CARLSBAD, Calif. , Dec. 12, 2024 /PRNewswire/ -- Ourself, a leader in the next generation of skincare, today announced that clinical data evaluating Ourself's patented delivery technology, Tiered-Release VesiclesTM (TRVs), was published in Dermatologic Surgery , the official journal of the American Society for Dermatologic Surgery. The publication highlights that TRVs have the potential to revolutionize skincare by enabling the delivery of large, bioactive molecules directly into the epidermis and dermis. The Ourself delivery method promises to reshape the way we care for our skin and opens new possibilities for enhancing cosmetic outcomes topically. "Publication of this data reinforces that Ourself is setting a new standard in topical delivery," said Jim Hartman , Ourself's Chief Executive Officer. "We are excited to lead these advancements and look forward to the growth and innovation this breakthrough will inspire for our brand and the industry as a whole." "Tiered-Release Vesicles represent a revolutionary advancement in dermal delivery technology, addressing a stagnation in the industry that has persisted for over four decades," said Ashish C. Bhatia , MD, FAAD, author and board-certified dermatologist and Mohs surgeon at Oak Dermatology. For decades, the skin's outermost layer, the stratum corneum, has long been a barrier that limits the effectiveness of skincare products, blocking essential ingredients from reaching deeper layers. Traditional delivery systems like liposomes have failed to penetrate deeply enough to achieve substantial results—TRVs change this paradigm. "It's not just about the ingredients but also how the ingredients get to where they need to go. Ourself is revolutionary and a game changer in our industry because we've had the same delivery systems for 40 years. Now we have something better," said Amy B. Lewis , MD, board-certified dermatologist at Lewis Dermatology and Associates. "The Tiered-Release Vesicle delivery system is a major step forward for skincare. These developments redefine what is now achievable in topical delivery, unlocking limitless potential for the future of skincare," said Amir Moradi , MD, MBA lead author and double board-certified facial plastic and otolaryngology-head and neck surgeon at Moradi MD. ABOUT OURSELF Leveraging decades of biotech and skincare expertise, Ourself developed a new, scientifically advanced delivery technology to broaden the capabilities of cosmetic skincare forever. Utilizing patented Tiered-Release VesiclesTM, Ourself "hero" products ensure deep ingredient delivery, sending larger molecules, powerful peptides and all-in-one formulations directly to the layer of the skin where they're needed most to improve loss of volume, lines & wrinkles, and uneven pigmentation. Ourself developed the first non-injectable Lip Filler clinically proven to restore volume by delivering two sizes of hyaluronic acid into the lips, topically. Ourself is based in Carlsbad, CA. For more information, visit Ourself.com . REFERENCE: Moradi A, et al. In Vivo and Ex Vivo Evaluation of a Novel Method for Topical Delivery of Macromolecules Through the Stratum Corneum for Cosmetic Applications. Dermatol Surg. 2024 View original content to download multimedia: https://www.prnewswire.com/news-releases/clinical-validation-of-ourself-delivery-technology-published-in-dermatologic-surgery--tiered-release-vesicles-poised-to-revolutionize-skincare-302330774.html SOURCE OurselfCBC resurrects plans for live New Year’s Eve broadcast specials337 jili live casino 。

Published 10:38 pm Monday, December 9, 2024 by Amanda Shavers Dear Dave: I have $100,000 in student loan debt. Since the amount is so large, is there a special place in your Baby Steps plan for it? — Jules Dear Jules: I hope you have a nice, large income with which to fight that big pile of student loan debt. I’ve seen even worse situations, though. I’ve talked to people who went $200,000 into debt for a four-year degree in a field where they’ll make $45,000. Yes, that kind of thinking and behavior is out there, and it’s ridiculous. The fact that it’s a large amount of student loan debt doesn’t change anything. Baby Step 2 is where you pay off all debt except for your home. So, don’t let this student loan debt hang around for years and years. You’ve got to get focused and intense about getting control of your money. That means living on a strict, basics-only monthly budget. After that, start throwing every nickel and dime you can scrape together, and save toward paying off those student loans as fast as possible. Email newsletter signup Your income is your largest wealth-building tool, Jules. You can’t save, and plan for the future, when all your money is flying