www 50jili net The National Information Technology Development Agency (NITDA) has indicated that TikTok and X (formerly Twitter) are yet to comply with tax filing requirements in accordance with Nigeria’s regulatory framework. The social media platforms were identified in a report obtained by PRNigeria, titled “Analysis of Compliance with Laws and Misinformation Management by Social Media Platforms in Nigeria.” However, Google, LinkedIn, and Meta have met their tax compliance obligations as outlined in Part III, Sections 3–1, and Part II, Section 10 of the “Code of Practice for Interactive Computer Service Platforms and Internet Intermediaries (CoP for ICSP/II).” “The report underscores the importance of the Code in addressing the dualities of social media as both a tool for progress and a potential source of harm. By enforcing compliance, NITDA seeks to create a transparent and responsible digital ecosystem in Nigeria,” the review reads. ALSO READ: Custodial centres in FCT, Keffi overcrowded — Report The agency urged companies to prioritize compliance, emphasizing that conformity to the Code of Practice is crucial for cultivating trust, ensuring user safety, and preventing the misuse of digital platforms for damaging purposes. The Code, introduced by NITDA in September 2022 in collaboration with the Nigerian Communications Commission (NCC) and the National Broadcasting Commission (NBC), aims to mitigate online harm, promote accountability and create a safer digital environment. Part II, Section 10 of the Code mandates Large Service Platforms (LSPs) to submit annual compliance reports to NITDA to ensure adherence to regulatory standards and foster transparency. It also requires the establishment of physical offices, the appointment of liaison officers for government communication, and the engagement of certified fact-checkers. Already, major LSPs have registered with the Corporate Affairs Commission (CAC). The NITDA report further notes the significant content moderation efforts undertaken by LSPs, including actions on fake accounts and harmful content — child pornography, hate speech, and misinformation. As of 2023, many accounts in Nigeria were closed for breaching the NITDA Code and the community rules of different platforms: 9,610,054 on Google; 691,596 on LinkedIn; 599,776 on TikTok, and 1,198,205 on X. The platforms also deleted millions of posts that violated the provisions of the Code and community guidelines: 59,670,247 posts on Google; 237,837 on LinkedIn; 4,578,858 on TikTok, and 168,500 on X. NIGERIAN TRIBUNECellular traffic congestion in chronic diseases suggests new therapeutic targets November 27, 2024 Whitehead Institute for Biomedical Research Chronic diseases such as diabetes are on the rise and are costly and challenging to treat. Scientists have discovered a common denominator driving these diverse diseases, which may prove to be a promising therapeutic target: proteolethargy, or reduced protein mobility, in the presence of oxidative stress. Facebook Twitter Pinterest LinkedIN Email Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing. Treating chronic disease has proven difficult because there is not one simple cause, like a single gene mutation, that a treatment could target. At least, that's how it has appeared to scientists. However, research from Whitehead Institute Member Richard Young and colleagues, published in the journal Cell on November 27, reveals that many chronic diseases have a common denominator that could be driving their dysfunction: reduced protein mobility. What this means is that around half of all proteins active in cells slow their movement when cells are in a chronic disease state, reducing the proteins' functions. The researchers' findings suggest that protein mobility may be a linchpin for decreased cellular function in chronic disease, making it a promising therapeutic target. In this paper, Young and colleagues in his lab, including postdoc Alessandra Dall'Agnese, graduate students Shannon Moreno and Ming Zheng, and research scientist Tong Ihn Lee, describe their discovery of this common mobility defect, which they call proteolethargy; explain what causes the defect and how it leads to dysfunction in cells; and propose a new therapeutic hypothesis for treating chronic diseases. "I'm excited about what this work could mean for patients," says Dall'Agnese. "My hope is that this will lead to a new class of drugs that restore protein mobility, which could help people with many different diseases that all have this mechanism as a common denominator." "This work was a collaborative, interdisciplinary effort that brought together biologists, physicists, chemists, computer scientists and physician-scientists," Lee says. "Combining that expertise is a strength of the Young lab. Studying the problem from different viewpoints really helped us think about how this mechanism might work and how it could change our understanding of the pathology of chronic disease." Commuter delays cause work stoppages in the cell How do proteins moving more slowly through a cell lead to widespread and significant cellular dysfunction? Dall'Agnese explains that every cell is like a tiny city, with proteins as the workers who keep everything running. Proteins have to commute in dense traffic in the cell, traveling from where they are created to where they work. The faster their commute, the more work they get done. Now, imagine a city that starts experiencing traffic jams along all the roads. Stores don't open on time, groceries are stuck in transit, meetings are postponed. Essentially all operations in the city are slowed. The slow down of operations in cells experiencing reduced protein mobility follows a similar progression. Normally, most proteins zip around the cell bumping into other molecules until they locate the molecule they work with or act on. The slower a protein moves, the fewer other molecules it will reach, and so the less likely it will be able to do its job. Young and colleagues found that such protein slow-downs lead to measurable reductions in the functional output of the proteins. When many proteins fail to get their jobs done in time, cells begin to experience a variety of problems -- as they are known to do in chronic diseases. Discovering the protein mobility problem Young and colleagues first suspected that cells affected in