drama and standout performances. Pat Cummins emerged as the hero of the match, leaving an indelible mark with both bat and ball. As the Border-Gavaskar Trophy inches towards its conclusion, moments like Athiya Shetty’s reaction and Cummins’ game-changing over encapsulate the beauty and unpredictability of Test cricket. Stay informed on all the latest news , real-time breaking news updates, and follow all the important headlines in india news and world News on Zee News.Châtillon, France, December 11 th , 2024 DBV Confirms Alignment with U.S. FDA on Accelerated Approval Pathway for the Viaskin® Peanut Patch in Toddlers 1 - 3 Years-Old "DBV is pleased to have received, what we believe to be, a clear and reasonable pathway towards an Accelerated Approval for the Viaskin Peanut patch in toddlers 1 - 3-years-old. This comes on the heels of our October 22 nd press release announcing details in support of our separate Viaskin Peanut programs in 4 - 7 year-olds and in 1 - 7 year-olds in Europe,” said Daniel Tassé, Chief Executive Officer, DBV Technologies. "We believe we have decreased the regulatory pathway risk of our programs. DBV can now fully focus on executing the remaining studies that will support two distinct BLAs across age groups and an MAA in Europe. We are grateful to the Agency for its attentive collaboration as we continue to work towards introducing this novel therapy to caregivers and patients as expeditiously as possible.” Accelerated Approval Pathway The FDA recently issued written communication confirming an Accelerated Approval pathway for the Viaskin Peanut patch in toddlers 1 - 3-years-old. As a reminder, current FDA guidance for Accelerated Approval includes three qualifying criteria: FDA and DBV have been engaged in ongoing dialogue throughout Q4 of this year regarding the intermediate clinical endpoint necessary to meet the third criterion. In the recent written communication, the FDA confirmed the efficacy data from the Company's Phase 3 EPITOPE study can serve as an intermediate clinical endpoint. The FDA has agreed that the endpoint is reasonably likely to predict clinical benefit and will therefore fulfill the requirement for Accelerated Approval. In preparation for commercialization, DBV made slight modifications to the Viaskin Peanut patch used in EPITOPE to increase the simplicity of application for the caregiver and provide product identification on each patch. No changes, including patch shape or size, were made to the device components that are in contact with the patient's skin. Further, to increase the volume of patch production for future commercialization, changes needed to be made to the manufacturing process and location. Although the intended commercial Viaskin Peanut patch is currently being used (N=304) in the ongoing 3-year Open Label Extension to EPITOPE, the collective changes to the commercial Viaskin Peanut patch were viewed by the FDA as constituting a different product relative to the clinical patch used in the EPITOPE study. The Company intends to use the commercial Viaskin Peanut patch in both the COMFORT Toddlers study and the post-marketing confirmatory study. Post-Marketing Confirmatory Study In the recent written communication, FDA confirmed criteria for a post-marketing confirmatory study in toddlers 1 - 3-years-old. DBV and FDA agreed that the confirmatory study will assess the effectiveness of the intended commercial Viaskin Peanut patch and will need to be initiated at the time that the BLA is submitted. To date, the commercial patch has been used in 304 subjects with over 234,695 patient-days of therapy in the placebo crossover and the EPITOPE Open Label Extension, with no clinically relevant differences in efficacy or safety vs. the clinical patch used in the EPITOPE Phase 3 trial. The confirmatory study will include a double-blind, placebo-controlled food challenge (DBPCFC) and will use the same statistical criteria for success (i.e., lower bound of the 95% CI > 15%) as used in the EPITOPE Phase 3 efficacy study. Adhesion data for the post-marketing confirmatory study will be collected in a similar manner relative to the COMFORT Toddlers study. The Company expects these data will further support the importance of average daily wear time in the use of the Viaskin Peanut patch as it relates to efficacy and labeling. "When it comes to food allergy management, what works for one family, might not work for another. That is why having varied treatment options available is so incredibly important to our community,” said Sung Poblete, PhD, RN, CEO of FARE (Food Allergy Research & Education). "I'm pleased to learn that DBV's constructive dialogue with the FDA has resulted in this Accelerated Approval guidance outlining remaining developmental steps for the Viaskin Peanut patch in toddlers with a peanut allergy. At FARE, we look forward to the possibility