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5 ways to tell if you’re on track for retirement — and 5 things to do if you need to catch up, according to expertsBill Clinton, the former US president who has faced a series of health issues over the years, was admitted to hospital Monday in Washington after developing a fever, his office said. "President Clinton was admitted to Georgetown University Medical Center this afternoon for testing and observation after developing a fever," the 78-year-old's deputy chief of staff Angel Urena said on social media platform X, adding Clinton "remains in good spirits." Clinton was previously hospitalized for five nights in October 2021 due to a blood infection. In 2004, at age 58, he underwent a quadruple bypass operation after doctors found signs of extensive heart disease. He had stents implanted in his coronary artery six years later. The health scare motivated him to make lifestyle changes, including adopting a vegetarian diet, and he has since spoken publicly about his efforts. Clinton's health last made headlines in November 2022 when he tested positive for Covid-19. He said at the time that his symptoms were "mild" and he was "grateful to be vaccinated and boosted." Clinton, who led the United States for two presidential terms from 1993-2001, is the second-youngest living US president, after 63-year-old Barack Obama. He was born mere months after fellow former US president George W. Bush and President-elect Donald Trump. Though his prosperous time in office was marred by scandals, he has enjoyed a second life in the two decades after his presidency, which has seen him venture into numerous diplomatic and humanitarian causes. bur-jgc/ahaAmbitious Digital Nation Pakistan Act to be tabled in NA on 16th

Class is in session once again, but you’d better hide this report card from your parents. In the vastness of college football’s 2024 season, Oklahoma State is one of the flunking students. But how bad really is it? It’s pretty bad – with a few slivers of promise. The most polarizing position on the football field certainly wasn’t good, but it wasn’t the root cause of OSU’s struggles. Through three games, Alan Bowman was ranked sixth nationally in passing yards heading into conference play. That’s when things went downhill. It began with his benching in the second half against Utah. From there, Bowman lost the job to Garrett Rangel at BYU and to Maealiuaki Smith for the last two games. In total, Oklahoma State’s three quarterbacks threw 17 interceptions – which ranked 130th nationally. Bowman threw an interception in nine straight games down the stretch of the season. Glimpses of quality QB play from Rangel against BYU and Smith against Texas Tech gave OSU its best chances to win a conference game, but the other shortcomings were too overwhelming. The most experienced unit in college football didn’t pull its weight in 2024. The inability to control the line of scrimmage was a major weakness for a unit that did it so well the season prior – which also led to a massive disparity in time of possession. The two worst possession-time differentials in OSU history happened this season against Utah and West Virginia. The most telling metric is the Cowboys’ six games that they averaged 3.5 yards per carry or less, and the team overall finishing with 800 less total rushing yards than last season. In a season of darkness, Brennan Presley and Co. were a beacon of light. Presley made Cowboy football history against TCU when he hauled in his 293rd career reception to pass Rashaun Woods for most receptions in OSU history. In that same game, he became the fourth player in program history to eclipse 5,000 all-purpose yards. In his five seasons in Stillwater, Presley has cemented himself among the most beloved to wear the uniform. He’s a guy that should be a lock for the Cowboy Hall of Fame and should be in consideration to have his No. 80 in the Ring of Honor down the road at some point. This grade applies to both offense and defense. It’s a bold decision to dial up back-to-back Alan Bowman QB draws in plus territory against Kansas State. It’s equally bold to sit back and let BYU steal a game from you in the closing seconds with no two-deep safety and a refusal to ever use a QB spy against mobile quarterbacks. Mike Gundy said himself at different points this season that he wasn’t impressed by the offensive or defensive gameplan after a game. Would it have made a difference in the season if this was better? Who knows, but we saw glimpses of a great offensive game plan against BYU and Texas Tech. Here’s where things get really bad. Not only was this one of the worst defenses in the country this season, it was the worst in Oklahoma State football history. By a lot. Brian Nardo’s defense surrendered 285 pass yards per game this season – which, for comparison, is 50 yards per game worse than 2021’s Kansas Jayhawks that finished 2-10. His defense also ranked 132nd out of 133 teams in explosive plays (gains of 20-plus yards) allowed this season. As bad as the rushing offense was, the run defense was worse. The Pokes were 129th nationally in yards allowed on the ground and it’s arguable that it looked even worse than that number suggests. From the Big 12 opener against Utah through the Arizona State game, OSU allowed 225 or more rushing yards in six straight games. Third-down defense: F- The last grade is the worst one, and it was OSU’s biggest detriment this season. During the nine-game losing streak through conference play, the Cowboy defense could not get its awful defense off the field. The Pokes allowed teams to convert 47% on third downs and even when they could get a rare stop, they allowed 16 of 30 fourth down conversions. Over the final four games of the season, the defense allowed 35 of 50 third down conversions and five of seven fourth downs. Ryan Breeden is a sports reporter for The Stillwater News Press. He can be contacted at rbreeden@stwnewspress.com .Conor McGregor must pay $250K to woman who says he raped her, civil jury rulesFootball: Coach Prime’s CU Buffs set to add young talent as signing period begins