chronic disease might have a protein mobility problem after observing changes in the behavior of the insulin receptor, a signaling protein that reacts to the presence of insulin and causes cells to take in sugar from blood. In people with diabetes, cells become less responsive to insulin -- a state called insulin resistance -- causing too much sugar to remain in the blood. In researchpublished on insulin receptors in Nature Communications in 2022, Young and colleagues reported that insulin receptor mobility might be relevant to diabetes. Knowing that many cellular functions are altered in diabetes, the researchers considered the possibility that altered protein mobility might somehow affect many proteins in cells. To test this hypothesis, they studied proteins involved in a broad range of cellular functions, including MED1, a protein involved in gene expression; HP1α, a protein involved in gene silencing; FIB1, a protein involved in production of ribosomes; and SRSF2, a protein involved in splicing of messenger RNA. They used single-molecule tracking and other methods to measure how each of those proteins moves in healthy cells and in cells in disease states. All but one of the proteins showed reduced mobility (about 20-35%) in the disease cells. "I'm excited that we were able to transfer physics-based insight and methodology, which are commonly used to understand the single-molecule processes like gene transcription in normal cells, to a disease context and show that they can be used to uncover unexpected mechanisms of disease," Zheng says. "This work shows how the random walk of proteins in cells is linked to disease pathology." Moreno concurs: "In school, we're taught to consider changes in protein structure or DNA sequences when looking for causes of disease, but we've demonstrated that those are not the only contributing factors. If you only consider a static picture of a protein or a cell, you miss out on discovering these changes that only appear when molecules are in motion." Can't commute across the cell, I'm all tied up right now Next, the researchers needed to determine what was causing the proteins to slow down. They suspected that the defect had to do with an increase in cells of the level of reactive oxygen species (ROS), molecules that are highly prone to interfering with other molecules and their chemical reactions. Many types of chronic-disease-associated triggers, such as higher sugar or fat levels, certain toxins, and inflammatory signals, lead to an increase in ROS, also known as an increase in oxidative stress. The researchers measured the mobility of the proteins again, in cells that had high levels of ROS and were not otherwise in a disease state, and saw comparable mobility defects, suggesting that oxidative stress was to blame for the protein mobility defect. The final part of the puzzle was why some, but not all, proteins slow down in the presence of ROS. SRSF2 was the only one of the proteins that was unaffected in the experiments, and it had one clear difference from the others: its surface did not contain any cysteines, an amino acid building block of many proteins. Cysteines are especially susceptible to interference from ROS because it will cause them to bond to other cysteines. When this bonding occurs between two protein molecules, it slows them down because the two proteins cannot move through the cell as quickly as either protein alone. About half of the proteins in our cells contain surface cysteines, so this single protein mobility defect can impact many different cellular pathways. This makes sense when one considers the diversity of dysfunctions that appear in cells of people with chronic diseases: dysfunctions in cell signaling, metabolic processes, gene expression and gene silencing, and more. All of these processes rely on the efficient functioning of proteins -- including the diverse proteins studied by the researchers. Young and colleagues performed several experiments to confirm that decreased protein mobility does in fact decrease a protein's function. For example, they found that when an insulin receptor experiences decreased mobility, it acts less efficiently on IRS1, a molecule to which it usually adds a phosphate group. From understanding a mechanism to treating a disease Discovering that decreased protein mobility in the presence of oxidative stress could be driving many of the symptoms of chronic disease provides opportunities to develop therapies to rescue protein mobility. In the course of their experiments, the researchers treated cells with an antioxidant drug -- something that reduces ROS -- called N-acetyl cysteine and saw that this partially restored protein mobility. The researchers are pursuing a variety of follow ups to this work, including the search for drugs that safely and efficiently reduce ROS and restore protein mobility. They developed an assay that can be used to screen drugs to see if they restore protein mobility by comparing each drug's effect on a simple biomarker with surface cysteines to one without. They are also looking into other diseases that may involve protein mobility, and are exploring the role of reduced protein mobility in aging. "The complex biology of chronic diseases has made it challenging to come up with effective therapeutic hypotheses," says Young, who is also a professor of biology at the Massachusetts Institute of Technology. "The discovery that diverse disease-associated stimuli all induce a common feature, proteolethargy, and that this feature could contribute to much of the dysregulation that we see in chronic disease, is something that I hope will be a real game changer for developing drugs that work across the spectrum of chronic diseases." Story Source: Materials provided by Whitehead Institute for Biomedical Research . Original written by Greta Friar. Note: Content may be edited for style and length. Journal Reference : Cite This Page :

