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Princess Beatrice is said to have a wonderful relationship with her stepson Christopher 'Wolfie' Woolf. The eight-year-old son of her husband Edoardo Mapelli Mozzi and his ex fiancée, American architect Dara Huang, is mostly kept out of the limelight, but sometimes he makes an appearance on his mum's social media. On Friday, Dara shared an Instagram story giving a rare insight into Wolfie’s school life. The video was captioned "what an 8-year-old keeps in his school desk" and revealed everything inside. Pokemon cards and the comic book Bunny vs Monkey and the League of Doom by Jamie Smart were on show, and he was also holding Maoam sweets, proving they’re - perhaps surprisingly - not strict when it comes to snacking. Wolfie goes to school in the UK, but spent much of the summer in his mother's native United States. Documenting their time together on Instagram, Dara shared photos of Wolfie cuddling up to her in Wisconsin, as well as searching for ice cream, and snacking on tortilla chips. They also spent time together at a waterside home where he could be seen swinging on the lawn, swimming, and on boat rides. Dara and Edoardo welcomed their son in 2016 before calling off their engagement in 2018. Edo went on to marry Princess Beatrice in 2020 and they now co-parent in a situation Dara has described as "easy". Speaking to Harper’s Bazaar , she said: "Wolfie has had two sets of parents trying to help him on both sides, and I just think: 'The more, the merrier'. I feel lucky to have such positive people around him, who really embrace him." Wolfie has since spent lots of time with the royal family, including attending the annual Christmas church service at Sandringham. Opening up about being a stepmum during the lockdown in 2020, Beatrice told HELLO! : "Homeschooling, that was definitely not my forte! Not going to lie. Sadly, I can't blame that on dyslexia. But I've felt very lucky to have had the chance to work with my bonus son over the course of the school closures. It was a huge learning curve for all of us." Beatrice and Eduardo have since welcomed a child of their own, daughter Sienna, and Dara told her Instagram followers that Wolfie loves his little sister. “They are so cute together."

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Georgetown 100, Albany (NY) 68EXT-608 is under clinical development by Extend Biosciences and currently in Phase II for Hypoparathyroidism. According to GlobalData, Phase II drugs for Hypoparathyroidism have a 60% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval. EXT-608 overview EXT-607 is under development for the treatment of hypoparathyroidism. It is administered subcutaneously and acts by targeting parathyroid hormone 1 and 2 receptor. The drug candidate is a long-acting version of PTH (1-34) and is developed using D-VITylation platform technology that improves the pharmacokinetic properties of peptides and proteins by fusing with Vitamin-D. Extend Biosciences overview Extend Biosciences is a clinical stage biotechnology company that focuses on the development of a novel drug delivery platform technology. The company’s pipeline products include EXT608 which treats hypoparathyroidism and EXT418 which targets diabetes-induced peripheral neuropathy and cachexia. Extend Biosciences’ D-VITylation platform technology improves the pharmacokinetic properties of peptide- and protein-based therapeutics. The company partners to assist in the discovery, development and commercialization of superior therapeutic peptides and proteins. Biosciences is headquartered in Newton, Massachusetts, the US. For a complete picture of EXT-608’s drug-specific PTSR and LoA scores, This content was updated on 12 April 2024 From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s .

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