December 13, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked peer-reviewed publication trusted source proofread by Delft University of Technology Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they have now discovered that these motors also put significant twists into the loops that they form. These findings help us better understand the structure and function of our chromosomes. They also provide insight into how disruption of twisted DNA looping can affect health—for instance, in developmental diseases like "cohesinopathies." The scientists published their findings in Science Advances . Imagine trying to fit two meters of rope into a space much smaller than the tip of a needle—that's the challenge every cell in your body faces when packing its DNA into its tiny nucleus. To achieve this, nature employs ingenious strategies, like twisting the DNA into coils of coils, so-called "supercoils" and wrapping it around special proteins for compact storage. Small DNA loops regulate chromosome functions However, compaction isn't enough. Cells also need to regulate the chromosome structure to enable its function. For example, when genetic information needs to be accessed, the DNA is locally read off. In particular, when it's time for a cell to divide, the DNA must first unpack, duplicate, and then properly separate into two new cells. Specialized protein machines called SMC complexes (structural maintenance of chromosomes) play a critical role in these processes. Just a few years ago, scientists at Delft and other places discovered that these SMC proteins are molecular motors that make long loops in our DNA, and that these loops are the key regulators of chromosome function. In the lab of Cees Dekker at TU Delft, postdocs Richard Janissen and Roman Bath now provide clues that help to crack this puzzle. They developed a new way to use "magnetic tweezers" by which they could watch individual SMC proteins make looping steps in DNA. Importantly, they were also able to resolve if the SMC protein would change the twist in the DNA. And strikingly, the team found that it did: the human SMC protein cohesin does indeed not only pull DNA into a loop, but also twists the DNA in a left-handed way by 0.6 turns in each step of creating the loop. A glimpse into the evolution of SMC proteins What's more, the team found that this twisting action isn't unique to humans. Similar SMC proteins in yeast behave the same way. Remarkably, all the various types of SMC proteins from humans and yeast add the same amount of twist—they turn DNA 0.6 times at every DNA loop extrusion step. This shows that the DNA extrusion and twisting mechanisms stayed the same for very long times during evolution. No matter whether DNA is looped in humans, yeast, or any other cell—nature employs the same strategy. These new findings will provide essential clues for resolving the molecular mechanism of this new type of motor. Additionally, they make clear that DNA looping also affects the supercoiling state of our chromosomes, which directly affects processes like gene expression. Finally, these SMC proteins are related to various diseases such as Cornelia de Lange Syndrome, and a better understanding of these processes is vital for tracking down the molecular origins of these serious illnesses. More information: Richard Janissen et al, All eukaryotic SMC proteins induce a twist of -0.6 at each DNA-loop-extrusion step, Science Advances (2024). DOI: 10.1126/sciadv.adt1832 . www.science.org/doi/10.1126/sciadv.adt1832 Journal information: Science Advances Provided by Delft University of Technology

After 23 years on air, ESPN’s Around the Horn will reportedly stop production in 2025 . Longtime host Tony Reali addressed the latest episode with his usual professionalism, opting not to note the impending cancellation rumors and delivering the show’s signature monologue on sports topics of the day instead. Dressed in all black, Reali confidently opened the latest Thursday episode with discussions about the Ravens- Steelers rivalry, Colorado’s recruitment of 5-star quarterback prospect Julian Lewis to replace Shedeur Sanders and the ever-shifting landscape of college football due to NIL . The 46-year-old host did not mention the NY Post’s Wednesday report confirming the show’s end, keeping the positive and inviting tone that has made him a fan favorite. Reali’s decision to avoid addressing the elephant in the room was a masterclass in professionalism in the eyes of his online supporters. Instead of focusing on the potential end of an era, he delivered the sports content that the show's viewers have come to expect with his panel of re-appearing