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Salesforce Inc earnings missed by $0.03, revenue topped estimatesThe U.S. economy continues to outpace earlier expectations, but rural industries are disproportionately exposed to federal policy and face downside risks in the coming year DENVER, Dec. 12, 2024 (GLOBE NEWSWIRE) -- The U.S. continues to benefit from solid economic growth, low unemployment and moderating inflation. From today's vantage point, the U.S. economy seems likely to continue on that trajectory into 2025. However, the outlook for the rural economy is more volatile and uncertain. Rural industries are disproportionately exposed to federal policy, and the outcome of the 2024 election cycle promises to bring significant changes in the federal government's approach to everything from international trade and immigration to energy exploration and rural economic development. According to a comprehensive year-ahead outlook report from CoBank's Knowledge Exchange , the high level of policy uncertainty facing rural industries adds to their already long list of headwinds and challenges. "The environment we enter in 2025 hasn't fully defined itself yet, but many of the policies proposed by the incoming administration would likely have a negative impact on U.S. agriculture,” said Rob Fox , director of CoBank's Knowledge Exchange. "Open access to export markets and labor availability are critically important for agricultural producers and processors. Depending on how policy plays out, those two areas could be big challenges in 2025 and beyond.” The CoBank 2025 outlook report examines several key factors that will shape agriculture and market sectors that serve rural communities throughout the U.S. U.S. Economy: A New Economic Era Begins Most economists are forecasting 2025 U.S. GDP growth around 2.5%-3.0%, essentially the same as today. However, those forecasts are based on rather mild assumptions on forthcoming policy changes. When taken in isolation, President-elect Trump's proposed policies - tax cuts, decreased labor supply and tariffs on imported goods - are all inflationary. Consequently, longer-term interest rates have already edged higher, and the market has downshifted expectations for further Fed rate cuts in 2025. There is a good chance the proposed tariffs and the crackdown on undocumented immigrants will be more disruptive than markets have priced in, particularly in industries like construction and agriculture. U.S. Government: Trump Administration, Congress Set for Bustling January Start Congress is expected to wrap up the lame duck session of the 118th Congress by Dec. 19, hopefully addressing important pieces of unfinished business. A one-year extension of the 2018 Farm Bill is increasingly likely. President-elect Trump is expected to pursue an ambitious first-100 days of executive orders and other legislative activity that will likely include many of his campaign promises. These may include significant deportation efforts and immigration reform, implementation of tariffs, extending the 2017 tax cuts and providing regulatory relief rolling back the Biden administration's initiatives. The 119th Congress will have a long and challenging to-do list when members return to Washington on Jan. 3. U.S. Agricultural Economy: Trade War Could Send Ag Economy from Bad to Worse The short-lived commodity boom precipitated by global droughts, the war in Ukraine and COVID-19 supply issues is now a distant memory. Row crop prices are down nearly 50% from their 2022 highs. But production costs have remained elevated, and profitability has plunged to decade-plus lows. The silver lining is that dairy and livestock producers are generally profitable due to low feed costs and resilient consumer demand. However, more headwinds may be coming for both the crop and livestock sectors. President-elect Trump rode to victory on two main economic policy proposals: enact significant import tariffs and reduce immigration while deporting undocumented residents. In theory, these policies could achieve some limited objectives, but it is hard to paint them as anything but negative for the U.S. farm economy. Grains, Farm Supply & Biofuels: Policy Uncertainty Weighs on Exports, Biofuels A strengthening U.S. dollar, combined with the potential for trade disputes and record-large South American crops, weigh heavily on the outlook for grain and oilseed prices in 2025. U.S. farmers are widely expected to struggle with further margin compression as weaker commodity prices test farmers' ability to lower production costs. Crop input decisions will be evaluated much more closely with a focus on inputs that provide the greatest return on investment. The bearish outlook for oil prices diminishes the demand picture for ethanol, biodiesel and renewable diesel. Uncertainty over U.S. biofuel policy under the new administration also clouds the demand outlook for biofuels. Animal Protein: Rising Margins Improve Prospects for Growth Falling feed costs and rising producer margins have renewed expansion interest in animal protein segments. However, labor, construction and land costs remain elevated, tempering expectations for any meaningful supply growth in the near term. U.S. beef cow herd expansion is not expected to start until 2026 or 2027. The smaller herd will further support higher feeder and fed cattle prices in the coming year. With consumers now pushing back on beef prices already near historic highs, packer margins will remain under pressure well into 2025. Dairy: Record Investment Will Continue to Grow the Category The U.S. will see an unprecedented $8 billion in new dairy processing investment through 2026. Some of the new plants are poised to come online in 2025, with about half of the investment in the cheese category. The expected surge in cheese and whey output will likely put downward pressure on dairy product prices in the second half of the year. Sourcing additional milk supplies to fill new plant capacity is a looming question. 