that one day, if approved, caregivers and families will have this exciting new treatment as an option to consider.” COMFORT Toddlers Supplemental Safety Study COMFORT Toddlers is a Phase 3 double-blind, placebo-controlled (DBPC) study designed to generate additional safety (primary endpoint) and adhesion data of the Viaskin Peanut patch in peanut allergic toddlers 1 - 3-years old. DBV is pleased to announce that Dr. Julie Wang, MD, Professor of Pediatrics, Jaffe Food Allergy Institute, the Icahn school of Medicine at Mount Sinai, will act as the Global Principal Investigator for the COMFORT Toddlers study. "I am thrilled to assume the role of Global Principal Investigator of the COMFORT Toddlers study,” stated Dr. Julie Wang, Professor of Pediatrics, Jaffe Food Allergy Institute, Icahn school of Medicine at Mount Sinai in New York. "Viaskin Peanut, if approved, would offer a much-needed alternative treatment option for patients and caregivers. I look forward to working with the DBV team to advance this important clinical trial.” The Company anticipates that COMFORT Toddlers will enroll approximately 480 subjects randomized 3:1 (active: placebo) at approximately 80 - 90 study centers across the U.S., Canada, Australia, and Europe. COMFORT Toddlers will be a six-month study followed by an optional 18-month open-label treatment phase, to provide 24 or 18 months of treatment with the Viaskin Peanut patch for participants randomized to the active or placebo groups, respectively. Thus, the COMFORT Toddlers study will increase the total subjects exposed to the Viaskin Peanut patch for at least six-months in a controlled study to 600, as required by FDA. In total, there will be approximately 240 subjects with the clinical patch in EPITOPE and 360 with the commercial patch in COMFORT Toddlers. As previously disclosed , DBV and FDA have aligned on a patch wear time collection methodology, analysis and study objective hierarchy in the COMFORT Toddlers study. The agreed-upon adhesion data collection methodology provides a practical approach for subjects, families, and investigators. The methodology is intended to generate sufficient data to support a BLA submission under the Accelerated Approval pathway (i.e., collecting patch adhesion data with a focus on daily wear time at relevant time points). We believe there are three positive outcomes coming out of the productive discussions with FDA: Biologic License Application Submission in 1 - 3 Year-Olds There will be two Phase 3 studies in 1 - 3-year-olds using the Viaskin Peanut patch. The data generated from the studies will be used to inform a BLA submission: Investor Conference Call and Webcast DBV management will host an investor conference call and webcast today, Wednesday, December 11 th , at 5:00pm EST, to discuss these regulatory updates. This call is accessible via the below teleconferencing numbers and requesting the DBV Technologies call. About DBV Technologies DBV Technologies is a clinical-stage biopharmaceutical company developing treatment options for food allergies and other immunologic conditions with significant unmet medical need. DBV is currently focused on investigating the use of its proprietary Viaskin® patch technology to address food allergies, which are caused by a hypersensitive immune reaction and characterized by a range of symptoms varying in severity from mild to life-threatening anaphylaxis. Millions of people live with food allergies, including young children. Through epicutaneous immunotherapy (EPITTM), the Viaskin® patch is designed to introduce microgram amounts of a biologically active compound to the immune system through intact skin. EPIT is a new class of non-invasive treatment that seeks to modify an individual's underlying allergy by re-educating the immune system to become desensitized to allergen by leveraging the skin's immune tolerizing properties. DBV is committed to transforming the care of food allergic people. The Company's food allergy programs include ongoing clinical trials of Viaskin Peanut in peanut allergic toddlers (1 through 3 years of age) and children (4 through 7 years of age). DBV Technologies is headquartered in Châtillon, France, with North American operations in Warren, NJ. The Company's ordinary shares are traded on segment B of Euronext Paris (Ticker: DBV, ISIN code: FR0010417345) and the Company's ADSs (each representing five ordinary shares) are traded on the Nasdaq Capital Market (Ticker: DBVT; CUSIP: 23306J309). For more information, please visit www.dbv-technologies.com and engage with us on X (formerly Twitter) and LinkedIn . Forward Looking Statements This press release may contain forward-looking statements and estimates, including statements regarding the therapeutic potential of Viaskin® Peanut patch and EPITTM, designs of DBV's anticipated clinical trials, DBV's planned regulatory and clinical