journalists, including Dallas Morning News columnist Tim Cowlishaw, Andscape journalist David Dennis Jr, NFL analyst Kevin Clark, and ESPN's Pardon the Interruption guest host Bob Ryan. The debate and game show, mostly known for its buzzer sounds, unpredictable point-scoring system, and witty exchanges with the top national sports journalists, has been a staple of ESPN’s programming. Despite the NY Post’s report , ESPN has yet to confirm the decision publicly. Reports suggest that the network's higher-ups pushed for the show’s end as part of their broader efforts to revamp traditional programming. Fans tried to solve the mystery themselves, going on social media to ask him personally and seek answers. Reali’s Twitter and Instagram accounts have been flooded with comments asking for confirmation or a farewell statement. Instead, Reali has shared glimpses of his personal life, including reading with his son Enzo and continuing to promote the show. "Shame. Only watch ESPN for ATH and PTI," one fan wrote on Reddit , which was supported by 49 others on the thread. Another fan of the show wrote, "I hope someone at ESPN monitors comments about their shows. A lot of us won’t be watching anything but live events, if they go through with this." Since its debut in 2002, Around the Horn has helped create and feature some of ESPN's biggest stars, including Sportscenter host Elle Duncan, NFL star journalist Mina Kimes , NBA analyst Monica McNutt, Woody Paige, Ramona Shelburne, and Pablo Torre. It introduced a new format where sports journalists in opposing major markets debated the hottest topics, earning points for strong arguments and deductions for weak takes. READ MORE Reali took over the hosting job in 2004 from boxing journalist Max Kellerman, who began the show but then left to join Fox Sports. Before accepting the role, the Staten Island native covered the New York Yankees, Giants, Jets, and Mets for a local NY TV station affiliated with the TV network The CW.

You have questions. I have some answers. Q: I heard there will be another season of “Gentleman Jack.” Is this true, or has the series been canceled? A: The series based on the life of Anne Lister, a lesbian landowner in England in the 1830s, ran for two seasons and 16 total episodes on HBO, which co-produced the series with the BBC. Reviews were overwhelmingly positive. Still, HBO dropped out of production before a third season could be made. The BBC reportedly sought a new producing partner for the third season, but so far without success. You can find the two seasons on Max. And, if you’re wondering what the title meant, it was an insulting nickname from Lister’s neighbors: “gentleman” referring to Lister’s masculine look and “jack” to her love for women. Q: In 1964 (approximately) there was a half-hour show called “Hank” about a young man attempting to gain knowledge from college classes but who was not registered at the school. It didn’t run for long. Can I find it anywhere? A: “Hank” originally aired for 26 episodes on NBC in 1965-66. Dick Kallman — an award-winning stage actor and singer — played the title character. As you remembered, Hank was an orphaned young man dropping into college classes — and running various businesses to support himself and his sister (Katie Sweet). While the series was not a hit, it has enough admirers for a DVD release of the series, which is for sale on Amazon. There’s also “Dick Kallman Drops in as Hank,” an album of Kallman singing, on music streaming services including Spotify. And you TV loving readers may also remember “Hank,” a Kelsey Grammer comedy with a different premise than the ‘60s show, which had a short run in 2009. Q: I’ve been a lover of trains since I was a little boy. I remember watching a 30-minute show called “Casey Jones” about the famous locomotive engineer. I believe Alan Hale Sr. starred in the title role. Do you have any information about the availability of some or all of the episodes? A: “Casey Jones” originally aired in 1957-58 (and my memory of it as a kid suggests it was rerun for a lot longer). Alan Hale Jr. – later famous as the Skipper on “Gilligan’s Island” starred. Alan Hale Sr., his father, was a renowned character actor who passed away in 1950. As for “Casey Jones,” you can find episodes on YouTube. Q: While I usually watch a lot of PBS or history channels, I have started watching “Murder in a Small Town” on Fox. Please tell me it will be back! A: The drama based on books by L.R. Wright ended its first season after eight episodes in November. I’ve not seen an official announcement of a second season, but various published interviews have included the producers’ plans for another run, and work on new scripts. Q: I’ve been unsuccessful in trying to find the movie “The Tango Lesson.” When I search my streaming services from time to time, the response I get is that it is currently unavailable. Even looking for a DVD copy is frustrating. There are copies of dubious quality, and it’s not clear they are playable in North America. Any suggestions? A: Written and directed by Sally Potter (who also starred), “The Tango Lesson” is a 1997 drama about a filmmaker who becomes fascinated with the tango — and a dancer. Reviews were mixed — it’s at 50% on Rotten Tomatoes — but it can be found on digital. Fandango at Home has it for rent for $3.99 and for sale for $13.99; Apple TV has it for the same rental