2023 and 2024 will go down as the first back-to-back years since the late 1960s that U.S. milk production took a downturn. On the flip side, higher component levels in farmgate milk, largely butterfat and protein, have lifted finished product yields. Food & Beverage: Health and Nutrition Take Center Stage The headline news for food, beverage and consumer packaged goods in 2025 is President-elect Trump's nomination of Robert F. Kennedy Jr. to lead the Department of Health and Human Services. Kennedy's purported goals include eliminating ingredients banned in other countries and "getting the chemicals out” of America's food supply. Meanwhile, consumers' renewed focus on their health and the popularity of GLP-1 weight-loss drugs are showing signs of impacting food manufacturers. GLP-1 users purchase around 8% less food compared with average consumers, according to J.P. Morgan research. Food and beverage manufacturers' concerns about volume attrition are likely to continue well into 2025. Power & Energy: What an IRA Rollback Might Look Like President-elect Trump's return to the White House will signal a significant shift in U.S. energy policy. While he has promised to end the Inflation Reduction Act, slowing the clean energy momentum that has accelerated under the IRA may be more difficult than imagined. Popular programs in the IRA have directed significant investments to many rural and economically distressed communities. And more than a dozen House Republicans have voiced concern that repealing the IRA could jeopardize ongoing development in their communities. Clawing back IRA funds that have already been allocated could prove to be very difficult. The more likely scenario is that unallocated IRA funding will be redirected to other priorities. Digital Infrastructure: Rural Connectivity Faces New Challenges Political uncertainty and low participation in the Broadband, Equity, Access and Deployment program raises big questions for bridging the digital divide in the year ahead. The $42.5 billion BEAD program, created by the Infrastructure Investment and Jobs Act, includes an unprecedented level of government support. However, a lack of operator participation could blunt the impact of this well-intended program to bring reliable broadband access to underserved rural areas. Many small operators lack the specialized expertise or financial resources to meet some of the complicated BEAD requirements. Read the full report, The Year Ahead: Forces That Will Shape the U.S. Rural Economy in 2025 . About CoBank CoBank is a cooperative bank serving vital industries across rural America. The bank provides loans, leases, export financing and other financial services to agribusinesses and rural power, water and communications providers in all 50 states. The bank also provides wholesale loans and other financial services to affiliated Farm Credit associations serving more than 77,000 farmers, ranchers and other rural borrowers in 23 states around the country. CoBank is a member of the Farm Credit System, a nationwide network of banks and retail lending associations chartered to support the borrowing needs of U.S. agriculture, rural infrastructure and rural communities. Headquartered outside Denver, Colorado, CoBank serves customers from regional banking centers across the U.S. and also maintains an international representative office in Singapore. CONTACT: Corporate Communications CoBank 800-542-8072 [email protected]

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One day, when actor and comedian Rosie O'Donnell was in her 50s, her body ached and her arms felt sore, but she pushed through the pain, not realizing she was having a massive heart attack. She had surgery to put in a stent that saved her life. Shortly after her 2012 heart attack, O'Donnell shared her experience on her blog. During her 2015 television standup special, she spoke about how the experience changed her life. The segment included a heart attack acronym the comedian coined: HEPPP (hot, exhausted, pain, pale, puke). O'Donnell's candidness about her heart attack helped spread awareness about how it can present differently in women. She's one of countless celebrities over the years who have opened up about their health conditions, including breast cancer, HIV, depression, heart disease and stroke. When celebrities reveal and discuss their health issues, the impact can be far-reaching. It not only helps to educate the public, but it also can reduce stigma and inspire others. "Health disclosures by celebrities do matter, and we know this from decades of research across a lot of different health conditions and public figures," said Dr. Jessica Gall Myrick, a professor of health communication at Pennsylvania State University in University Park. "They absolutely do influence people." Some of the earliest celebrity health disclosures happened in the 1970s and 1980s with U.S. presidents and first ladies. When first lady Betty Ford was diagnosed with breast cancer just weeks after Gerald Ford became president in 1974, she spoke openly about her diagnosis, inviting photographers into the White House and helping make talk of cancer less taboo. In 1987, first lady Nancy Reagan used her breast cancer diagnosis as a chance to advocate for women to get mammograms. Her disclosure came two years after President Ronald Reagan's colon cancer diagnosis, about which the couple was equally as vocal. "Individuals throughout the country have been calling cancer physicians and information services in record numbers," the Los Angeles Times reported after Nancy Reagan's widely publicized surgery. The public showed a similar interest years earlier following Betty Ford's mastectomy. Another major milestone in celebrity health disclosures came in 1991, when 32-year-old NBA superstar Earvin "Magic" Johnson revealed he had tested positive for HIV, the virus that causes AIDS. "Life is going to go on for me, and I'm going to be a happy man," Johnson assured fans during a news conference. He immediately retired, only to return to the Los Angeles Lakers in 1996. His disclosure, along with his work as an advocate for safe sex, helped shatter stigmas around HIV and AIDS. Calls to testing centers increased significantly in the days and weeks after Johnson's announcement. "That celebrity disclosure really helped people see there was a wider susceptibly to HIV," Gall Myrick said. "People were more likely to say, 'I need to think about my own risks.' It was very powerful." When it comes to heart and stroke health, President Dwight Eisenhower helped make heart attacks less frightening and mysterious. During a news conference in 1955, millions of Americans learned from the president's doctors about his heart condition, his treatment, and concrete steps they could take to reduce their own heart attack risk. Other notable figures have shared their health experiences over the years. Soap opera legend Susan Lucci , who was diagnosed with heart disease in 2018, has advocated for women's heart health. Basketball great Kareem Abdul Jabbar talks about his irregular heartbeat, known as atrial fibrillation, and advocates for regular health