efforts including timing and results of communications with regulatory agencies, plans and expectations regarding initiation of the confirmatory study, plans and expectations with respect to COMFORT Toddlers and COMFORT Children, plans and expectations with respect to the submission of BLAs to FDA, anticipated support for the BLA submission, DBV's expectations with respect to the Accelerated Approval pathway and any other actionable regulatory pathway, and the ability of any of DBV's product candidates, if approved, to improve the lives of patients with food allergies. These forward-looking statements and estimates are not promises or guarantees and involve substantial risks and uncertainties. At this stage, DBV's product candidates have not been authorized for sale in any country. Among the factors that could cause actual results to differ materially from those described or projected herein include uncertainties associated generally with research and development, clinical trials and related regulatory reviews and approvals, and DBV's ability to successfully execute on its budget discipline measures. A further list and description of risks and uncertainties that could cause actual results to differ materially from those set forth in the forward-looking statements in this press release can be found in DBV's regulatory filings with the French Autorité des Marchés Financiers ("AMF”), DBV's filings and reports with the U.S. Securities and Exchange Commission ("SEC”), including in DBV's Annual Report on Form 10-K for the year ended December 31, 2023, filed with the SEC on March 7, 2024, and future filings and reports made with the AMF and SEC by DBV. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements and estimates, which speak only as of the date hereof. Other than as required by applicable law, DBV Technologies undertakes no obligation to update or revise the information contained in this Press Release. Viaskin is a registered trademark and EPIT is a trademark of DBV Technologies. Investor Contact Katie Matthews DBV Technologies [email protected] Media Contact Angela Marcucci DBV Technologies [email protected] Attachment PDF VersionFormer US President Jimmy Carter dies at age 100
No matter how much a financial system is fortified against scams, there is always a fraudster, a conman, or a swindler aiming to game that system. Financial crimes, a la white-collar crimes, are committed, interestingly, by those working closely with the system or those having the innate skill to justify the art through the framework of ‘fraud triangle’, that is in the terms of opportunity, incentive and rationalization. Scams, mainly the pecuniary ones, involve conduct of dishonest practices leading to perversion, depravity and debasement of the entire morals of the social fabric. Financial scandals, like any other scandal, have a story of their own and, of course, the denouement. The truth of the scandals appears to be a drama at times, and at times an enthralling thriller. Vijay Narayan Govind, in his book , promises to tell select 10 true stories of financial scams, spread across centuries and continents, and in his own words, “these frauds were significant enough at the time to send major ripples through the systems they challenged, with many of them serving as the catalyst for key legal and regulatory reforms.” The book introduces 10 swindlers, each with their own story of fraud in a separate chapter with a suitable story-title to it. In Govind’s fraudster tales, Hegestratos’s tale emerges as the ‘First Fraudster’, circa 300 BCE, in Athens. He, along with his crime partner Zenosthemis, working as ship merchants, planned to steal the cargos, sink the vessel, and con the vessel’s insurers of shipload of valuable goods through enforcement of the clauses of bottomry and respondentia contracts. However, the plans went awry due to the alert captain and crew members and Hegestra tos jumped and drowned himself in the sea. Zenos themis was arrested, tried and imprisoned in Athens for a long time. The author picks stories, random perhaps, from Athens and other countries, including India. Haridas Mundhra in the tale of ‘The Great Investor’ and Natwarlal in ‘The Master Manipulator’ are the two Indians figuring in the book. The Mundhra scandal, first of its kind in independent India, not only was embroiled with the stock markets and financial institutions but was an expose of the wicked nexus between political party, bureaucracy, ministers and business class, perhaps a prototype of ‘crony capitalism’. The conman Mudhra duped Life Insurance Company (LIC) by forging share certificates, using them as collateral for loans, and amassing huge loans to the tune of Rs 15.60 crore by the mid of 1957. It was Feroz Gandhi, the law maker, who brought this scam to public attention that led to nationalisation of LIC, resignation of TT