price and a $12.99 purchase.A version of this story originally ran Sept. 30, 2024. When Stacy Fox heard the news that Freehold Raceway — known as the oldest racing track in the country — was shutting down this December, she was crestfallen. “I literally cried because my whole childhood was at the track,” said Fox, 46, who now lives in Savannah, Georgia, but grew up in Browns Mills in Pemberton Township in Burlington County. Both of her parents worked at the Monmouth County track — her father was a head accountant there for more than 30 years, and her mother worked the simulcasting switchboard at night. Fox remembers driving to the raceway with her mother before her shift, and riding back home with her father, at the end of his work day. She often spent Sundays at the track, when her father would catch up on work. She knew dozens of people who worked at the raceway. Even decades later, she has vivid memories of the thrill of spending time there with her brother, the family’s two youngest siblings. They peeked into the track’s vault filled with money, walked through the cigar smoke-filled club, met the jockeys and stroked the horses. “My dad was a big part of that place,” Fox said of her father, who died in 2000. After she learned the raceway was closing, she visited the track one final time in October with her mother, when they traveled to New Jersey. Coincidentally, her parents’ anniversary falls on the track’s last day — Dec. 28. In September, officials announced the horse-racing track, which features harness racing, is ceasing all live racing and simulcasting operations at the end of the year. New Jersey’s other tracks — Monmouth Park and the Meadowlands — are not affected by the closure. “This was an extremely difficult decision, especially given the historical importance of Freehold Raceway to the local community and the New Jersey horse racing industry,” Howard Bruno, the raceway’s general manager, said in the announcement. “Unfortunately, the operations of the racetrack cannot continue under existing conditions, and we do not see a plausible way forward,” he said. “We are incredibly thankful for our dedicated employees, horsemen and fan base for their support and patronage for so many years.” News of the closure prompted a flood of reactions and hundreds of comments on social media. Some people cheered the demise of horse racing at one more racetrack across the country, saying it was best for the horses. Others lamented the possibility of developers building on the site. Many were incredibly saddened by the impending shutdown, recalling fond days spent at the track in their childhood with family members and friends. After he retired, Bob Barlow's stepfather landed a job as an usher at the trackway because he enjoyed spending time at the track so much. Barlow's stepfather, Tracy Hall, is in a red jacket and pictured with a winning horse after a race. Provided by Bob Barlow Bob Barlow, who now lives in Connecticut, previously lived in East Windsor in Mercer County and would visit the track as a child with his stepfather, who loved watching the horses race and placing bets. Barlow said his stepfather, Tracy Hall, once won $800 from betting on the races in one day. Although Barlow doesn’t remember the horse’s name, he easily recalls the jockey’s name: Wilbur. “My stepfather winds up getting up, standing on top of the chair and screaming, ‘Come on Wilbur, come on Wilbur,’” said Barlow, 72. The horse won, and Hall was elated. “I literally thought he was going to pass out and have a heart attack,” Barlow said, “he was so excited.” When Hall retired from his security guard position at a research facility, he landed an usher job at the track, allowing him to get paid for something he enjoyed, Barlow said. If the track wasn’t busy, he could place his own bets. Occasionally, he would be invited onto the field after the race, when the winning horse — adorned with a bouquet of flowers around its neck — and its owner took photos. He was employee of the month in May 1995, and officials named a race after him, Barlow said. The track’s attendance declined in recent years. Carl Cito celebrated his 11th birthday at Freehold Raceway's restaurant, called the Renaissance Room, with his two grandfathers. Provided by Carl Cito Carl Cito, 26, would regularly visit the track with his two grandfathers — his mother’s father and his father’s father — starting when he was about 4, he said. His father trained and raced horses there, and although Cito still goes to the track now, he notices a difference in attendance. “Before me, it used to be super popular,” he said, referring to the time before he was born. Though he sees some younger people at the track today, it’s mostly an aging crowd. “My friends from the racetrack are mostly older than me,” Cito said. When the closure was announced, Freehold Borough Mayor Kevin Kane blamed track officials for the shutdown. There has been declining interest in standardbred harness racing, despite the raceway’s “long and storied history” in the borough, he said in a statement at the time. Track officials didn’t try to reverse the trends, Kane previously said. Freehold is jointly owned by Penn Entertainment and Greenwood Racing. “Management seemed disinterested in promoting or marketing the venue and failed to capitalize on the advent of sports betting in New Jersey,” Kane previously said. “The facility