screenings. Lawyer, author and television personality Star Jones continues to speak about heart disease risk after having lifesaving heart surgery in 2010. Longtime TV and radio personality Dick Clark brought stroke and aphasia into the national spotlight when he returned to hosting "New Year's Rockin' Eve" in Times Square just a year after his 2004 stroke and continued until his death in 2012. And actor and comedian Jamie Foxx recently revealed he had a stroke last year. "Celebrity disclosures represent teachable moments," said Dr. Seth M. Noar, director of the Communicating for Health Impact Lab at the University of North Carolina in Chapel Hill. "Searches for different health conditions often spike in the wake of these types of announcements. They cause people to think about these health issues, learn more about them, and in some cases change their behaviors." Celebrities have also highlighted the importance of CPR and the use of an automated external defibrillator, or AED, to restore a person's heartbeat if they experience cardiac arrest. Interest in CPR and AEDs spiked in 2023 after Buffalo Bills safety Damar Hamlin went into cardiac arrest during an NFL game broadcast on national TV. Views of the American Heart Association's hands-only CPR pages jumped more than 600% in the days following Hamlin's cardiac arrest. Three months later, around 3 million people had watched the AHA's CPR video. Family members of celebrities who have died from a heart issue have also spread awareness. After actor John Ritter died of an undiagnosed aortic dissection in 2003, his wife, actor Amy Yasbeck, started the Ritter Foundation to raise awareness about the condition and help others avoid a misdiagnosis. A literature review published in Systematic Reviews in 2017 found that people are conditioned to react positively to celebrity advice. Research also has found that people often follow advice from celebrities who match how they perceive – or how they want to perceive – themselves. The most effective celebrity disclosures are frequently the ones that tell a compelling story and include clear steps people can take to apply lessons the celebrity learned to their own health situation, Gall Myrick said. "People are more likely to take action when they feel confident and capable." Research has shown that celebrity disclosures often impact calls to hotlines and page views on health-related websites, and they can spark behavioral and even policy changes. Anecdotally, Gall Myrick said, people ask their doctor more questions about health conditions and request medical screenings. Celebrities can have a big impact because people tend to have parasocial relationships with them, Gall Myrick said. These are one-sided relationships in which a person feels an emotional connection with another person, often a celebrity. People may feel as if they know the basketball player they've watched on the court for years, or the Hollywood actor they've followed, she said. They want to comfort them after a health disclosure. Social media has only increased this feeling of familiarity, as celebrities regularly share mundane – but fascinating – details of their daily lives, like what they eat for breakfast, their favorite socks, or the meditation they do before bed. "We spend a lifetime being exposed to celebrities through the media, and over time, you get to know these public figures," Gall Myrick said. "Some feel like friendships." A study published in the journal Science Communication in 2020 compared reactions to actor Tom Hanks, who had COVID-19 early in the pandemic, and an average person with COVID-19. Researchers found that participants identified more with Hanks when it came to estimating their own susceptibility to COVID-19. The participants also felt more emotional about the virus that causes COVID-19 when thinking about it in relation to Hanks versus an average person. When a celebrity reveals a health condition, it's a surprise that may feel personal, especially if they are well-liked and the health issue is dramatic and sudden. "We feel like we know them, and the emotional response is what can then push people out of their routine," Gall Myrick said. Noar said a celebrity health story is often a more interesting and powerful way to learn about a health condition than just the facts, which can feel overwhelming. People are drawn to the slew of media coverage that typically follows a celebrity disclosure, he said. "Some of these high-visibility public figures' stories are now woven into some of these illnesses," Noar said. For example, Angelina Jolie is often linked to the BRCA1 gene mutation after the actor shared she had a preventive double mastectomy because of her elevated breast cancer risk and had her ovaries and fallopian tubes removed because of her increased risk for ovarian cancer. "It's a narrative, a story that humanizes the condition in a way that very informational communication really doesn't," Noar said. "People remember it, and it can potentially be a touch point." After a disclosure, patients may bring up a celebrity's story during a doctor's appointment and connect it to their own care. Today's multiplatform digital culture only amplifies celebrity messages. "You're seeing everyday people react to these events, and that can have a ripple effect too," Gall Myrick said. "We know from research that seeing messages more than once can be impactful. Often it's not just one billboard or one commercial that impacts behavior; it's the drip drip drip over time." Still, there's a cautionary tale to be told around the impact of celebrity health news, especially if the celebrity has died. An unclear cause of death may lead to speculation. Gall Myrick said that guesswork could potentially end up hurting rather than helping if patients were to act on misinformation or a lack of information. "Maybe the death was atypical or it needs more context," she said. "That's where advocacy groups and public health organizations come in. They need to be prepared for announcements or disclosures about celebrity deaths, and to fill in some of those gaps." American Heart Association News covers heart and brain health. Not all views expressed in this story reflect the official position of the American Heart Association. Copyright is owned or held by the American Heart Association, Inc., and all rights are reserved.