Krishnamachari – then finance minister, indictment of finance secretary and some senior LIC officials, and, of course, sentencing of Haridas Mundhra to 22 years in prison. In the Mithilesh Kumar alias Natwarlal’s case, the story, though intriguing, is simple. From forging signatures and withdrawing money from banks, he graduated to nefarious crimes such as decamping cash from merchants and siphoning off goods from the cargo areas while using more than 50 aliases. Natwarlal even sold, impersonating himself as government official, the Taj Mahal thrice, the Red Fort twice, and the Rashtrapati Bhawan and Parliament once. He had developed this shrewd art of escaping prison, and one heard him saying quite often that ‘no jail is enough to hold me for too long’. Then, there is a story of how an expert William Chaloner counterfeited coins, notes, and lottery tickets, in the 1600s, but finally got caught by Sir Issac Newton, and sent to gallows for he was guilty of multiple currency frauds. Hugh Cameron’s story is about his conspiracy to cheat Royal British Banks and its customers, eventually which led to the Bank’s collapse. However, in due course, it triggered major legislative reforms in the corporate governance systems in Britain. Oscar Hartzell, a brazen rook, in another story, swindled millions of dollars from investors in a popularly known Sir Francis Drake estate scam. Another story, rather smutty and historical, called the ‘necklace scandal’, involves one French noble woman Jeanne de valois as the key conspirator. It became one of the scandals that led to French Revolution. US major Enron bankruptcy, led by Kenneth Lay, and the Ponzi scheme by Charles Ponzi, the two white-collar financial crimes, rocked the financial systems in the US. The 10 tales are fun, and a riveting read and, in the tales, the readers would find themselves in the murky world of scandals. The criminals of the stories have two things in common, one they dreamt of becoming filthy rich in a trice, and when caught they tried to justify that all is done in good faith, and second, all of them are caught and punished, which the author seems to lay down as the moral of the book.City of Edmonton planning to sell 2 downtown office buildings, relocate hundreds of staff
CEAT Kelani Holdings has broadened the scope of its flagship community initiative promoting road safety around schools by engaging with the Police and the Sri Lanka Corps of Military Police (SLCMP) of the Sri Lanka Army, two institutions that play lead roles in this domain. The company recently presented stocks of traffic management-related signboards and traffic cones to these institutions, as one of its community commitments that makes up the ‘CEAT Cares’ portfolio of community projects. The signboards and traffic cones presented to the Cinnamon Gardens Police Station are to be strategically placed on main roads to facilitate traffic management near schools, government institutions, and other high-traffic areas within the station’s jurisdiction, supporting CEAT’s efforts to help improve road safety and aid law enforcement maintain smooth traffic flows. Meanwhile, the signboards presented to the Military Police of the Sri Lanka Army will facilitate the SLCMP’s role in traffic control and ensuring safety during major national celebrations such as the Independence Day celebrations and national war heroes commemoration ceremonies, as well as events organised by the Sri Lanka Army. An articulation of CEAT’s credo – “Making mobility safer and smarter every day” – the CEAT Cares programme has been sustained by CEAT Kelani Holdings since 2010 and has benefitted 290 schools across the country to date. It involves the presentation of traffic safety equipment to schools located close to main roads and in high congestion zones as part of the company’s continuing commitment to make commuting safer, especially for school children. This flagship community initiative was designed to reflect CEAT’s focus on safety on the roads – a key element in all its products. The largest domestic manufacturer of cross-ply and radial tyres in Sri Lanka, CEAT Kelani Holdings currently manufactures half of the country’s pneumatic tyre requirements, and exports about 20 per cent of its production to 16 countries. The joint venture’s cumulative investment in Sri Lanka over the past decade alone exceeds Rs 8.5 billion.Pickleball's popularity soared in 2024 and it reached the masses in the year. Pickleball is the fastest-growing sport in the US and its popularity is on the rise across the globe. Tennis players love to play pickleball and many of them have become pro-pickleball players. Pickleball is a hugely popular sport. Here, we have a look at 3 sporting personalities who tried their hand at pickleball in 2024 - Novak Djokovic Novak Djokovic was the most famous sporting personality who played pickleball in 2024. A