out the door to pay off debt. — Dave Find a Good Money Market Account Dear Dave: My wife and I are completely debt-free, and we’re saving up for our first house. We currently have about $140,000 in savings, and we’d like to buy a home with cash when the time is right. Where should we put our money, so it will work for us while we save more? — Andy Dear Andy: If I were in your shoes, and maybe looking at a window of three or four years, I’d just park the cash in a good money market account. You won’t make a lot off it, but your money will be safe. I mean, all you’re looking for is a smart place to stash it for a little while. When it comes to long-term investing, I’m a big fan of growth stock mutual funds. The problem with that in your situation would be the volatility of the market. By the time you’ve saved up more money, and spent time deciding on a house, the market may be down. You two are in a great place financially right now. With the path you’re on, just imagine how incredible it will be in a few years to have a new home and be debt-free! — Dave Amanda Shavers joined The Cullman Times in 1997 as the paper's first staff photographer. She has been News Editor since 2008. She is also Content Editor for Cullman Magazine (quarterly), Cullman County Graduation magazine, Fall in Love With Cullman magazine, Salute to Industry magazine and the Senior and Retiree Directory magazine. She is also Content Editor for the weekly St. Clair News-Aegis and she assists with the twice-weekly Athens News Courier. (Column) Big mules ain’t all bad (Column) Robert F. Kennedy Jr.: Will he make America healthy again? (Column) Alabama vs. Auburn, a house divided (Column) The Trump TriumphThe Las Vegas Grand Prix was a mixed bag for Red Bull’s Max Verstappen, who finished fifth in Saturday night’s race on the Strip but clinched his fourth straight Formula One championship . The race was also a mixed bag for Las Vegas sportsbooks a year after they set record betting handles, or amount of money wagered, on the inaugural F1 race on the Strip. Station Sports and BetMGM again reported record handles for the F1 race as both sportsbooks shattered last year’s mark. “The handle was phenomenal,” Red Rock Resort sportsbook director Chuck Esposito said. “It was, by far, the largest F1 handle we had this year and easily surpassed the record handle we had last year on it.” BetMGM, which took the largest wager on last year’s race at $200,000 on Verstappen (who won as a -200 favorite), took twice as much money in bets on Saturday’s event. This year’s race was won in dominant fashion by pole winner George Russell of Mercedes, who closed as the +350 third favorite at Caesars Sportsbook. Betting was way down at the Westgate SuperBook, however. It wrote only 35 percent of what it handled last year, according to vice president of risk Ed Salmons. Caesars also saw a drop in the action. The book shattered its record handle on any auto race on the Las Vegas Grand Prix last year, when vice president of trading Craig Mucklow said it took well over $1 million in wagers. Mucklow said Caesars took in three times as much on the event as the Daytona 500, aka the Super Bowl of NASCAR. Verstappen was the odds-on favorite last year, but closed as the +550 fourth choice at Caesars this year before Saturday’s race. He was behind Ferrari’s Carlos Sainz, the +220 favorite, Sainz’s teammate Charles Leclerc, the +275 second choice, and Russell. McLaren’s Lando Norris was the 9-1 fifth favorite, followed by Mercedes’ Lewis Hamilton, a 22-1 long shot who drove from 10th place to second to give his team a sweep of the top two spots. Russell started on the pole and led every lap. “The handle was not on par this year compared to last, primarily due to George Russell’s dominance, which affected in-play wagering on the event,” Mucklow said. “However, we did benefit from the race being more competitive this year compared to last year’s pre-race (odds).” Sainz and Leclerc finished third and fourth, respectively. Station won on the event, while the Westgate was a small loser overall. “Getting Russell to win was a really good outcome for us,” Esposito said. “That was one of the best cases for us. Outside of some long shots, we clearly did not want Leclerc, Verstappen, Hamilton or (Alpine’s Pierre) Gasly.” Esposito said the record handle was fueled by the city hosting the race for the second year in a row. “Any event that’s here always generates a huge handle,” Esposito said. “Vegas is becoming, if it’s not already, the sports capital of the world, and having a huge event like F1 here with all the hype that surrounds it, I think it will get bigger and bigger every year.”

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