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Pembroke Pines, Florida–(Newsfile Corp. – November 27, 2024) – The Closing Signing Service, a leader in providing trusted notary and signing solutions across the U.S., announces a significant milestone of completing over 20,000 successful closings with a growing network of more than 4,000 certified notaries nationwide. This achievement underlines the company’s dedication to streamlining and securing real estate closings for clients coast to coast. Melina Fuenmayor celebrates 20,000 closings with The Closing Signing Service, a leader in real estate transactions. To view an enhanced version of this graphic, please visit: https://images.newsfilecorp.com/files/10926/229024_385a5959c4cf3b38_002full.jpg The Closing Signing Service’s exponential growth reflects its commitment to delivering dependable and efficient signing solutions tailored to the evolving needs of real estate professionals, lenders, and homebuyers. With a stringent notary vetting process and advanced technology integration, the company ensures seamless and secure closings, providing peace of mind to all parties involved. “Reaching this milestone of 20,000 closings is a testament to our team’s hard work and our network of notaries who are committed to excellence in every transaction,” said Melina Fuenmayor, Founder and CEO of The Closing Signing Service. “We are proud to support real estate professionals nationwide and look forward to continuing our journey of growth and innovation in the industry.” Fuenmayor brings extensive experience in business management and a profound understanding of real estate transactions, enabling her to shape a vision that prioritizes both technological innovation and exceptional client service. Her commitment to integrity and operational excellence has guided the company’s expansion, fostering a strong network of skilled notaries and delivering outstanding service in every transaction. The company offers a comprehensive suite of services designed to simplify the signing process for real estate professionals, lenders, and borrowers. From remote online notarization to traditional in-person signings, the company ensures every client’s closing experience is convenient, accurate, and secure. Through advanced technology and a customer-focused approach, The Closing Signing Service provides flexible scheduling, streamlined document management, and real-time status updates, ensuring each transaction is handled smoothly and professionally. The Closing Signing Service operates by connecting clients with certified notaries nationwide who specialize in real estate closings. Once a signing request is made, the company coordinates the details and assigns an experienced notary to the appointment. Each signing is meticulously organized, with secure document handling protocols in place to protect sensitive information. By combining state-of-the-art technology with personalized support, the company offers a seamless process from start to finish, ensuring each client receives the highest level of service and security. With a presence in all 50 states, The Closing Signing Service remains focused on expanding its network, enhancing its digital capabilities, and meeting the increasing demand for reliable, secure signing services. Through its expanding network of experienced notaries, the company continues to simplify the closing process, enabling clients to close deals efficiently and effectively. Melina Fuenmayor, CEO of The Closing Signing Service, setting the standard for nationwide notary excellence. To view an enhanced version of this graphic, please visit: https://images.newsfilecorp.com/files/10926/229024_picture1_550.jpg For more information about The Closing Signing Service and its nationwide network of notaries, visit https://www.theclosingsigningservice.com or connect with them on LinkedIn , Facebook , Instagram , YouTube , and TikTok . About The Closing Signing Service The Closing Signing Service is a nationwide notary agency founded by Melina Fuenmayor, a Venezuelan immigrant and successful entrepreneur. Serving title companies, real estate attorneys, and mortgage professionals, the company provides reliable mobile and remote notary solutions across the U.S., facilitating thousands of real estate closings with excellence and efficiency. To view the source version of this press release, please visit https://www.newsfilecorp.com/release/229024 #distro

MUMBAI: Mumbai owes its megacity status to its port; there’s even a theory that its name draws from ‘Bom Bahia’ or ‘beautiful bay’. And yet, this hallmark in the city’s history has been out of bounds to its people. Security concerns and stringent regulations mean that all but a very few are barred. But the winds of change are blowing at last. From Saturday to Friday, The Heritage Project, in collaboration with the Mumbai Port Trust (MbPT), will take around 1,500 people, in batches, on a tour of the port. Here, visitors will view the vast expanse where ships not only dock but undergo various phases of their lifecycle, getting a glimpse into an institution that has shaped the maritime and trade landscape of the city and the country, at large. The first stop will be the dry docks. “This is where ships are built and repaired. Currently, three ships – a cruise ship and two coast guard ships are under maintenance,” said R D Tripathi, CEO of Mumbai Port Sustainability Foundation (MPSF), the sustainability arm of the MbPT. Smaller ships continue to be built at the Mumbai port, and even some ship-breaking takes place here, although the Alang ship breaking yard in Gujarat is where most ships are dismantled, Tripathi said. Next up are the cruise landing spots, from where many a first-time visitor sets foot in Mumbai. “The terminal for international