month before trying the sport, the tennis legend had warned the tennis clubs against its increasing popularity. The 24-time Grand Slam champion was joined by Jannik Sinner, Barbora Krejcikova and Callie Smith in a friendly pickleball game. He could play the sport again during the Australian Open 2025. Suryakumar Yadav India cricketer Suryakumar Yadav tried his hand at pickleball with Prithvi Shaw and other members of the Mumbai cricket team during the Syed Mushtaq Ali Trophy. The Mumbai teammates played the sport at the Pickleball arena in Secunderabad. Apart from Suryakumar, Sanju Samson, Ruturaj Gaikwad and Sai Sudharsan have also played pickleball. Its popularity is on the rise in India too. Becky Lynch WWE superstar Becky Lynch tried pickleball during her break from the in-ring action. She shared a pic on social media to reveal that she played pickleball. The former women's champion has been out of action since May. Becky's contract with WWE ended in May and she has been away from the company since then. While there is no update about her return date, she is confirmed to make her return ahead of Wrestlemania 41. Becky lost to Rhea Ripley in the opening match of Wrestlemania 40. Her husband, Seth Rollins made his WWE return in June. He will face CM Punk on Raw's Netflix debut. Get Latest News Live on Times Now along with Breaking News and Top Headlines from Pickleball, Sports and around the world.On December 30th, BTS’ Kim Taehyung, aka V, turns 29, and it’s the perfect time to look back at some of his most iconic and precious moments with Jungkook and Jimin. Known for his infectious charisma, V’s playful, goofy, and heartwarming interactions with his fellow members have left ARMY swooning time and time again. From his cheeky pranks with Jimin to sweet gestures with Jungkook, every moment captures the essence of V’s fun-loving spirit. His bond with both the 'maknae' Jungkook and his soulmate Jimin is truly something special. So, in celebration of his big day, here are 7 of the most adorable, unforgettable, and precious moments between V and his BTS brothers that show just how much they mean to each other! BTS V aka Kim Taehyung’s Birthday: From HBD Wishes on Burj Khalifa to Sand Art in Odisha, Here’s How ARMY Across the World Is Celebrating K-Pop Singer’s Special Day! . In one iconic episode of BTS’s variety show Run BTS, V and Jungkook had a jelly bean challenge, where they had to guess the flavour. V’s reactions were priceless, especially when Jungkook’s cheeky smile made V burst into laughter. During an interview, V gave Jungkook a rare, sweet compliment. He described him as the ‘best vocalist’. Jungkook was visibly moved, and fans couldn’t stop swooning over this heartwarming exchange. During one BTS In the Soop episode, V and Jimin were shown relaxing in their little cabin. Jimin tried to wake V up from his nap, but V was so out of it, that he hilariously responded with nonsensical words that left Jimin giggling. During BTS’s birthday celebrations, Jimin lovingly fed V a slice of cake, and the adorable moment was filled with laughter and affection. V even cheekily said, “This is too sweet for me,” but he couldn’t get enough of Jimin’s thoughtful gesture. BTS V aka Kim Taehyung Birthday: From Inner Child To Winter Bear, 5 Solo Songs of the K-Pop Singer You Got to Listen to If You Aren't Part of the BTS Army! . Jungkook’s mischievous ways sometimes get him into trouble, but V’s protective nature always comes through. On multiple occasions, when Jungkook was getting teased or making a mess, V would step in to ‘save’ him, often getting overly dramatic in the process. At the end of a live stream, V, Jungkook, and Jimin held hands and made a perfect heart-shaped gesture towards the camera, sending ARMY into a frenzy. V excitedly shouted, "It's my birthday!" as a way to share his special moment with the fans. The crowd erupted in cheers, completely immersed in his infectious energy and celebration. V's playful announcement made the moment even more memorable for both him and ARMY. That time Taehyung went “it’s my birthday!” during a Fire performance pic.twitter.com/4xcRlbwaYH — Still With You 7 ☔️ (@stillwithyou875) December 30, 2023 V, born on December 30, 1995, is set to celebrate his birthday this year. Since the start of 2024, he has had an incredible year, marked by numerous solo releases and continued success. As V celebrates his 29th, let’s raise a toast to these heartwarming moments that remind us just how strong and sweet the bonds of BTS truly are! (The above story first appeared on LatestLY on Dec 30, 2024 08:20 AM IST. For more news and updates on politics, world, sports, entertainment and lifestyle, log on to our website latestly.com ).Georgia AG Chris Carr launches GOP campaign for governor, kicking off 2026 race
N.H. swing dancing recovers from the pandemic; can it survive tech isolation?