had become shopworn and dated with little capital improvements to attract new customers,” Kane said. “Attempts to meet with management to discuss promotional opportunities, band nights, car shows and other event-based strategies designed to get new customers into the facility were rebuffed.” In September, Stephen Gallo, the borough’s business administrator, said the horses will be retained by their owners once the track shuts down. The borough, which doesn’t own any of the property involved, plans to authorize a redevelopment study to determine if the area meets the criteria for an “area in need of redevelopment.” That could lead to proposals for a new use for the land. But, the raceway could potentially remain a horse-racing track. The borough has been in communication with state Sen. Vin Gopal, D-Monmouth, who represents the area, and is seeing if anyone is interested in continuing the raceway’s operations, Gallo previously said. “We have received several inquiries from parties interested in racing operations which we are following up on,” he previously said. Freehold Raceway is the nation’s oldest and fastest daytime half-mile harness racing track, according to its website . It first opened in 1853. It features live harness racing for trotters and pacers, and is open seven days and nights a week. It also hosts year-round thoroughbred and harness racing simulcasts from tracks throughout North America. Stacy Fox remembers growing up at Freehold Raceway — both of her parents worked at the track. She was given a mug that's branded with the track's name. Provided by Stacy Fox Fox, who was given a Freehold Raceway-branded mug years ago and has kept the keepsake, said the track is like a “security blanket” to her. Over the years, she spent many weekends and occasional evenings at the track. Its closure is “heartbreaking,” she said. But, “life goes on, the world changes, and things evolve,” Fox said. “And I guess it’s just time for it to close. I guess it’s just not what it once was.” “But, when it was, it was an amazing place,” she added. Stories by Brianna Kudisch Our journalism needs your support. Please subscribe today to NJ.com. Brianna Kudisch may be reached at bkudisch@njadvancemedia.com .Celebrating Half A Century Of Malta-Qatar RelationsGovernor calls Sathya Sai Baba a saint of service

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Nearly half of American teenagers say they are online “constantly” despite of social media and smartphones on their mental health, according to a new report published Thursday by the Pew Research Center. As in past years, YouTube was the single most popular platform teenagers used — 90% said they watched videos on the site, down slightly from 95% in 2022. Nearly three-quarters said they visit YouTube every day. There was a slight downward trend in several popular apps teens used. For instance, 63% of teens said they used TikTok, down from 67% and Snapchat slipped to 55% from 59%. This small decline could be due to pandemic-era restrictions easing up and kids having more time to see friends in person, but it’s . X saw the biggest decline among teenage users. Only 17% of teenagers said they use X, down from 23% in 2022, the year Elon Musk bought the platform. Reddit held steady at 14%. About 6% of teenagers said they use Threads, Meta’s answer to X that launched in 2023. The report comes as countries around the world are grappling with how to handle the effects of social media on young people’s well-being. Australia recently passed a law from social networks, though it’s unclear how it will be able to enforce the age limit — and whether it will come with unintended consequences such as isolating vulnerable kids from their peers. Meta’s messaging service WhatsApp was a rare exception in that it saw the number of teenage users increase, to 23% from 17% in 2022. Pew also asked kids how often they use various online platforms. Small but significant numbers said they are on them “almost constantly.” For YouTube, 15% reported constant use, for TikTok, 16% and for Snapchat, 13%. As in previous surveys, girls were more likely to use TikTok almost constantly while boys gravitated to YouTube. There was no meaningful gender difference in the use of Snapchat, Instagram and Facebook. Roughly a quarter of Black and Hispanic teens said they visit TikTok almost constantly, compared with just 8% of white teenagers. The report was based on a survey of 1,391 U.S. teens ages 13 to 17 conducted from Sept. 18 to Oct. 10, 2024.Kendrick Lamar surprises with new album 'GNX' LOS ANGELES (AP) — Kendrick Lamar gave music listeners an early holiday present with a new album. The Grammy winner released his sixth studio album “GNX” on Friday. The 12-track project is the rapper’s first release since 2022’s “Mr. Morale & The Big Steppers.” Lamar’s new album comes just months after his rap battle with Drake. The rap megastar will headline February's Apple Music Super Bowl Halftime Show in New Orleans. The 37-year-old has experienced massive success since his debut album “good kid, m.A.A.d city” in 2012. Since then, he’s accumulated 17 Grammy wins and became the first non-classical, non-jazz musician to win a Pulitzer Prize. Javascript is required for you to be able to read premium content. Please enable it in your browser settings. Get any of our free email newsletters — news headlines, obituaries, sports, and more.