cruises is near the Green Gate. There is a newer terminal, currently under construction, which will be opened in six months. It will be able to handle 5,000 passengers per ship at a time,” said Tripathi, adding that two floors of this terminal will be open to the public during these tours. But the Mumbai port is all about cargo. According to the MbPT website, 2,014 cargo vessels docked here during FY2023-24. This involved handling a record 67.26 million tonnes of cargo. During this time, only 118 cruise ships docked at the port, 27 of them international and 91 domestic. Critical raw materials needed to build and run the city are offloaded at the Mumbai port. “Liquid bulk, which is petroleum, gasoline and other chemicals, arrive in tankers. They are unloaded and stored at the Jawahar Dweep Oil Terminal and Pir Pau. They are then transported through pipelines to factories and refineries in Mumbai and beyond,” he explained. “Fertilisers and cement are also received. Service offshore vessels are frequent visitors, arriving to stock up on fuel and manpower for offshore drilling vessels.” While the port’s cargo handling is on the rise, a milestone decision was taken in the 1970s, Tripathi says, with an air of mystery. “In its current form, the port has been in development since the 1600s. It was only when the (colonial) British government realised the need for regulation and structure that they notified the MbPT in 1873,” said Tripathi, taking a dive into history. “The 1950s saw the start of containerisation – where goods were not shipped in gunny bags or individually as ‘break bulk’ but in containers. By then, Mumbai had come into its own. So, by the ’70s, the port decided to stop handling containers. It continues to handle other types of cargo.” Tripathi said the decision was meant to prevent the city from being burdened by trucks carrying containers, which would weigh heavily on traffic and the city’s streets. Similarly, to reduce pollution, the MbPT stopped handling coal. The Nava Sheva port, now the Jawaharlal Nehru Port Trust in Navi Mumbai, is the landing spot for most goods. Apart from incoming cargo, Tripathi said the Mumbai port also handles cargo that is exported, in particular, cars, heavy machinery and steel. Those who sign up for the tours will also visit other functional spaces, such as warehouses, godowns, ship berths and watch towers, alongside a war memorial, and a memorial commemorating firefighters who lost their lives in the ship 1944 explosion at the dockyard. The tour ends with a visit to a traditional vessel from the Netherlands currently stationed here, the three-masted clipper, Stad Amsterdam. The tour, however, is all sold out. But, as Tripathi and The Heritage Project say, this is only the first step in a phased opening of a key to Mumbai’s history. More to come!NEW YORK, Dec. 03, 2024 (GLOBE NEWSWIRE) -- Results from the 2024 Travelers Risk Index highlight a concerning increase in distracted driving, with many risky behaviors surpassing pre-pandemic levels. Recently, Jessica Kearney and Ginny Brzezinski from the Travelers Institute, along with Ryan McMahon from Cambridge Mobile Telematics, partnered with D S Simon Media on a nationwide satellite media tour to discuss the dangers of distracted driving, tips to navigate the holidays, and the growing use of telematics to offer solutions. Millions of Americans will be hitting the road this holiday season, and with that comes a rise in distracted driving. While traffic fatalities decreased by 4% last year to 44,450, distracted driving remains a growing issue. According to the 2024 Travelers Risk Index, 78% of consumers believe distracted driving is worse now than a few years ago, with many drivers admitting to risky behaviors: close to 60% are reading texts or emails while driving; 26% are updating or checking social media; and 24% are taking photos or videos. Young drivers, particularly Gen Z, are especially at risk. Compared to overall averages, drivers ages 16-20 engage in some hazardous driving behaviors more frequently, like texting/emailing, scrolling and GPS navigation. Additionally, 41% of parents surveyed said they don’t feel like distracted driving is emphasized enough in drivers ed, so they are taking matters into their own hands. Here are some important tips to help prevent distracted driving: Activate the “Do Not Disturb” feature on your phone to block notifications while driving. Before starting your trip, program your GPS and review the route to avoid distractions while on the road. Consider signing up for a telematics program to promote safe driving habits beyond the holiday season. Finally, don't hesitate to speak up if you see a friend or loved one driving distracted—encourage them to focus on the road. If you're on the phone with someone who's driving, ask them to call you back once they've safely reached their destination. Telematics technology is playing a key role in promoting safer driving by collecting data from connected vehicles, IoT devices, and smartphones. It tracks behaviors such as speeding, hard braking, and distraction, and provides users with feedback to help improve their driving habits. By monitoring performance and encouraging safer choices, telematics helps drivers adopt better habits beyond the holiday season. To learn more about the Travelers Institute, visit travelersinstitute.org . To learn more about Cambridge Mobile Telematics, visit cmt.ai . About Jessica Kearney Jessica Kearney is Vice President for Public Policy at the Travelers Institute, the public policy division of Travelers. In this role, she leads corporate thought leadership initiatives on policy issues of interest to the property casualty insurance sector, as well as the financial services industry more broadly. Her portfolio has included work addressing the economy, cybersecurity, small business advocacy, auto safety, autonomous vehicles and disaster preparedness. She also serves as a member of the company’s Autonomous Vehicles and Electric Vehicles Working Groups. Kearney is co-creator, producer and guest host for the Travelers Institute’s webinar series, which seeks to help business and risk professionals navigate today’s biggest challenges in insurance, business and leadership. She leads operations and initiatives for the Travelers Institute, presents at client and industry conferences, and was named to Insurance Business America’s annual Hot 100 list for 2022. About Ginny Brzezinski Ginny Brzezinski is Assistant Vice President for Public Policy Initiatives at the Travelers Institute, the public policy division of Travelers. In this role, she works on corporate thought leadership initiatives on policy issues of interest to the property casualty insurance sector, as well as the financial services industry more broadly. Brzezinski is a producer for the Travelers Institute’s webinar series, which seeks to help business and risk professionals navigate today’s biggest challenges in insurance, business and leadership. Her portfolio also includes work on the Institute’s podcast and social media. Prior to joining Travelers, Brzezinski worked for more than a decade on Capitol Hill, including as Communications Director for the U.S. Senate Finance Committee, the U.S. Senate Government Affairs Committee and Press Secretary for U.S. Senator Bill Roth. She is the co-author of Comeback Careers, a blueprint for women looking to reinvent, reboot or reimagine careers at 40, 50 and beyond. She holds a Bachelor of Arts degree in Art History from Brown University and completed Masters studies in communications at Boston University. About Ryan McMahon Ryan McMahon is the Senior Vice President of Strategy & Corporate Development at Cambridge Mobile Telematics (CMT), the world’s largest telematics provider. Ryan joined CMT from the insurance industry where he held several leadership roles, introducing new products and insurance services to personal and commercial markets. Ryan is a member of CMT's executive team with responsibilities overseeing corporate development, government, and public affairs. Ryan holds a BA in Psychology from SUNY Potsdam and an MBA from Worcester Polytechnic University. About D S Simon Media: The firm is well known as a leader in the satellite media tour industry and produces tours from its studio and multiple control rooms at its New York headquarters. Clients include top brands in healthcare, technology, travel, financial services, consumer goods, entertainment, retail and non-profits. Established in 1986 the firm has won more than 100 industry awards. About YourUpdateTV: YourUpdateTV is a property of D S Simon Media. The video included and release was part of a media tour that was produced by D S Simon Media on behalf of the Travelers Institute. Dante Muccigrosso Director of Media Integration & Client Reporting E: dantem@dssimon.com C: 973.524.0104 A video accompanying this release is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/96ea9c3b-7434-4a89-83c4-2cdbdf2ccd2b

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Range Cooker Market to Hit $13.96 Billion by 2029, Driven by an 11.6% CAGR from 2022 to 2029Morgan Rogers looked to have given Unai Emery’s side another famous win when he slammed a loose ball home at the death, but referee Jesus Gil Manzano ruled Diego Carlos to have fouled Juve goalkeeper Michele Di Gregorio and the goal was chalked off. It was a disappointment for Villa, who remain unbeaten at home in their debut Champions League campaign and are still in contention to qualify automatically for the last 16. Emiliano Martinez had earlier displayed why he was named the best goalkeeper in the world as his wonder save kept his side level in the second half. The Argentina international paraded his two Yashin Trophies on the pitch before kick-off at Villa Park and then showed why he won back-to-back FIFA awards when he denied Francisco Conceicao. Before Rogers’ moment of drama in the fourth minute of added time, the closest Villa came to scoring was in the first half when Lucas Digne’s free-kick hit the crossbar. But a draw was a fair result which leaves Villa out of the top eight on goal difference and Juventus down in 19th. Before the game Emery called Juventus one of the “best teams in the world, historically and now”, but this was an Italian side down to the bare bones. Only 14 outfield players made the trip from Turin, with striker Dusan Vlahovic among those who stayed behind. The opening 30 minutes were forgettable before the game opened up. Ollie Watkins, still chasing his first Champions League goal, had Villa’s first presentable chance as he lashed an effort straight at Di Gregorio. Matty Cash then had a vicious effort from the resulting corner which was blocked by Federico Gatti and started a counter-attack which ended in Juventus striker Timothy Weah. Villa came closest to breaking the deadlock at the end of the first half when Digne’s 20-yard free-kick clipped the top of the crossbar and went over. Martinez then produced his brilliant save just after the hour. A corner made its way through to the far post where Conceicao was primed to head in at the far post, but Martinez sprawled himself across goal to scoop the ball away. Replays showed most of the ball went over the line, but the Argentinian got there with millimetres to spare. At the other end another fine goal-line block denied John McGinn as Manuel Locatelli got his foot in the way with Di Gregorio beaten. The game looked to be petering out until a last-gasp free-kick saw Rogers slam home, but whistle-happy official Gil Manzano halted the celebrations by ruling the goal out.